Drug-Drug Interactions: Cortel AZ 40/8 Tablet may have interaction with pain killers (ibuprofen, aspirin), blood thinners (heparin), medicines used to treat heart problems (digoxin), high blood pressure-lowering medicines (lisinopril, enalapril, ramipril), water pills (amiloride, spironolactone), muscle relaxant (tizanidine), and antibiotics (trimethoprim).

Drug-Food Interactions: Cortel AZ 40/8 Tablet may interact with potassium salt substitutes and potassium supplements, resulting in hyperkalaemia (high levels of potassium in the blood). It may cause severe adverse effects such as irregular heartbeat, muscle paralysis and kidney failure.

Drug-Disease Interactions: People with diabetes, cholestasis (liver disease due to the blocked flow of bile), or impaired kidney function should consult a doctor before taking Cortel AZ 40/8 Tablet .