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Mecoprime-G Tablet 10'S

Mecoprime-G Tablet 10'S

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About Mecoprime-G Tablet

Mecoprime-G Tablet belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Mecoprime-G Tablet consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Mecoprime-G Tablet helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Mecoprime-G Tablet may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Mecoprime-G Tablet . If you are a pregnant or breastfeeding mother, please consult your doctor before taking Mecoprime-G Tablet . Mecoprime-G Tablet causes drowsiness and dizziness, so drive only if you are alert. Mecoprime-G Tablet should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Mecoprime-G Tablet as it could lead to increased dizziness and sleepiness. 

Uses of Mecoprime-G Tablet

Treatment of Neuropathic pain and Epilepsy (fits).

Medicinal Benefits

Mecoprime-G Tablet is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

Directions for Use

Take Mecoprime-G Tablet with or without food. Swallow it as a whole with a glass of water; do not chew or break it.


Store in a cool and dry place away from sunlight

Side Effects of Mecoprime-G Tablet

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

Drug Warnings

Inform your doctor before taking Mecoprime-G Tablet if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Mecoprime-G Tablet without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Mecoprime-G Tablet . Consult your doctor immediately if you experience suicidal tendencies. Keep Mecoprime-G Tablet away from direct sunlight. Do not store Mecoprime-G Tablet above 25ºC and keep it away from direct sunlight.

Drug Interactions

Drug-Drug Interaction: Mecoprime-G Tablet may interact with pain killers (hydrocodone, acetaminophen), antidepressants (duloxetine, escitalopram, sertraline), muscle relaxants (cyclobenzaprine), anti-anxiety drugs (alprazolam), fits medicines (pregabalin), antipsychotics (quetiapine), antibiotics (chloramphenicol), and anti-diabetics (metformin).

Drug-Food Interaction: Avoid alcohol consumption while taking Mecoprime-G Tablet as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Mecoprime-G Tablet may interact with disease conditions such as suicidal tendencies, renal dysfunction, and haemodialysis.

Drug-Drug Interactions Checker List


Habit Forming


Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Special Advise

  • Close monitoring for suicidal thoughts/behaviour is required in people using Mecoprime-G Tablet . 

  • Using Mecoprime-G Tablet in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes, and hyperactivity. 

  • Let your doctor and the laboratory staff know if you are using Mecoprime-G Tablet since Gabapentin may interfere with laboratory tests. 

Disease/Condition Glossary

Epilepsy is the central nervous system's disorder in which brain activity becomes abnormal, leading to rapid fits/seizures episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy fits.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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Avoid consumption of alcohol while taking Mecoprime-G Tablet as it may increase dizziness and sleepiness.

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Mecoprime-G Tablet is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Mecoprime-G Tablet .

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Breast Feeding


Gabapentin in Mecoprime-G Tablet is excreted into breast milk. Please consult your doctor before taking Mecoprime-G Tablet if you are breastfeeding.

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Mecoprime-G Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Let your doctor know if you have any history of liver diseases before taking Mecoprime-G Tablet . Dose adjustment may be needed in patients with liver impairment.

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Let your doctor know if you have any history of kidney diseases before taking Mecoprime-G Tablet . Dose adjustment may be needed in patients with kidney impairment.

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Mecoprime-G Tablet is not recommended in children less than three years of age. The doctor will prescribe the dosage of Mecoprime-G Tablet based on the child's age and weight.

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Mecoprime-G Tablet is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Mecoprime-G Tablet works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Mecoprime-G Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Mecoprime-G Tablet should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Mecoprime-G Tablet is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Mecoprime-G Tablet from the stomach. To avoid this, maintain a gap of two hours between Mecoprime-G Tablet and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.


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