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AF-400 Tablet 1's
AF-400 Tablet 1's

AF-400 Tablet is used to treat a broad range of infections caused due to fungi and yeast. It contains Fluconazole, which kills or prevents the growth of fungi or yeast. It may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Health Queries

I have tinea versicolor on the back of my neck and upper back. How can I treat it?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Tinea versicolor is a common fungal infection that can be treated with over-the-counter antifungal creams or shampoos containing clotrimazole, ketoconazole, or selenium sulfide. Keep the affected area clean and dry, and avoid excessive sweating. Consult your doctor if the patches do not improve after a few weeks of treatment.

I have a fungal infection and changes in skin colour in a sensitive area. Can I use Kevon Lotion with AF-400 Tablet?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

You may use Kevon Lotion (Ketoconazole) with AF-400 Tablet (Fluconazole) for a fungal infection, but only under medical supervision. Please consult your doctor first, as using oral and topical antifungals together in a sensitive area requires proper dosing and monitoring for potential side effects.

I have tinea versicolor on the backside of my neck and shoulders. What should I do?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

You may apply an over-the-counter antifungal cream, lotion, or shampoo containing clotrimazole, ketoconazole, or selenium sulphide as directed. Keep the affected area clean and dry, avoid excessive sweating, and wear loose clothing to reduce moisture. If the patches do not improve, spread, or recur frequently, please see a doctor for stronger oral or topical antifungal treatment.

I have a growing black mark on my chest. Can you please advise me on what to do?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

A growing black mark on the chest should be examined promptly by a doctor or dermatologist, as it may indicate a serious skin condition such as melanoma (a type of skin cancer). Please do not attempt to treat it yourself or use over-the-counter creams until it has been properly diagnosed.

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Side effects of AF-400 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.

Drug-Drug Interactions

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FluconazoleAstemizole
Critical
FluconazoleLomitapide
Critical

Drug-Drug Interactions

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FluconazoleAstemizole
Critical
How does the drug interact with AF-400 Tablet:
When Astemizole is taken with AF-400 Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking AF-400 Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with AF-400 Tablet:
When Lomitapide is taken with AF-400 Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking AF-400 Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with AF-400 Tablet:
When Eliglustat and AF-400 Tablet are taken together, AF-400 Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking AF-400 Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with AF-400 Tablet:
Taking AF-400 Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking AF-400 Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleSotalol
Severe
How does the drug interact with AF-400 Tablet:
Co-administration of AF-400 Tablet with Sotalol may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Sotalol and AF-400 Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without talking to a doctor.
FluconazoleSaquinavir
Severe
How does the drug interact with AF-400 Tablet:
Taking AF-400 Tablet with Saquinavir may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, AF-400 Tablet can be taken with Saquinavir if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluconazoleTolazamide
Severe
How does the drug interact with AF-400 Tablet:
When Tolazamide is taken with AF-400 Tablet, may increase the blood levels and effects of Tolazamide.

How to manage the interaction:
Although taking Tolazamide and AF-400 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. It's important to talk to a doctor about any medications you are taking to avoid any potential risks or side effects. Do not discontinue any medications without consulting a doctor.
FluconazoleAmiodarone
Severe
How does the drug interact with AF-400 Tablet:
Co-administration of Amiodarone together with AF-400 Tablet may raise the effects of Amiodarone which increases the risk of an irregular heart rhythm.

How to manage the interaction:
Even though Amiodarone and AF-400 Tablet interact, they can be used if prescribed by a doctor. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
FluconazoleAtorvastatin
Severe
How does the drug interact with AF-400 Tablet:
When Atorvastatin and AF-400 Tablet are taken together, the blood levels of Atorvastatin may be significantly elevated.

How to manage the interaction:
Taking Atorvastatin in conjunction with AF-400 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FluconazoleDolasetron
Severe
How does the drug interact with AF-400 Tablet:
Co-administration of Dolasetron taken with AF-400 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between AF-400 Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms - like an irregular heart rhythm, a heart condition, or prolonged diarrhea - it's best to call a doctor right away. Other symptoms to watch out for include sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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