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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ancolchin Tablet 10's is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death. It works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. This medicine may cause side effects such as diarrhoea, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Side effects of Ancolchin Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ancolchin Tablet:
Coadministration of Ancolchin Tablet with clarithromycin may increase the blood levels of Ancolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Ancolchin Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Ancolchin Tablet:
Coadministration of Ancolchin Tablet with itraconazole may increase the blood levels of Ancolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Ancolchin Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ancolchin Tablet:
Coadministration of Ancolchin Tablet with darunavir may increase the blood levels of Ancolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Ancolchin Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Ancolchin Tablet:
Using Ancolchin Tablet together with ketoconazole may increase the blood levels of Ancolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketoconazole with Ancolchin Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
How does the drug interact with Ancolchin Tablet:
Co-administration of Ancolchin Tablet with ranolazine may increase the blood levels of Ancolchin Tablet, increasing the risk of serious side effects

How to manage the interaction:
Although taking Ancolchin Tablet and Ranolazine together may possibly result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
ColchicineNefazodone
Severe
How does the drug interact with Ancolchin Tablet:
Taking Ancolchin Tablet and Nefazodone together can increase the blood levels and effects of Ancolchin Tablet.

How to manage the interaction:
Taking Ancolchin Tablet with Nefazodone together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, contact your doctor right away: pain in your stomach, feeling sick, diarrhea, fever, muscle pain, feeling tired, numbness. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Ancolchin Tablet:
Coadministration of Ancolchin Tablet with daclatasvir may increase the blood levels of Ancolchin Tablet, increasing the risk of side effects.

How to manage the interaction:
Although taking Ancolchin Tablet and Daclatasvir together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Ancolchin Tablet:
Coadministration of Ancolchin Tablet and Spironolactone increases blood levels of Ancolchin Tablet and its side effects.

How to manage the interaction:
Although taking Ancolchin Tablet and Spironolactone together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
ColchicineAmprenavir
Severe
How does the drug interact with Ancolchin Tablet:
Amprenavir may raise Ancolchin Tablet levels in the blood to unsafe levels, raising the risk of serious side effects.

How to manage the interaction:
Although taking Ancolchin Tablet and Amprenavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include stomach pain, feeling sick, having diarrhoea, fever, muscle pain, feeling weak or tired, and numbness. Do not discontinue any medications without consulting your doctor.
ColchicineVenetoclax
Severe
How does the drug interact with Ancolchin Tablet:
When Ancolchin Tablet is taken with Venetoclax, the amount of Ancolchin Tablet in the blood can go up.

How to manage the interaction:
Co-administration of Ancolchin Tablet with Venetoclax can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience Stomach pain, diarrhea, nausea, and vomiting. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Ancolchin Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Ancolchin Tablet.

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