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Bderlo 150mg Tablet
Bderlo 150mg Tablet is used to treat lung and pancreatic cancer. It contains Erlotinib which works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In some cases, this medicine may cause side effects such as abdominal pain, bone pain, constipation, cough, diarrhoea, fatigue, fever, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Bderlo 150mg Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
ErlotinibRabeprazole
Critical

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
How does the drug interact with Bderlo 150mg Tablet:
Omeprazole can make Bderlo 150mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Omeprazole and Bderlo 150mg Tablet together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ErlotinibRabeprazole
Critical
How does the drug interact with Bderlo 150mg Tablet:
When used in combination with Bderlo 150mg Tablet, Rabeprazole may prevent the absorption of Bderlo 150mg Tablet into the circulation, which might make Bderlo 150mg Tablet less effective in treating cancer.

How to manage the interaction:
Taking Rabeprazole with Bderlo 150mg Tablet is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
ErlotinibLeflunomide
Severe
How does the drug interact with Bderlo 150mg Tablet:
When Bderlo 150mg Tablet is taken with leflunomide, it increases the risk of causing liver problems.

How to manage the interaction:
Although there is a possible interaction between Bderlo 150mg Tablet and Leflunomide, you can take these medicines together if advised by your doctor. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, liver damage, or bleeding, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
ErlotinibPhenytoin
Severe
How does the drug interact with Bderlo 150mg Tablet:
Phenytoin may decrease the blood levels of Bderlo 150mg Tablet, which may make Bderlo 150mg Tablet less effective in treating your condition.

How to manage the interaction:
Although taking Phenytoin and Bderlo 150mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ErlotinibItraconazole
Severe
How does the drug interact with Bderlo 150mg Tablet:
Coadministration of Itraconazole with Bderlo 150mg Tablet can reduce the metabolism and increase the levels of Bderlo 150mg Tablet in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Itraconazole with Bderlo 150mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of persistent diarrhea, nausea, vomiting, loss of appetite, skin rash, shortness of breath, cough, or fever you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
ErlotinibMitotane
Severe
How does the drug interact with Bderlo 150mg Tablet:
When Bderlo 150mg Tablet is taken with mitotane, it reduces the blood levels of Bderlo 150mg Tablet.This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Bderlo 150mg Tablet with Mitotane can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
ErlotinibEnzalutamide
Severe
How does the drug interact with Bderlo 150mg Tablet:
Taking Enzalutamide with Bderlo 150mg Tablet may decrease the blood levels of Bderlo 150mg Tablet, which may make Bderlo 150mg Tablet less effective.

How to manage the interaction:
Although taking Enzalutamide and Bderlo 150mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
ErlotinibRanitidine bismuth citrate
Severe
How does the drug interact with Bderlo 150mg Tablet:
Coadministration of Ranitidine bismuth citrate with Bderlo 150mg Tablet can interfere with the absorption of Bderlo 150mg Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Ranitidine bismuth citrate with Bderlo 150mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. When taken together, your doctor can recommend other options that won't cause any problems. Do not stop using any medications without talking to a doctor.
ErlotinibLansoprazole
Severe
How does the drug interact with Bderlo 150mg Tablet:
The combination of Bderlo 150mg Tablet with lansoprazole is commonly not advised. Bderlo 150mg Tablet may be less effective at treating your cancer as lansoprazole may interfere with Bderlo 150mg Tablet's absorption into the bloodstream.

How to manage the interaction:
Although taking Lansoprazole and Bderlo 150mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ErlotinibMipomersen
Severe
How does the drug interact with Bderlo 150mg Tablet:
Taking Bderlo 150mg Tablet and Mipomersen can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Bderlo 150mg Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ERLOTINIB-150MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ERLOTINIB-150MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can increase the absorption of Bderlo 150mg Tablet which may lead to higher blood levels of Bderlo 150mg Tablet and possibly increased side effects. Avoid or limit the consumption of Grapefruit juice or Grapefruit while taking Bderlo 150mg Tablet as it can lead to increased risk or severity of side effects. However, if you notice any Burning, tingling, numbness or pain in the hands, arms, feet, or legs, cough or hoarseness, or severe diarrhea, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

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