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निर्माता/विपणक :
ड्यूकेयर कॉन्सेप्ट प्राइवेट लिमिटेड
उपभोग प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
को या उसके बाद समाप्त हो जाएगा :
Jan-27
Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Combee-L Tablet:
Coadministration of Acitretin with Combee-L Tablet can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.
How to manage the interaction:
Taking Acitretin with Combee-L Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
Coadministration of Acitretin with Combee-L Tablet can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.
How to manage the interaction:
Taking Acitretin with Combee-L Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use acitretin if you are pregnant. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Combee-L Tablet:
Taking Combee-L Tablet with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.
How to manage the interaction:
Taking Tranexamic acid with Combee-L Tablet may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Combee-L Tablet with Tranexamic acid may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.
How to manage the interaction:
Taking Tranexamic acid with Combee-L Tablet may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LevonorgestrelEtretinate
Critical
How does the drug interact with Combee-L Tablet:
Using etretinate and Combee-L Tablet can cause severe birth defects.
How to manage the interaction:
Taking Etretinate with Combee-L Tablet can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Using etretinate and Combee-L Tablet can cause severe birth defects.
How to manage the interaction:
Taking Etretinate with Combee-L Tablet can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Combee-L Tablet:
Taking Combee-L Tablet with Tranexamic acid may increase the risk of blood clot formation.
How to manage the interaction:
Taking Combee-L Tablet with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Combee-L Tablet with Tranexamic acid may increase the risk of blood clot formation.
How to manage the interaction:
Taking Combee-L Tablet with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combee-L Tablet:
Using Combee-L Tablet with griseofulvin may reduce Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and griseofulvin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not discontinue any medications without consulting a doctor.
Using Combee-L Tablet with griseofulvin may reduce Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and griseofulvin together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Combee-L Tablet:
A combined use of Combee-L Tablet with mycophenolic acid may reduce the blood levels and effects of Combee-L Tablet, which may make it less reliable as a form of birth control, mycophenolic acid may cause pregnancy loss in the first trimester and also birth defects in the unborn child.
How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Combee-L Tablet, but they can be taken together if a doctor has prescribed them. However, if you take hormone replacement (Combee-L Tablet) for menopause, and if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
A combined use of Combee-L Tablet with mycophenolic acid may reduce the blood levels and effects of Combee-L Tablet, which may make it less reliable as a form of birth control, mycophenolic acid may cause pregnancy loss in the first trimester and also birth defects in the unborn child.
How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Combee-L Tablet, but they can be taken together if a doctor has prescribed them. However, if you take hormone replacement (Combee-L Tablet) for menopause, and if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
LevonorgestrelBrigatinib
Severe
How does the drug interact with Combee-L Tablet:
Brigatinib may lower the blood levels and effects of Combee-L Tablet, making it less effective as a type of birth control. It has also been linked to serious birth abnormalities in newborn children.
How to manage the interaction:
Although taking Combee-L Tablet and brigatinib can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy for menopause, you should contact a doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
Brigatinib may lower the blood levels and effects of Combee-L Tablet, making it less effective as a type of birth control. It has also been linked to serious birth abnormalities in newborn children.
How to manage the interaction:
Although taking Combee-L Tablet and brigatinib can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy for menopause, you should contact a doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Combee-L Tablet:
Taking Combee-L Tablet and Bosentan may lower the blood levels and effects of Combee-L Tablet, making it less effective.
How to manage the interaction:
Although taking Combee-L Tablet and bosentan can lead to interaction, it can be taken if prescribed by a doctor. However, if you experience hot flashes, vaginal dryness, or abdominal bleeding, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Taking Combee-L Tablet and Bosentan may lower the blood levels and effects of Combee-L Tablet, making it less effective.
How to manage the interaction:
Although taking Combee-L Tablet and bosentan can lead to interaction, it can be taken if prescribed by a doctor. However, if you experience hot flashes, vaginal dryness, or abdominal bleeding, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Combee-L Tablet:
Taking Combee-L Tablet and Oxcarbazepine may lower Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and oxcarbazepine together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment (Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.
Taking Combee-L Tablet and Oxcarbazepine may lower Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and oxcarbazepine together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment (Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.
LevonorgestrelRifapentine
Severe
How does the drug interact with Combee-L Tablet:
Taking Combee-L Tablet and Rifapentine may lower Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and rifapentine together can result in an interaction, they can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.
Taking Combee-L Tablet and Rifapentine may lower Combee-L Tablet blood levels and effects.
How to manage the interaction:
Although taking Combee-L Tablet and rifapentine together can result in an interaction, they can be taken if a doctor has prescribed it. If you use hormone replacement treatment(Combee-L Tablet) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
ETHINYLOESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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ETHINYLOESTRADIOL-0.03MG+LEVONORGESTREL-0.15MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.
Product Substitutes
शराब
Unsafe
अप्रिय दुष्प्रभावों से बचने के लिए आपको शराब के साथ शराब का सेवन न करने की सलाह दी जाती है।
गर्भावस्था
Unsafe
सावधानी बरतनी चाहिए। हार्मोनल दवाएँ विकासशील बच्चे को प्रभावित कर सकती हैं। यदि आप गर्भवती हैं या गर्भावस्था की योजना बना रही हैं, तो कॉम्बी-एल टैबलेट 21 का उपयोग करने से पहले डॉक्टर से परामर्श करना उचित है।
स्तनपान
Unsafe
कॉम्बी-एल टैबलेट 21 स्तन के दूध में जा सकता है। यह बच्चे को नुकसान पहुंचा सकता है और दूध के उत्पादन को भी प्रभावित कर सकता है। इसलिए, यह स्तनपान कराने वाली माताओं के लिए असुरक्षित है।
ड्राइविंग
Caution
कॉम्बी-एल टैबलेट 21 का वाहन चलाने या मशीनों का उपयोग करने की क्षमता पर कोई या नगण्य प्रभाव नहीं पड़ता है।
जिगर
Caution
कॉम्बी-एल टैबलेट 21 को सावधानी से लिया जाना चाहिए, खासकर अगर आपको लिवर की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जा सकता है। अगर आपको लिवर की गंभीर बीमारी है तो कॉम्बी-एल टैबलेट 21 लेने से बचें।
किडनी
Caution
कॉम्बी-एल टैबलेट 21 को सावधानी से लिया जाना चाहिए, खासकर अगर आपको किडनी की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जा सकता है। कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
Unsafe
कॉम्बी-एल टैबलेट 21 बच्चों के लिए अनुशंसित नहीं है। कॉम्बी-एल टैबलेट 21 की सुरक्षा और प्रभावकारिता प्रजनन आयु की महिलाओं में स्थापित है। हालाँकि, 16 वर्ष से कम आयु की महिलाओं पर पर्याप्त अध्ययन नहीं किए गए हैं। इसलिए, कॉम्बी-एल टैबलेट 21 को केवल तभी लें जब डॉक्टर द्वारा निर्धारित किया गया हो।
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