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Cort-S Injection is used to treat allergic and inflammatory conditions. It is also used as a replacement therapy for the natural steroid hormone cortisol. It helps reduce inflammation and stabilise the immune response.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking any of these medicines, as there may be an interaction.

  • Abortion pill (Mifepristone)
    Potential effect: May reduce the effectiveness of Cort-S Injection.
  • Anti-epilepsy medicines (carbamazepine, phenytoin)
    Potential effect: May reduce the effectiveness of Cort-S Injection.
  • Pain killers (Ibuprofen, diclofenac)
    Potential effect: May increase the risk of ulcers and gastric irritation.
  • Water pills (Furosemide)
    Potential effect: May increase the risk of hypokalemia (low potassium levels)
  • Blood thinners (warfarin)
    Potential effect: May reduce the effectiveness of warfarin.

Drug-Food Interactions: Cort-S Injection may interact with St. John's wort (an antidepressant herbal supplement).

Drug-Disease Interaction: Inform your doctor if you have a history of the following conditions before taking Cort-S Injection, as it may worsen your condition or cause complications.

  • Severe depression or bipolar disorder
  • Tuberculosis (TB)
  • Glaucoma (increased pressure in the eye)
  • Recent history of a heart attack
  • High blood pressure
  • Diabetes
  • Thyroid problems
  • Stomach ulcers
  • Liver, kidney or heart problems
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Cort-S Injection:
Taking Iopamidol and Cort-S Injection together can increase the risk of seizures, meningitis, and inflammation of the spinal membranes.

How to manage the interaction:
Taking Cort-S Injection with Iopamidol is not recommended, please consult your doctor before taking it. If you experience any symptoms , consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cort-S Injection:
Combining Mifepristone and Cort-S Injection can reduce the effects of Cort-S Injection.

How to manage the interaction:
Taking Cort-S Injection with Mifepristone is not recommended, consult a doctor before taking it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Cort-S Injection:
Taking Enoxacin and Cort-S Injection together can cause tendinitis and tendon rupture.

How to manage the interaction:
Co-administration of enoxacin and Cort-S Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cort-S Injection:
Bupropion is capable of causing seizures (fits), and combining it with Cort-S Injection, may enhance the risk.

How to manage the interaction:
Co-administration of bupropion along with Cort-S Injection can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery, until you have a better understanding of how the medications impact you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cort-S Injection:
Coadministration of Gatifloxacin and Cort-S Injection can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Gatifloxacin and Cort-S Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cort-S Injection:
Co-administration of Cort-S Injection and Ofloxacin can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Although taking Cort-S Injection and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
HydrocortisoneRotavirus vaccine
Severe
How does the drug interact with Cort-S Injection:
The combined use of Rotavirus vaccine and Cort-S Injection can cause a risk of infection.

How to manage the interaction:
Co-administration of Rotavirus vaccine and Cort-S Injection can lead to an interaction, Before receiving the vaccine, you should let your doctor know if you are now receiving or have recently received Cort-S Injection. Your doctor may decide to postpone vaccination in some cases so that your body has time to recover from the side effects of Cort-S Injection therapy. On the other hand, if you recently had the Rotavirus vaccine, your doctor might decide to put off starting your Cort-S Injection therapy for a few weeks.
How does the drug interact with Cort-S Injection:
Co-administration of Adalimumab and Cort-S Injection together can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of adalimumab and Cort-S Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneLomefloxacin
Severe
How does the drug interact with Cort-S Injection:
Taking Lomefloxacin and Cort-S Injection together can cause tendinitis and tendon rupture.

How to manage the interaction:
Co-administration of lomefloxacin and Cort-S Injection can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cort-S Injection:
The use of Etanercept and Cort-S Injection can increase the risk of infections.

How to manage the interaction:
Co-administration of etanercept and Cort-S Injection can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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