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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ddr-D 60/30 Cap is used to treat gastroesophageal reflux disease (GERD) and relieve heartburn. It contains Dexlansoprazole and Domperidone. It works by inhibiting the action of proton pumps, which produce stomach acid. As a result, it reduces the amount of acid the stomach produces while preventing excess acid from flowing back into the food pipe. It also inhibits dopamine receptors in the upper digestive tract. As a result, food moves more quickly through the stomach and into the intestine.

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Drug-Drug Interactions

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DexlansoprazoleGefitinib
Severe
DexlansoprazoleNelfinavir
Severe

Drug-Drug Interactions

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DexlansoprazoleGefitinib
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness.

How to manage the interaction:
Although there is a possible interaction, DDR-D 60 mg/30 mg Capsule can be taken with gefitinib if advised by a doctor. Do not stop using any medications without talking to a doctor.
DexlansoprazoleNelfinavir
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule may decrease the absorption and blood levels of Nelfinavir making it less effective.

How to manage the interaction:
Taking DDR-D 60 mg/30 mg Capsule with Nelfinavir can possibly lead to an interaction. Consult a doctor if you have any concerns, he/she may prescribe alternatives that do not interact. Do not discontinue the medication without consulting a doctor.
DexlansoprazolePazopanib
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule may interfere with the absorption of Pazopanib and reduce its effectiveness.

How to manage the interaction:
Although there is a possible interaction, DDR-D 60 mg/30 mg Capsule can be taken with Pazopanib if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
DexlansoprazoleTacrolimus
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Taking tacrolimus with DDR-D 60 mg/30 mg Capsule may significantly increase the blood levels of tacrolimus which may lead to infections, high sugars, kidney problems, high blood pressure, heart problems, low magnesium levels and hyperkalemia(high potassium levels in the blood),

How to manage the interaction:
Although there is a possible interaction, DDR-D 60 mg/30 mg Capsule can be taken with tacrolimus if prescribed by the doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations, muscle spasm, shaking, and seizures(fits). Do not stop using any medications without consulting a doctor.
DexlansoprazoleErlotinib
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule with Erlotinib may interfere with the absorption of erlotinib making it less effective.

How to manage the interaction:
Taking DDR-D 60 mg/30 mg Capsule with Erlotinib can possibly lead to an interaction. Consult a doctor if you have any concerns, he/she may prescribe alternatives that do not interact. Do not discontinue the medication without consulting a doctor.
DexlansoprazoleDasatinib
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule decreases blood levels of Dasatinib.

How to manage the interaction:
Taking DDR-D 60 mg/30 mg Capsule with Dasatinib can lead to an interaction. Consult a doctor if you experience any unusual symptoms. Do not discontinue the medication without consulting a doctor.
DexlansoprazoleAtazanavir
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule may decrease the absorption and blood levels of Atazanavir, making it less effective.

How to manage the interaction:
Taking DDR-D 60 mg/30 mg Capsule with Atazanavir can possibly lead to an interaction. Consult a prescriber, the doctor may suggest safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with atazanavir. Do not discontinue the medication without consulting a doctor.
DexlansoprazoleMethotrexate
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of Methotrexate with DDR-D 60 mg/30 mg Capsule can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Methotrexate and DDR-D 60 mg/30 mg Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, or body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
DexlansoprazoleAcalabrutinib
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Co-administration of DDR-D 60 mg/30 mg Capsule may interfere with the absorption of Acalabrutinib capsules and reduce its effectiveness.

How to manage the interaction:
Consult your doctor if you are taking DDR-D 60 mg/30 mg Capsule and acalabrutinib. The doctor may prescribe alternatives that do not interact with acalabrutinib or interact to a lesser extent.
DomperidoneToremifene
Severe
How does the drug interact with DDR-D 60 mg/30 mg Capsule:
Coadministration of DDR-D 60 mg/30 mg Capsule with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking DDR-D 60 mg/30 mg Capsule and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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