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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dexford 4mg Tablet is used to treat inflammatory conditions such as allergic disorders and skin conditions. It is also used to treat ulcerative colitis, arthritis, lupus, psoriasis and breathing disorders. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy. It contains Dexamethasone, which works by blocking the release of substances that cause inflammation. Some people may experience side effects like weight gain, indigestion, headache, dizziness, rash, fluid retention (swelling in your hands or ankles), sleep problems, mild mood changes and nausea. Inform the doctor if you have an infection that affects the whole body or if you need to have a vaccination, particularly live virus vaccines.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dexford 4mg Tablet:
When Dexford 4mg Tablet is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Dexford 4mg Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexford 4mg Tablet:
Co-administration of Desmopressin with Dexford 4mg Tablet may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Dexford 4mg Tablet and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexford 4mg Tablet:
When Regorafenib is taken with Dexford 4mg Tablet, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Dexford 4mg Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Dexford 4mg Tablet:
When Rilpivirine is taken with Dexford 4mg Tablet, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Dexford 4mg Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dexford 4mg Tablet:
Taking Dexford 4mg Tablet with Thalidomide may increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction, Dexford 4mg Tablet can be taken with Thalidomide if prescribed by the doctor. Consult the doctor immediately if you experience signs and symptoms of blood clots such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness, or swelling in an arm or leg. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexford 4mg Tablet:
Taking Dexford 4mg Tablet with Bosutinib can decrease the blood levels of Bosutinib, reducing its effectiveness in treating your condition.

How to manage the interaction:
Although there is an interaction between Bosutinib and Dexford 4mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexford 4mg Tablet:
Taking fentanyl with Dexford 4mg Tablet may reduce the blood levels of fentanyl, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although there is an interaction between diphenhydramine and ketamine, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience watery eyes, excessive sweating, body aches, abdominal cramping, vomiting, diarrhea. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Dexford 4mg Tablet:
Taking Ciprofloxacin with Dexford 4mg Tablet may cause tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction between Dexford 4mg Tablet and Ciprofloxacin, but can be taken together if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexford 4mg Tablet:
Co-administration of Dexford 4mg Tablet with Baricitinib can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Dexford 4mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, severe abdominal pain, nausea, or vomiting, consult a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dexford 4mg Tablet:
Taking Dexford 4mg Tablet with Deflazacort may significantly reduce the blood levels of deflazacort, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dexford 4mg Tablet and Deflazacort together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-4MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Dexford 4mg Tablet with Caffeine may increase the side effects of Dexford 4mg Tablet. Avoid consuming caffeine while taking Dexford 4mg Tablet.

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