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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Edicord 40 mg Injection is used to treat symptoms associated with allergic reactions or inflammatory conditions. This medicine contains methylprednisolone, a corticosteroid that works by inhibiting the production of certain chemical messengers that cause inflammation. Thus, helps reduce swelling, redness, and itching. Let your doctor informed about your complete medical and medication history.
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Drug-Drug Interactions

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MethylprednisoloneMifepristone
Critical
MethylprednisoloneVigabatrin
Critical

Drug-Drug Interactions

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MethylprednisoloneMifepristone
Critical
How does the drug interact with Edicord 40 mg Injection:
When Edicord 40 mg Injection is taken with Mifepristone, it may decrease the levels of Edicord 40 mg Injection, which may be less effective in treating your condition.

How to manage the interaction:
Taking Edicord 40 mg Injection with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneVigabatrin
Critical
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Edicord 40 mg Injection and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Edicord 40 mg Injection with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneIohexol
Critical
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Edicord 40 mg Injection with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneBempedoic acid
Severe
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Bempedoic acid with Edicord 40 mg Injection can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Edicord 40 mg Injection if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneDesmopressin
Severe
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Desmopressin with Edicord 40 mg Injection together may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Desmopressin and Edicord 40 mg Injection can cause an interaction, but it can be taken if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood), Contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneCiprofloxacin
Severe
How does the drug interact with Edicord 40 mg Injection:
Coadministration of ciprofloxacin with Edicord 40 mg Injection can increase the risk of tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction, Edicord 40 mg Injection can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience any symptoms such as pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneOfloxacin
Severe
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Edicord 40 mg Injection and Ofloxacin can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Although taking Edicord 40 mg Injection and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneClarithromycin
Severe
How does the drug interact with Edicord 40 mg Injection:
Taking Clarithromycin with Edicord 40 mg Injection together may significantly increase the blood levels of Edicord 40 mg Injection.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Edicord 40 mg Injection if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneGatifloxacin
Severe
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Edicord 40 mg Injection and Gatifloxacin together can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Edicord 40 mg Injection and Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneCeritinib
Severe
How does the drug interact with Edicord 40 mg Injection:
Taking Edicord 40 mg Injection with ceritinib may significantly increase the blood levels of Edicord 40 mg Injection.

How to manage the interaction:
Although taking Edicord 40 mg Injection and ceritinib together can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience swelling, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Edicord 40 mg Injection with Grapefruit may increase the blood level of Edicord 40 mg Injection. Avoid consuming Grapefruit and Grapefruit juice while taking Edicord 40 mg Injection.

Edicord 40 mg Injection Substitute

Substitutes safety advice
  • Depopred 40 Injection 2 ml

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    39.85per tablet
  • Predvia Injection 2 ml

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    45.90per tablet
  • Mepresso-D 40 mg Injection 2 ml

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    29.70per tablet
  • Neo-Drol 40 mg Injection 1's

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    45.90per tablet
  • Bernisal 40 mg Injection 1's

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    51.00per tablet

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