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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Edicord 40 mg Injection is used to treat symptoms associated with allergic reactions or inflammatory conditions. This medicine contains methylprednisolone, a corticosteroid that works by inhibiting the production of certain chemical messengers that cause inflammation. Thus, helps reduce swelling, redness, and itching. Let your doctor informed about your complete medical and medication history.
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Edicord 40 mg Injection:
Co-administration of Edicord 40 mg Injection and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Edicord 40 mg Injection with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
When Edicord 40 mg Injection is taken with Mifepristone, it may decrease the levels of Edicord 40 mg Injection, which may be less effective in treating your condition.

How to manage the interaction:
Taking Edicord 40 mg Injection with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Edicord 40 mg Injection with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Norfloxacin with Edicord 40 mg Injection can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Norfloxacin with Edicord 40 mg Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
The use of Etanercept with Edicord 40 mg Injection can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Edicord 40 mg Injection, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Taking Clarithromycin with Edicord 40 mg Injection together may significantly increase the blood levels of Edicord 40 mg Injection.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Edicord 40 mg Injection if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Edicord 40 mg Injection:
Taking Thalidomide together with Edicord 40 mg Injection may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Edicord 40 mg Injection together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Using adalimumab together with Edicord 40 mg Injection may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Edicord 40 mg Injection and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Edicord 40 mg Injection:
Using baricitinib together with Edicord 40 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Edicord 40 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, severe abdominal pain, nausea, or vomiting, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Edicord 40 mg Injection:
Using cladribine together with Edicord 40 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Taking Cladribine with Edicord 40 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Edicord 40 mg Injection with Grapefruit may increase the blood level of Edicord 40 mg Injection. Avoid consuming Grapefruit and Grapefruit juice while taking Edicord 40 mg Injection.

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