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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Edicord 40 mg Injection is used to treat symptoms associated with allergic reactions or inflammatory conditions. This medicine contains methylprednisolone, a corticosteroid that works by inhibiting the production of certain chemical messengers that cause inflammation. Thus, helps reduce swelling, redness, and itching. Let your doctor informed about your complete medical and medication history.
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Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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How does the drug interact with Edicord 40 mg Injection:
When Edicord 40 mg Injection is taken with Mifepristone, it may decrease the levels of Edicord 40 mg Injection, which may be less effective in treating your condition.

How to manage the interaction:
Taking Edicord 40 mg Injection with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Edicord 40 mg Injection with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Edicord 40 mg Injection and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Edicord 40 mg Injection with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Using adalimumab together with Edicord 40 mg Injection may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Edicord 40 mg Injection and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Norfloxacin with Edicord 40 mg Injection can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Norfloxacin with Edicord 40 mg Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneCertolizumab
Severe
How does the drug interact with Edicord 40 mg Injection:
Using Edicord 40 mg Injection together with certolizumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Edicord 40 mg Injection and Certolizumab together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: a bad infection, sepsis, problems, fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, losing weight, or pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Levofloxacin with Edicord 40 mg Injection may increase the risk of tendinitis(inflammation of the thick fibrous cords that attach muscle to bone).

How to manage the interaction:
Concomitant administration of levofloxacin with Edicord 40 mg Injection can result in an interaction, it can be taken if a doctor has advised it. If you experience pain, swelling, or inflammation in a tendon location such as the back of the ankle, shoulder, biceps, hand, or thumb, call a doctor immediately. You should also refrain from exercising or using the afflicted region until a doctor gives you further instructions. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
The use of Etanercept with Edicord 40 mg Injection can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Edicord 40 mg Injection, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Coadministration of posaconazole with Edicord 40 mg Injection may significantly increase the blood levels of Edicord 40 mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Edicord 40 mg Injection, it can be taken if a doctor has advised it. However, if you experience swelling, weight gain, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Edicord 40 mg Injection:
Co-administration of Ketoconazole and Edicord 40 mg Injection the levels of Edicord 40 mg Injection in the blood may be greatly increased.

How to manage the interaction:
Although taking Ketoconazole and Edicord 40 mg Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the symptoms such as swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts(blurred vision), irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, decreased ability to fight infections, or a severe asthma attack, consult a doctor. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLPREDNISOLONE-40MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Edicord 40 mg Injection with Grapefruit may increase the blood level of Edicord 40 mg Injection. Avoid consuming Grapefruit and Grapefruit juice while taking Edicord 40 mg Injection.

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