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Firam-500 Tablet is used to treat alcohol dependence or chronic alcoholism. It contains Disulfiram, which works by blocking an enzyme that breaks down alcohol in our body. This results in a higher level of acetaldehyde in the blood, causing discomfort and physical reactions. It can help alcohol-addicted people who have decided to quit alcohol drinking by deterring them from drinking again. So, it acts as a supportive agent in the treatment of alcoholism. It may cause common side effects such as drowsiness, tiredness, headache, acne, flushing (warmth, redness, or tingly feeling), sweating, increased thirst, swelling, rapid weight gain, nausea, severe vomiting, neck pain, throbbing headache, blurred vision, fast or pounding heartbeats or fluttering in your chest, confusion, weakness, spinning sensation, feeling unsteady, or and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. Do not take this medicine if you have consumed alcohol within the past 12 hours.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Drug-Drug Interactions

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DisulfiramBenznidazole
Critical
DisulfiramParaldehyde
Critical

Drug-Drug Interactions

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DisulfiramBenznidazole
Critical
How does the drug interact with Firam-500 Tablet:
Coadministration of Firam-500 Tablet with Benznidazole can increase the risk of side effects.

How to manage the interaction:
Taking benznidazole and Firam-500 Tablet together is advised as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, weakness, shortness of breath, or palpitations, contact your doctor immediately.
DisulfiramParaldehyde
Critical
How does the drug interact with Firam-500 Tablet:
Coadministration of Paraldehyde and Firam-500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paraldehyde and Firam-500 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience palpitations, difficulty breathing, vomiting, sweating, chest pain, dizziness, or blurred vision contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Firam-500 Tablet:
Coadministration of Firam-500 Tablet with Metronidazole can increase the risk of side effects.

How to manage the interaction:
Taking Metronidazole and Firam-500 Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
DisulfiramAmprenavir
Critical
How does the drug interact with Firam-500 Tablet:
Coadministration of Amprenavir and Firam-500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amprenavir and Firam-500 Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like difficulty breathing, vomiting, sweating, palpitation, or dizziness, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Firam-500 Tablet:
Co-administration of Ritonavir with Firam-500 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Firam-500 Tablet with ritonavir can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor if you experience headaches, difficulty breathing, vomiting, excessive sweating, chest pain, palpitations, dizziness, or blurred vision. Do not stop using any medications without a doctor's advice.
DisulfiramTipranavir
Severe
How does the drug interact with Firam-500 Tablet:
Co-administration of Tipranavir with Firam-500 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Tipranavir with Firam-500 Tablet can lead to an interaction, it can be taken if your doctor advises. However, consult the doctor immediately if you experience any symptoms like palpitations, excessive sweating, chest pain, or ringing of the ears. Do not stop using any medications without a doctor's advice.
How does the drug interact with Firam-500 Tablet:
Coadministration of Firam-500 Tablet and Leflunomide can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Firam-500 Tablet and Leflunomide, but it can be taken if prescribed by a doctor. If you have any of these symptoms fever, vomiting, stomach pain, dark urine, or yellowing of skin and eyes, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Firam-500 Tablet:
Co-administration of Firam-500 Tablet and Sertraline can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Firam-500 Tablet with Sertraline can lead to an interaction, it can be taken if advised by your doctor. However, consult the doctor immediately if you experience headache, vomiting, excessive sweating, or thirst. Do not stop using any medications without a doctor's advice.
How does the drug interact with Firam-500 Tablet:
Co-administration of Firam-500 Tablet and Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Firam-500 Tablet and Teriflunomide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience dizziness, fever, joint pain, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DisulfiramLomitapide
Severe
How does the drug interact with Firam-500 Tablet:
Coadministration of Firam-500 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Firam-500 Tablet and Lomitapide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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