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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Gcdex 4 mg Tablet 10's is used to treat inflammatory conditions such as allergic disorders and skin conditions. It is also used to treat ulcerative colitis, arthritis, lupus, psoriasis and breathing disorders. Furthermore, it is approved for the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with a body weight of at least 40 kg) who require supplemental oxygen therapy. It contains Dexamethasone, which works by blocking the release of substances that cause inflammation. Some people may experience side effects like weight gain, indigestion, headache, dizziness, rash, fluid retention (swelling in your hands or ankles), sleep problems, mild mood changes and nausea. Inform the doctor if you have an infection that affects the whole body or if you need to have a vaccination, particularly live virus vaccines.

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Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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How does the drug interact with Gcdex 4mg Tab:
When Regorafenib is taken with Gcdex 4mg Tab, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Gcdex 4mg Tab can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Gcdex 4mg Tab:
When Rilpivirine is taken with Gcdex 4mg Tab, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Gcdex 4mg Tab can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcdex 4mg Tab:
Co-administration of Desmopressin with Gcdex 4mg Tab may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Gcdex 4mg Tab and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcdex 4mg Tab:
When Gcdex 4mg Tab is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Gcdex 4mg Tab can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gcdex 4mg Tab:
Taking lemborexant with Gcdex 4mg Tab may reduce the blood levels of lemborexant, which may make the medication less effective in treating your condition.

How to manage the interaction:
Taking Lemborexant with Gcdex 4mg Tab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Gcdex 4mg Tab:
Taking Gcdex 4mg Tab with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Gcdex 4mg Tab can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gcdex 4mg Tab:
Taking Gcdex 4mg Tab and Tolvaptan together may possibly reduce the effects of Tolvaptan.

How to manage the interaction:
Although taking Gcdex 4mg Tab and tolvaptan together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue the medication without consulting a doctor.
DexamethasoneVoclosporin
Severe
How does the drug interact with Gcdex 4mg Tab:
When Gcdex 4mg Tab is taken with Voclosporin, may reduce the blood levels of Voclosporin.

How to manage the interaction:
Co-administration of Gcdex 4mg Tab with Voclosporin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having symptoms, let your doctor know right away. They can recommend other options that won't cause any problems. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Gcdex 4mg Tab:
Gcdex 4mg Tab and Ofloxacin co-administration can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Taking Ofloxacin with Gcdex 4mg Tab together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gcdex 4mg Tab:
Taking Ciprofloxacin with Gcdex 4mg Tab may cause tendinitis(a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture(an injury that is usually painful and likely to affect your ability to walk).

How to manage the interaction:
Although there is an interaction between Gcdex 4mg Tab and Ciprofloxacin, but can be taken together if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DEXAMETHASONE-4MgCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEXAMETHASONE-4MgCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Gcdex 4mg Tab with Caffeine may increase the side effects of Gcdex 4mg Tab. Avoid consuming caffeine while taking Gcdex 4mg Tab.

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