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Gentakem-D Eye/Ear Drops is used to treat eye and ear bacterial infections. It contains Dexamethasone and Gentamicin. Dexamethasone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen, and itchy. Gentamicin is an aminoglycoside antibiotic that prevents the synthesis of essential proteins bacteria require to carry out vital functions.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Gentakem-D Eye/Ear Drops 10 ml
  • Take healthy and balanced diet.
  • Exercise regularly and maintain the healthy lifestyle.
  • Reduce the intake of caffeine.
  • Use a pillow and elevate your head while sleeping.
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
When Regorafenib is taken with Gentakem-D Eye/Ear Drops 10 ml, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Gentakem-D Eye/Ear Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Co-administration of Desmopressin with Gentakem-D Eye/Ear Drops 10 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Gentakem-D Eye/Ear Drops 10 ml and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
When Gentakem-D Eye/Ear Drops 10 ml is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Gentakem-D Eye/Ear Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRilpivirine
Critical
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
When Rilpivirine is taken with Gentakem-D Eye/Ear Drops 10 ml, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Gentakem-D Eye/Ear Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
GentamicinBacitracin
Severe
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Taking Gentakem-D Eye/Ear Drops 10 ml with bacitracin may increase the risk of serious side effects such as respiratory depression, kidney problems, and hearing loss.

How to manage the interaction:
Although there is a possible interaction, Gentakem-D Eye/Ear Drops 10 ml can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, (or) signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Co-administration of Tenofovir alafenamide may cause kidney problems and combining it Gentakem-D Eye/Ear Drops 10 ml may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Gentakem-D Eye/Ear Drops 10 ml can be taken with tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
GentamicinIopamidol
Severe
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Co-administration of Iopamidol with Gentakem-D Eye/Ear Drops 10 ml may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Gentakem-D Eye/Ear Drops 10 ml with Iopamidol can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let your doctor know right away. These changes could be a sign of problems with your kidneys, diabetes, or other health issues. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without a doctor's advice.
GentamicinMivacurium chloride
Severe
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Co-administration of Mivacurium with Gentakem-D Eye/Ear Drops 10 ml can make it more effective as a therapy.

How to manage the interaction:
Taking Gentakem-D Eye/Ear Drops 10 ml with Mivacurium chloride together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Co-administration of of clindamycin with Gentakem-D Eye/Ear Drops 10 ml may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, clindamycin can be taken with Gentakem-D Eye/Ear Drops 10 ml if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
How does the drug interact with Gentakem-D Eye/Ear Drops 10 ml:
Coadministration of Sirolimus with Gentakem-D Eye/Ear Drops 10 ml may increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction, Gentakem-D Eye/Ear Drops 10 ml can be taken with sirolimus if prescribed by the doctor. Consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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