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Hansepran 100 Capsule 10's
Hansepran 100 Capsule 10's
Hansepran 100 Capsule 10's
Hansepran 100 Capsule is used to treat leprosy (infectious disease-causing skin lesions and nerve damage). It contains Clofazimine, which works by inhibiting the growth of disease-causing organisms (Mycobacterium leprae) in the body. In some cases, this medicine may cause side effects such as stomach and epigastric pain, diarrhoea, nausea, and vomiting.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Health Queries

If I develop a leprosy reaction again, what treatment should I take?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

If you have another leprosy reaction, your doctor may treat it with anti-inflammatory medicines such as corticosteroids. In some cases, immunomodulatory drugs may be used to control the immune reaction, depending on the severity. It is important to seek medical care promptly and continue your regular leprosy treatment as advised by your doctor. Do not try to treat it on your own, as improper treatment may lead to permanent nerve damage and disability.

I have had continuous leprosy reactions with nodules for the past month. Please suggest an appropriate tablet to manage this, as well as the high fever, which is unbearable.

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Continuous leprosy reactions with nodules and high fever usually indicate a severe leprosy reaction. Medicines such as prednisolone (a steroid) or clofazimine (an anti-leprosy agent) may be prescribed to prevent permanent nerve damage, but must be closely supervised by a doctor. Please visit a hospital or your treating doctor immediately to prevent complications and treat the fever safely.

Are there any side effects from the MDT treatment I took for leprosy for two years?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Yes, MDT treatment for leprosy may cause side effects such as skin rashes, nausea, diarrhoea, stomach upset, fatigue, skin discolouration, reddish urine, and flu-like symptoms. Most side effects are mild and resolve on their own, but inform your doctor if you notice persistent or severe symptoms.

As a leprosy patient on medication for over three years, should I continue or stop my treatment?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Do not stop your leprosy treatment on your own. The duration of treatment depends on the type of leprosy and your clinical response, so please consult your doctor to confirm whether treatment can be safely stopped or needs to be continued.

What cream treatment is recommended for the white spots caused by leprosy, and what precautions should I take for this disease?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

There is no specific cream that can cure leprosy. The primary treatment is multidrug therapy (MDT) prescribed by your doctor, which may include dapsone, rifampicin, and clofazimine. Mild moisturisers or sunscreen can protect the skin and prevent dryness or sun damage. Precautions include avoiding skin injuries or burns, maintaining good hygiene, taking all medicines exactly as prescribed, attending regular follow-ups to monitor skin and nerve health, and informing close contacts if needed for early detection.

Have a query?

Side effects of Hansepran 100 Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid triggering foods like spicy and fatty foods.
  • Eat smaller meals and digestible foods.
  • Regular exercise can improve gastrointestinal health.
  • Avoid sleeping immediately after eating as it can worsen digestion and lead to discomfort.
  • Drink plenty of water to stay hydrated.
  • Manage stress through relaxation techniques.

Drug-Drug Interactions

verifiedApollotooltip
ClofazimineZiprasidone
Critical
ClofazimineMesoridazine
Critical

Drug-Drug Interactions

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ClofazimineZiprasidone
Critical
How does the drug interact with Hansepran 100 Capsule:
Taking Hansepran 100 Capsule with Ziprasidone can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Ziprasidone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineMesoridazine
Critical
How does the drug interact with Hansepran 100 Capsule:
When Hansepran 100 Capsule is taken with Mesoridazine, it can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Mesoridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDofetilide
Critical
How does the drug interact with Hansepran 100 Capsule:
When Hansepran 100 Capsule is taken with Dofetilide, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Dofetilide is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineThioridazine
Critical
How does the drug interact with Hansepran 100 Capsule:
When Hansepran 100 Capsule is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Thioridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineCisapride
Critical
How does the drug interact with Hansepran 100 Capsule:
When Hansepran 100 Capsule is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Cisapride is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDronedarone
Critical
How does the drug interact with Hansepran 100 Capsule:
When Hansepran 100 Capsule is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 100 Capsule with Dronedarone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineAlfuzosin
Severe
How does the drug interact with Hansepran 100 Capsule:
Co-administration of adenosine with Hansepran 100 Capsule can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenosine and Hansepran 100 Capsule can possibly result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
ClofazimineCholera, live attenuated
Severe
How does the drug interact with Hansepran 100 Capsule:
Co-administration of cholera, live attenuated with Hansepran 100 Capsule can decrease the effectiveness of cholera, live attenuated.

How to manage the interaction:
Co-administration of Hansepran 100 Capsule with Cholera, live attenuated can possibly result in an interaction, but it can be taken if your doctor has advised it. A minimum of 14 days following the last dose of your Hansepran 100 Capsule is the suggested duration to receive the cholera vaccine in order to guarantee a sufficient immune response. Do not discontinue any medications without consulting a doctor.
ClofazimineHalofantrine
Severe
How does the drug interact with Hansepran 100 Capsule:
Co-administration of halofantrine with Hansepran 100 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking halofantrine with Hansepran 100 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineHaloperidol
Severe
How does the drug interact with Hansepran 100 Capsule:
Co-administration of haloperidol with Hansepran 100 Capsule can increase the risk of irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking haloperidol with Hansepran 100 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Nov 18, 2025 | 7:26 AM IST

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