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Johnlee Metoclopramide Injection
Johnlee Metoclopramide Injection is an anti-emetic medication used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and post-operative conditions. It contains metoclopramide which increases the motility of the upper gastrointestinal tract and thus helps in gastric emptying. Some of the common side effects include fatigue, dizziness, headache, and bowel disturbances.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Johnlee Metoclopramide Injection
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drug-Drug Interactions

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MetoclopramideLurasidone
Critical
MetoclopramidePromethazine
Critical

Drug-Drug Interactions

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MetoclopramideLurasidone
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
The combination of Lurasidone and Johnlee Metoclopramide Injection may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Johnlee Metoclopramide Injection is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
MetoclopramidePromethazine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Johnlee Metoclopramide Injection is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideProchlorperazine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
MetoclopramideBupropion
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Bupropion can increase the levels of Johnlee Metoclopramide Injection and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Bupropion is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideNefazodone
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Nefazodone can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Nefazodone is generally avoided as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
MetoclopramideVenlafaxine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideFluvoxamine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Fluvoxamine with Johnlee Metoclopramide Injection increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Fluvoxamine with Johnlee Metoclopramide Injection is not recommended, as it can lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramideMaprotiline
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Maprotiline can increase the risk or severity of side effects.

How to manage the interaction:
Taking Maprotiline with Johnlee Metoclopramide Injection is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Consult your doctor if you see symptoms like dizziness, drowsiness, confusion, difficulty concentrating, or impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without consulting a doctor.
MetoclopramideTrazodone
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Trazodone can rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any symptoms like dizziness, fever, excessive sweating, shivering, blurred vision, muscle stiffness, stomach cramps, nausea, vomiting, or diarrhoea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideDuloxetine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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