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compositionComposition:KETOCONAZOLE-2%W/V
prescription
Prescription Medicine
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KZ Lotion 50 ml | Ketoconazole | For Fungal Skin Infection
KZ Lotion 50 ml | Ketoconazole | For Fungal Skin Infection

KZ Lotion 50 ml is used to treat fungal infections of the skin like ringworm, jock itch, athlete's foot, seborrheic dermatitis (dry, flaky skin on the face, scalp, chest, upper back or ears) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). It contains Ketoconazole which works by damaging the fungal cell membranes that are essential for their survival. Thus, it kills fungi and yeast. It may cause common side effects such as dry skin, itching, redness or burning sensation at the application site. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

KETOCONAZOLE-2%W/V

Manufacturer/Marketer :

Hegde & Hegde Pharmaceutica Llp

Consume Type :

Topical

Expires on or after :

Dec-26

Return Policy :

Not Returnable

About KZ Lotion 50 ml

KZ Lotion 50 ml is a topical antifungal medicine used to treat skin infections caused by fungi or yeast. It is commonly prescribed for skin conditions such as athlete's foot, jock itch, ringworm, sweat rash, and seborrheic dermatitis, which causes dry, flaky skin on your scalp or face.

To get the best results from your treatment, you must apply KZ Lotion 50 ml consistently and at the exact same times every day, even if your symptoms begin to clear up early. The medicine must be applied directly to the affected skin, which should be clean and completely dry before application. Making small lifestyle adjustments, such as wearing loose-fitting cotton clothes and drying your skin thoroughly after bathing, can help the treatment work more effectively.

While using KZ Lotion 50 ml , you may experience mild and temporary skin irritation, redness, or a slight burning sensation where the product is applied. These common side effects usually go away as your skin adjusts, but you should contact your doctor immediately if you experience severe burning, swelling, or blistering.

Do not use this medicine if you have open wounds, deep cuts, or severe skin damage at the application site. If you have any known allergies to other antifungal creams or skin products, talk to your doctor before starting KZ Lotion 50 ml to ensure it is safe for you to use.

Because KZ Lotion 50 ml is applied directly to the skin, very little of the medicine typically enters your bloodstream. However, absorption may increase when it is applied to large areas of skin, inflamed or damaged skin, or under airtight dressings. As a result, interactions with oral medicines are generally uncommon with topical use. However, if you are pregnant, planning to become pregnant, or breastfeeding, you should consult your doctor or pharmacist before using this treatment.

Uses of KZ Lotion 50 ml

Your doctor may prescribe KZ Lotion 50 ml to treat several types of fungal skin conditions. It is commonly used to treat:

  • Athlete's foot (tinea pedis): KZ Lotion 50 ml clears up the fungal infection between the toes, relieving itching, peeling, and burning.
  • Jock itch (tinea cruris): It targets fungal overgrowth in the groin area, soothing redness, chafing, and intense itching.
  • Ringworm (tinea corporis): It stops the spread of the circular, itchy rash on the body and helps the skin heal.
  • Seborrheic dermatitis and dandruff: It reduces yeast levels on the scalp and face, clearing up stubbornflakes, scaling, and redness.
  • Pityriasis versicolor: It helps restore natural skin tone by clearing the fungal patches that cause light or dark spots on the chest, back, or neck.
     

Key Benefits

KZ Lotion 50 ml brings real-world relief to uncomfortable and irritating skin conditions. By targeting the source of the fungal infection, it helps you feel better in several ways:

  • Quickly calms itching and discomfort: It rapidly soothes the intense itching and burning associated with fungal infections, allowing you to go about your day comfortably.
  • Restores skin health: It helps clear up embarrassing skin peeling, flaking, and redness, allowing your skin to heal and regain its natural texture.
  • Prevents the infection from spreading: Regular use stops the fungus from multiplying, which protects other parts of your body and prevents the infection from spreading to others.
     
Side effects of KZ Lotion 50 ml | Ketoconazole | For Fungal Skin Infection
  • Apply a cold compress to the irritated area can help reduce redness and swelling.
  • When applying medications that can cause irritation, switch up the application site each time to prevent excessive irritation in one area.
  • Using a gentle, fragrance-free moisturizer can help keep the skin hydrated and reduce irritation.
  • Wash the application site with mild soap and water before applying medication.
  • Scratching can worsen irritation, so try to avoid scratching.

Directions for Use

To get the safest and most effective results from KZ Lotion 50 ml , follow these step-by-step instructions and always use the product exactly as your doctor has instructed:

  • Wash your hands thoroughly with soap and water before applying the medicine.
  • Clean the affected skin area gently with mild soap and water, then pat it completely dry with a clean towel.
  • Apply a thin layer of KZ Lotion 50 ml to the affected area and slightly onto the surrounding healthy skin.
  • Gently rub the cream or gel in until it is evenly distributed and absorbed.
  • Wash your hands with soap and water immediately after application to avoid spreading the infection to other areas of your body or to other people.
  • Do not cover the treated area with bandages, tight dressings, or plastic wraps unless your doctor specifically tells you to do so.
     

How KZ Lotion 50 ml Works

The active ingredient in KZ Lotion 50 ml , ketoconazole, works by targeting the microscopic cells responsible for fungal infections. The active medicine interferes with the ability of the fungus to build its own cell walls. Specifically, it stops the production of a vital substance called ergosterol, which fungi need to keep their cell membranes intact. Without a stable cell membrane, holes develop in the outer layer of the fungal cells. This causes the internal contents of the cell to leak out, which effectively kills the fungus and stops the infection from multiplying. This process allows your skin's natural healing systems to repair the damage and clear the rash.
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Alcohol

Consult your doctor

Interaction of KZ Lotion 50 ml with alcohol is unknown. Please consult a doctor before consuming alcohol while using KZ Lotion 50 ml .

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Pregnancy

Consult your doctor

KZ Lotion 50 ml is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

KZ Lotion 50 ml is recommended for breastfeeding mothers only if needed. However, if KZ Lotion 50 ml is applied on the breast, care should be taken to avoid accidental ingestion by the baby.

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Driving

Safe if prescribed

KZ Lotion 50 ml usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of KZ Lotion 50 ml in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of KZ Lotion 50 ml in patients with kidney problems, please consult a doctor.

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Children

Unsafe

KZ Lotion 50 ml is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

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Heart

Consult your doctor

Please consult your doctor before using KZ Lotion 50 ml if you have pre-existing heart problems. Your doctor will prescribe KZ Lotion 50 ml if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving KZ Lotion 50 ml to geriatric patients. Your doctor will prescribe KZ Lotion 50 ml if the benefits outweigh the risks.

What if I have taken an overdose of KZ Lotion 50 ml

Do not apply KZ Lotion 50 ml in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects.

Diet & Lifestyle Advise

  • Keep the skin dry: Thoroughly dry your skin after showering or bathing, paying close attention to skin folds, the spaces between your toes, and your groin area.
  • Choose breathable clothing: Wear loose cotton clothing and cotton underwear. Avoid synthetic fabrics that trap moisture and sweat against your skin.
  • Avoid sharing personal items: Do not share towels, clothing, combs, hairbrushes, or footwear with others, as fungal spores can easily spread from person to person.
  • Manage sweat: Change out of sweaty gym clothes or wet swimwear as quickly as possible to prevent creating an ideal environment for fungi to grow.
  • Wash linens frequently: Wash your towels, bed sheets, and socks in hot water regularly to kill any lingering fungal spores.
     

Health Queries

I keep getting dandruff again and again, and even after using KZ lotion, the problem is still not improving properly. Is there any other treatment that may work better for me?

Veda Maddala

Veda Maddala

M Pharmacy

If dandruff keeps coming back even after using KZ lotion, it usually means the scalp problem is more long-term, like seborrheic dermatitis. In this condition, oil, normal skin yeast, and scalp sensitivity keep triggering flakes and itching again and again, so a single lotion may only give temporary relief. Things like stress, sweating, weather changes, and frequent oiling can also make it flare repeatedly. In such cases, treatment often works better when it is consistent rather than one-time. Medicated shampoos like ketoconazole, zinc pyrithione, or selenium sulfide are commonly used on a regular schedule and then continued weekly as maintenance even after improvement. Sometimes doctors also add scalp lotions or short courses of soothing or anti-inflammatory medicines if itching and redness are more active. Keeping the scalp clean, washing off sweat, and avoiding heavy oiling during flare-ups can help reduce recurrence. If there is still no proper improvement despite regular care, it is better to see a dermatologist again, because a few other conditions, like psoriasis, can look similar and may need a different treatment approach.

I have been suffering from dandruff for nearly 10 years, and even after using KZ lotion prescribed by my doctor, the problem keeps coming back. Is there any long-term solution that may help control it better?

Veda Maddala

Veda Maddala

M Pharmacy

Dandruff that has been going on for years usually behaves more like a long-term scalp condition rather than something that can be fully cured with a short course of treatment. In most cases, it is related to seborrheic dermatitis, where scalp oil, natural yeast, and sensitivity of the skin keep triggering repeated itching and flaking. That is why medicines like KZ lotion may work for a while, but the problem tends to come back once they are stopped or used less frequently. Things like stress, sweating, seasonal changes, and heavy oiling can also make it flare again. For better control, it usually needs a maintenance routine instead of only treating during flare-ups. Medicated shampoos or lotions such as ketoconazole, zinc-based, or selenium-based products are often continued weekly or a few times a week even after improvement. Keeping the scalp clean, avoiding leaving oil for long hours during active dandruff, and washing after sweating can also reduce recurrence. If the problem is still returning despite regular care, it is better to get re-evaluated by a dermatologist, as sometimes other conditions like psoriasis can look similar and may need a different treatment approach.

Have a query?

How Soon It Starts Working

  • The time required for KZ Lotion 50 ml to start to work: The time required for KZ Lotion 50 ml to show its action is unknown.
  • The time for which the effects of KZ Lotion 50 ml last: The duration of action for KZ Lotion 50 ml is unknown.

What if you forget to take KZ Lotion 50 ml

Apply the missed dose as soon as you can. If it is almost time for the next dose, skip the missed dose and follow your regular schedule.

Storage

Store the medicine at room temperature, ideally between 15°C and 30°C. Do not freeze the product. •Keep the tube or bottle tightly closed when you are not using it to prevent contamination.

Drug Warnings

  • Avoid Contact with Eyes and Mouth: Apply KZ Lotion 50 ml only to the affected skin or scalp. If it accidentally gets into your eyes, nose, or mouth, rinse thoroughly with plenty of cool water.
  • Complete the Full Course: Continue using KZ Lotion 50 ml for the full duration prescribed by your doctor, even if your symptoms improve or disappear earlier.
  • Check Before Use: Inspect the tube or bottle before use. Do not use the product if the packaging is damaged or if the cream has changed colour or developed an unusual odour.
  • Avoid Using Other Topical Products: Do not apply other medicated creams, ointments, or cosmetic products to the same treated area unless advised by your doctor.
  • Use Only as Directed: Avoid applying KZ Lotion 50 ml to large areas of damaged skin or covering the treated area with airtight dressings unless specifically instructed by your doctor. 
     

Drug-Drug Interactions

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Drug-Drug Interactions

The following products may interact with topical KZ Lotion 50 ml and may require special precautions:

  • Topical steroids and other skin treatments: If you are using steroid creams, medicated lotions, or other topical treatments on the same area of skin, tell your doctor. They will advise you on the safest way to use these products together and help minimise irritation. 

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before using KZ Lotion 50 ml , as they may require special precautions:

  • Severe skin conditions: If you have active eczema, psoriasis, or highly sensitive skin, using KZ Lotion 50 ml may cause temporary irritation or localised burning. Talk to your doctor before starting treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Therapeutic Class

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Reference

  1. Drugs.com Clinical Review Team. Ketoconazole Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 021946S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Ketoconazole cream [Prescribing Information]. 2014. [Accessed on 10 Jun. 2025] Check here
  4. Ketoconazole [Summary of Product Characteristics]. 2023. [Accessed on 10 Jun. 2025] Check here
  5. Ketoconazole Ketoconazole. 2026. [Accessed on 01 Apr. 2026] Check here
  6. Ketoconazole 2% w/w Shampoo - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 31 Oct 2025] Check here
  7. Ketoconazole (Topical Route) Description and Brand Names - Mayo Clinic [Internet]. Mayoclinic.org. 2021 [Accessed on 31 Oct 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Office No. 11A ? 15, 1st Floor, Free Press House, 215, Nariman Point, Mumbai ? 400 021
Other Info - KZ50001

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