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जनवरी-25
Drug-Drug Interactions
NorfloxacinBepridil
Critical
Critical
Drug-Drug Interactions
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NorfloxacinBepridil
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Using bepridil together with Loc 400 mg/600 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
Using bepridil together with Loc 400 mg/600 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Coadministration of Loc 400 mg/600 mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Coadministration of Loc 400 mg/600 mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Coadministration of Loc 400 mg/600 mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Coadministration of Loc 400 mg/600 mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Coadministration of Loc 400 mg/600 mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
Coadministration of Loc 400 mg/600 mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Using Mesoridazine together with Loc 400 mg/600 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Mesoridazine with Loc 400 mg/600 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Using Mesoridazine together with Loc 400 mg/600 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Mesoridazine with Loc 400 mg/600 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
The combination of Amiodarone and Loc 400 mg/600 mg Tablet may significantly raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Despite the fact that Amiodarone and Loc 400 mg/600 mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
The combination of Amiodarone and Loc 400 mg/600 mg Tablet may significantly raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Despite the fact that Amiodarone and Loc 400 mg/600 mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
TinidazoleAmprenavir
Critical
How does the drug interact with Loc 400 mg/600 mg Tablet:
Co-administration of Amprenavir and Loc 400 mg/600 mg Tablet can increase the risk or severity of developing serious side effects.
How to manage the interaction:
Co-administration of Amprenavir and Loc 400 mg/600 mg Tablet is generally avoided, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like flushing, severe headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, excessive sweating, dizziness, lightheadedness, blurred vision, or confusion. Rarely, more severe reactions may include unconsciousness or convulsions, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Co-administration of Amprenavir and Loc 400 mg/600 mg Tablet can increase the risk or severity of developing serious side effects.
How to manage the interaction:
Co-administration of Amprenavir and Loc 400 mg/600 mg Tablet is generally avoided, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like flushing, severe headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, excessive sweating, dizziness, lightheadedness, blurred vision, or confusion. Rarely, more severe reactions may include unconsciousness or convulsions, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
NorfloxacinMetrizamide
Severe
How does the drug interact with Loc 400 mg/600 mg Tablet:
Coadministration of Loc 400 mg/600 mg Tablet with Metrizamide may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).
How to manage the interaction:
Although there is a possible interaction between Loc 400 mg/600 mg Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
Coadministration of Loc 400 mg/600 mg Tablet with Metrizamide may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).
How to manage the interaction:
Although there is a possible interaction between Loc 400 mg/600 mg Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Loc 400 mg/600 mg Tablet:
Coadministration of Bupropion with Loc 400 mg/600 mg Tablet may enhance the risk or severity seizure (fits).
How to manage the interaction:
Co-administration of bupropion along with Loc 400 mg/600 mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
Coadministration of Bupropion with Loc 400 mg/600 mg Tablet may enhance the risk or severity seizure (fits).
How to manage the interaction:
Co-administration of bupropion along with Loc 400 mg/600 mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Loc 400 mg/600 mg Tablet:
Co-administration of Loc 400 mg/600 mg Tablet with Methylprednisolone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Methylprednisolone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Loc 400 mg/600 mg Tablet with Methylprednisolone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).
How to manage the interaction:
Taking Loc 400 mg/600 mg Tablet with Methylprednisolone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods
Drug-Food Interactions
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NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt
How to manage the interaction:
Consumption of food containing minerals like magnesium, zinc, and calcium reduces the absorption of Tinidazole and Norfloxacin, resulting in reduced medication efficacy in treating infections. It is advised to take Tinidazole and Norfloxacin on an empty stomach and to avoid consuming food or products containing minerals one hour before and 2 hours after consuming Tinidazole and Norfloxacin.
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt
How to manage the interaction:
Consumption of food containing minerals like magnesium, zinc, and calcium reduces the absorption of Tinidazole and Norfloxacin, resulting in reduced medication efficacy in treating infections. It is advised to take Tinidazole and Norfloxacin on an empty stomach and to avoid consuming food or products containing minerals one hour before and 2 hours after consuming Tinidazole and Norfloxacin.
Product Substitutes
शराब
Unsafe
लोक 400 एमजी/600 एमजी टैबलेट को शराब के साथ नहीं लिया जाना चाहिए क्योंकि यह पेट में जलन पैदा कर सकता है।
गर्भावस्था
Caution
सावधानी बरती जानी चाहिए, इसका उपयोग करने से पहले डॉक्टर से परामर्श करना उचित है।
स्तनपान
Safe if prescribed
लोक 400 एमजी/600 एमजी टैबलेट स्तन के दूध के माध्यम से बच्चे तक महत्वपूर्ण रूप से नहीं पहुंचता है, इसलिए इसका उपयोग करने से पहले डॉक्टर से परामर्श करना उचित है।
ड्राइविंग
Caution
लोक 400 एमजी/600 एमजी टैबलेट से चक्कर आना और दृष्टि संबंधी समस्याएं हो सकती हैं। इसलिए, केवल तभी गाड़ी चलाएं जब आप सतर्क हों।
जिगर
Caution
लोक 400 एमजी/600 एमजी टैबलेट सावधानी के साथ लिया जाना चाहिए, खासकर अगर आपको लिवर की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जाना पड़ सकता है।
किडनी
Caution
लोक 400 एमजी/600 एमजी टैबलेट सावधानी के साथ लिया जाना चाहिए, खासकर अगर आपको किडनी की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जाना पड़ सकता है।
बच्चे
Caution
लोक 400 एमजी/600 एमजी टैबलेट को डॉक्टर की सहमति के बिना 12 वर्ष से कम उम्र के बच्चों के लिए अनुशंसित नहीं किया जाता है। 12 वर्ष से अधिक उम्र के बच्चों के लिए, खुराक को केवल बाल रोग विशेषज्ञ द्वारा समायोजित और अनुशंसित किया जाना चाहिए।
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