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Methergin Tablet 10's
Methergin Tablet 10's
Methergin Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Methergin Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug-Drug Interactions

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MethylergometrineClarithromycin
Critical
MethylergometrineSumatriptan
Critical

Drug-Drug Interactions

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MethylergometrineClarithromycin
Critical
How does the drug interact with Methergin Tablet:
When Methergin Tablet is taken with Clarithromycin, the amount of Methergin Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methergin Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Sumatriptan with Methergin Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methergin Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Glyceryl trinitrate can increase the levels and side effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Methergin Tablet:
Taking Methergin Tablet with Ritonavir can significantly increase the blood levels and effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet:
Using Ketoconazole with Methergin Tablet can increase the concentration of Methergin Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Voriconazole may increase the blood level of Methergin Tablet.

How to manage the interaction:
Although Methergin Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methergin Tablet:
Co-administration of Methergin Tablet and Itraconazole may increase the blood levels of Methergin Tablet.

How to manage the interaction:
Methergin Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methergin Tablet:
Taking Phenylephrine with Methergin Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methergin Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.
MethylergometrineEphedrine
Severe
How does the drug interact with Methergin Tablet:
Taking Ephedrine with Methergin Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methergin Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methergin Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methergin Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methergin Tablet. This can increase the risk or severity of side effects.

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