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संघटन :
मेथोट्रेक्सेट-25एमजी
निर्माता/विपणक :
इप्का लैबोरेटरीज लिमिटेड
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आंत्रेतर
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Jan-27
Drug-Drug Interactions
MethotrexateEtretinate
Critical
MethotrexatePhenylbutazone
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Etretinate with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methorapfs 20 Injection 0.4 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methorapfs 20 Injection 0.4 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexatePhenylbutazone
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of phenylbutazone with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of phenylbutazone with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Methorapfs 20 Injection 0.4 ml with dicloxacillin can increase the levels and effects of Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of serious infections.
How to manage the interaction:
Although there is a possible interaction between Methorapfs 20 Injection 0.4 ml and dicloxacillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Methorapfs 20 Injection 0.4 ml with dicloxacillin can increase the levels and effects of Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of serious infections.
How to manage the interaction:
Although there is a possible interaction between Methorapfs 20 Injection 0.4 ml and dicloxacillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Baricitinib and Methorapfs 20 Injection 0.4 ml can increase the risk or severity of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Baricitinib and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination. Consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Baricitinib and Methorapfs 20 Injection 0.4 ml can increase the risk or severity of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Baricitinib and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination. Consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of Mefenamic acid with Methorapfs 20 Injection 0.4 ml may increase the blood levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between mefenamic acid and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of Mefenamic acid with Methorapfs 20 Injection 0.4 ml may increase the blood levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between mefenamic acid and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Combine use of tenofovir alafenamide with Methorapfs 20 Injection 0.4 ml may increase the levels or side effects of tenofovir alafenamide.
How to manage the interaction:
Although there is a possible interaction between tenofovir alafenamide and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
Combine use of tenofovir alafenamide with Methorapfs 20 Injection 0.4 ml may increase the levels or side effects of tenofovir alafenamide.
How to manage the interaction:
Although there is a possible interaction between tenofovir alafenamide and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
MethotrexateProcaine benzylpenicillin
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of Methorapfs 20 Injection 0.4 ml with procaine benzyl penicillin can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between procaine benzyl penicillin and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms, consult your doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Methorapfs 20 Injection 0.4 ml with procaine benzyl penicillin can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between procaine benzyl penicillin and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms, consult your doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Methorapfs 20 Injection 0.4 ml with pantoprazole can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Methorapfs 20 Injection 0.4 ml with pantoprazole can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Methorapfs 20 Injection 0.4 ml with amoxicillin can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between Methorapfs 20 Injection 0.4 ml and amoxicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Methorapfs 20 Injection 0.4 ml with amoxicillin can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between Methorapfs 20 Injection 0.4 ml and amoxicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Taking deferasirox with Methorapfs 20 Injection 0.4 ml may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking deferasirox with Methorapfs 20 Injection 0.4 ml may increase the risk of kidney damage.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
METHOTREXATE-20MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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METHOTREXATE-20MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Methorapfs 20 Injection 0.4 ml. Avoid taking caffeine while taking Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of side effects.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Methorapfs 20 Injection 0.4 ml. Avoid taking caffeine while taking Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of side effects.
Methorapfs 20 Injection 0.4 ml Substitute
Product Substitutes
शराब
Unsafe
आपको Methorapfs 20 Injection 0.4 ml लेते समय शराब के सेवन से बचने की सलाह दी जाती है।
गर्भावस्था
Unsafe
Methorapfs 20 Injection 0.4 ml से गंभीर जन्म दोष हो सकते हैं। गर्भवती होने पर Methorapfs 20 Injection 0.4 ml लेने की अनुशंसा नहीं की जाती है।
स्तनपान
Unsafe
Methorapfs 20 Injection 0.4 ml स्तन के दूध में चला जाता है। Methorapfs 20 Injection 0.4 ml के साथ उपचार के दौरान और अंतिम खुराक के कम से कम 1 सप्ताह बाद तक स्तनपान कराने से बचें।
ड्राइविंग
Caution
Methorapfs 20 Injection 0.4 ml के कारण चक्कर आना और थकान हो सकती है; जब तक आप यह न जान लें कि Methorapfs 20 Injection 0.4 ml का आप पर क्या प्रभाव पड़ता है, तब तक वाहन न चलाएं या भारी मशीनरी का संचालन न करें।
जिगर
Caution
यदि आपको यकृत की समस्या है तो कृपया Methorapfs 20 Injection 0.4 ml लेने से पहले अपने चिकित्सक से परामर्श करें।
किडनी
Caution
यदि आपको गुर्दे की समस्या है तो कृपया Methorapfs 20 Injection 0.4 ml लेने से पहले अपने चिकित्सक से परामर्श करें।
बच्चे
Caution
बच्चों में Methorapfs 20 Injection 0.4 ml की प्रभावकारिता और सुरक्षा पॉलीआर्टिकुलर-कोर्स जुवेनाइल रूमेटोइड गठिया और कैंसर कीमोथेरेपी में स्थापित की गई है। अगर आपको बच्चों में Methorapfs 20 Injection 0.4 ml के उपयोग के बारे में कोई चिंता है, तो कृपया अपने डॉक्टर से परामर्श करें।
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