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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Norflox 400 Tablet is used to treat bacterial infections. It contains Norfloxacin and Lactic acid bacillus. Norfloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Lactic acid bacillus is a probiotic (live bacteria with health benefits) that restores good bacteria in the gut.

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Side effects of Norflox 400 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
NorfloxacinMesoridazine
Critical

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
How does the drug interact with Norflox 400 Tablet:
Using bepridil together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Norflox 400 Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Norflox 400 Tablet:
Using Mesoridazine together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Norflox 400 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norflox 400 Tablet:
The combination of Amiodarone and Norflox 400 Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Norflox 400 Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Papaverine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Papaverine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Taking insulin glulisine with Norflox 400 Tablet affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Norflox 400 Tablet and Insulin glulisine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
NorfloxacinDolasetron
Severe
How does the drug interact with Norflox 400 Tablet:
Using Dolasetron together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Norflox 400 Tablet with Dolasetron can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like an irregular heartbeat, a heart condition, or any of the other symptoms mentioned, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Iohexol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Norflox 400 Tablet with Iohexol together can result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Norflox 400 Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Norflox 400 Tablet may increase the effects of caffeine. Norflox 400 Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Norflox 400 Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

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