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NORGEST TABLET is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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NorethisteroneBexarotene
Severe

Drug-Drug Interactions

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NorethisteroneBexarotene
Severe
How does the drug interact with Norgest Tablet:
Coadministration of Bexarotene and Norgest Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Norgest Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norgest Tablet:
Coadministration of Phenytoin and Norgest Tablet may decrease the blood levels of Norgest Tablet, which may make Norgest Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Norgest Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norgest Tablet:
Coadministration of Norgest Tablet with Oxcarbazepine can reduce the blood levels and effects of norethindrone. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking oxcarbazepine and Norgest Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately Do not discontinue any medications without consulting a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Norgest Tablet:
Coadministration of Amprenavir and Norgest Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Norgest Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norgest Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Norgest Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Norgest Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Norgest Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Norgest Tablet:
Using Felbamate and Norgest Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Norgest Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norgest Tablet:
Eslicarbazepine may reduce the effects of Norgest Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Norgest Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Norgest Tablet:
Co-administration of Norgest Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Norgest Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norgest Tablet:
Taking carbamazepine and Norgest Tablet may possibly reduce the effects of Norgest Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Norgest Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Norgest Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Norgest Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Norgest Tablet dose.

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