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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Oloplus KT Eye Drop 5 ml is used to treat allergic eye disease. It contains Ketorolac and Olopatadine, which works by blocking the release of several chemical messengers that cause inflammation (redness and swelling), and pain in the eye. It may cause side effects such as burning sensation, eye pain, eye discomfort, eye irritation, headache, dry nose, and taste change. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Oloplus KT Eye Drop 5 ml:
Using Oloplus KT Eye Drop 5 ml together with piroxicam may increase the risk of side effects.

How to manage the interaction:
Taking Piroxicam with Oloplus KT Eye Drop 5 ml is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Taking Ketorolac with Celecoxib can increase the risk of gastrointestinal bleeding and ulcers,

How to manage the interaction:
Taking Oloplus KT Eye Drop 5 ml with Celecoxib is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Taking Ketorolac with Flurbiprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Flurbiprofen with Oloplus KT Eye Drop 5 ml is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Combining Oloplus KT Eye Drop 5 ml with Aspirin can increase the risk of adverse effects.

How to manage the interaction:
Taking Aspirin with Oloplus KT Eye Drop 5 ml is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
OlopatadineSodium oxybate
Severe
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Using sodium oxybate together with Oloplus KT Eye Drop 5 ml nasal may increase the side effects

How to manage the interaction:
Although there is a possible interaction between Oloplus KT Eye Drop 5 ml and Sodium oxybate, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Using Oloplus KT Eye Drop 5 ml together with citalopram enhances drowsiness, and raises the likelihood of depressed feelings, which can decrease mental and physical abilities and interfere with daily functioning.

How to manage the interaction:
Although there is a possible interaction between Oloplus KT Eye Drop 5 ml and Citalopram, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
Co-administration Oloplus KT Eye Drop 5 ml and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Even though combining Oloplus KT Eye Drop 5 ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Oloplus KT Eye Drop 5 ml:
The combined use of Oloplus KT Eye Drop 5 ml and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Oloplus KT Eye Drop 5 ml and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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KETOROLAC-0.4%W/V+OLOPATADINE-0.1%W/VFruit juices, Fruits
Moderate

Drug-Food Interactions

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KETOROLAC-0.4%W/V+OLOPATADINE-0.1%W/VFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Coadministration of Oloplus KT Eye Drop 5 ml along with grapefruit or grapefruit juice may increase the blood levels of Oloplus KT Eye Drop 5 ml. This may increase the risk and/or severity of side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, and yellowing of the skin or eyes. Avoid the consumption of grapefruit juice with Oloplus KT Eye Drop 5 ml, as it can increase the risk of side effects.

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