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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Onglyza 2.5 mg Tablet is used in the treatment of type 2 diabetes in adults when diet and exercise alone cannot control blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. It contains Saxagliptin, which increases insulin production after meals when blood sugar is high. It may cause common side effects such as hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Drug-Drug Interactions

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SaxagliptinBexarotene
Severe

Drug-Drug Interactions

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How does the drug interact with Onglyza 2.5 mg Tablet:
Coadministration of Onglyza 2.5 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Onglyza 2.5 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the doctor if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, urination, thirst, and hunger. Monitoring blood glucose levels is advised. Do not discontinue any medications without first consulting your doctor.
SaxagliptinBexarotene
Severe
How does the drug interact with Onglyza 2.5 mg Tablet:
Coadministration of Bexarotene and Onglyza 2.5 mg Tablet can increase the risk of developing pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Bexarotene and Onglyza 2.5 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SaxagliptinTirzepatide
Moderate
How does the drug interact with Onglyza 2.5 mg Tablet:
As tirzepatide and Onglyza 2.5 mg Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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