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Drug-Drug Interaction: Pedicloryl Syrup may have interaction with high blood pressure-lowering medicines (metoprolol), opioid pain killers (hydrocodone, oxycodone, naloxone, tramadol), antidepressants (sertraline, desipramine, fluoxetine, venlafaxine, bupropion, fluvoxamine, escitalopram, amitriptyline, citalopram, duloxetine, mirtazapine), antibiotics (ciprofloxacin, rifampicin), antifungal drugs (ketoconazole), anti-anxiety drugs (alprazolam, clonazepam, lorazepam), antiallergics/antihistamines (diphenhydramine, hydroxyzine), muscle relaxants (cyclobenzaprine), and antiepileptic drugs (gabapentin, pregabalin).
Drug-Food Interaction: Pedicloryl Syrup may interact with caffeine, St John’s wort (herbal medicine for treating depression) and may reduce the effectiveness of Pedicloryl Syrup. Also, avoid alcohol intake as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleepwalking, or sleep-driving.
Drug-Disease Interaction: Do not take Pedicloryl Syrup if you have severe liver disease, breathing problems, sleep apnoea (sudden stopping of breathing during sleep), severe muscle weakness, kidney problems, and any history of depression or mental illness.
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