Pegihep 100 Injection 1's

Prescription drug

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MRP ₹7084.5

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pegihep 100 Injection is used to treat Chronic (long-term) hepatitis C infection. It contains Peginterferon alpha-2b, which works by decreasing the amount of hepatitis C virus (HCV) in the body. In some cases, Pegihep 100 Injection may cause side effects such as injection site reactions, breathing problems (including shortness of breath), feeling depressed, trouble sleeping, thinking, or concentrating, dizziness, severe stomach pain or cramps, fever or chills, and painful or inflamed muscles (sometimes severe).

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Side effects of Pegihep 100 Injection

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Mood Swings

Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
Consult your doctor if the mood swings are uncontrollable or unmanageable.

Depression

Managing depression as a side effect of medication: a comprehensive guide.

Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
Tell your doctor about your depression symptoms to adjust medication.
Consult a therapist or counsel for emotional support.
Engage in regular exercise to release endorphins (neurotransmitters).
Practice stress-reducing techniques like meditation and deep breathing.
Build a support network of friends, family, and support groups.
Establish a consistent sleep schedule.
Eat a nutritious diet rich in fruits, vegetables, and whole grains.
Limit or avoid alcohol and recreational substances.
Keep a mood journal to track symptoms and progress.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

High Alanine Aminotransferase Levels

To improve liver health and aid in the removal of toxins, drink lots of water.
Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Drug-Drug Interactions

Peginterferon alfa-2bCladribine

Severe

Peginterferon alfa-2bEltrombopag

Severe

Drug-Drug Interactions

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Peginterferon alfa-2bCladribine

Severe

How does the drug interact with Pegihep 100 Injection:
Taking Pegihep 100 Injection with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladribine and Pegihep 100 Injection, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Peginterferon alfa-2bEltrombopag

Severe

How does the drug interact with Pegihep 100 Injection:
When Eltrombopag is combined with Pegihep 100 Injection the serum concentration of Eltrombopag can be increased.

How to manage the interaction:
Although taking Eltrombopag and Pegihep 100 Injection together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to call your doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Don't hesitate to reach out to a doctor if you have concerns about your health. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Keep Refrigerated. Do not freeze.

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 22, 2025 | 7:26 AM IST

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