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Phytoral Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Side effects of Phytoral Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug-Drug Interactions

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KetoconazoleNisoldipine
Critical

Drug-Drug Interactions

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How does the drug interact with Phytoral Tablet:
Using colchicine together with Phytoral Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Phytoral Tablet with Colchicine is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
KetoconazoleNisoldipine
Critical
How does the drug interact with Phytoral Tablet:
When Nisoldipine is taken with Phytoral Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure).

How to manage the interaction:
Taking Phytoral Tablet with Nisoldipine can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure while using these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleDofetilide
Critical
How does the drug interact with Phytoral Tablet:
When Dofetilide is taken with Phytoral Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Phytoral Tablet with Dofetilide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Phytoral Tablet:
Using Phytoral Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.

How to manage the interaction:
Taking Phytoral Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Phytoral Tablet:
When Pimozide is taken with Phytoral Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Phytoral Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Phytoral Tablet:
Coadministration of Lovastatin with Phytoral Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Phytoral Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Phytoral Tablet:
Using irinotecan together with Phytoral Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Phytoral Tablet with Irinotecan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.
KetoconazoleConivaptan
Critical
How does the drug interact with Phytoral Tablet:
Using conivaptan together with Phytoral Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Phytoral Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Phytoral Tablet:
When Dronedarone is taken with Phytoral Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Phytoral Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Phytoral Tablet:
When Regorafenib is taken with Phytoral Tablet, it can increase the levels of Regorafenib, which may lead to side effects.

How to manage the interaction:
Taking Regorafenib with Phytoral Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Phytoral Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Phytoral Tablet.

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