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Polynex Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polynex Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Inform the doctor if you are taking medicines that cause kidney or nerve problems.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have kidney or nerve problems.

Drug-Drug Interactions

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How does the drug interact with Polynex Injection:
Co-administration of Polynex Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polynex Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Polynex Injection:
Taking Adefovir dipivoxil with Polynex Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Polynex Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Polynex Injection:
Taking Tobramycin with Polynex Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polynex Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Polynex Injection:
Co-administration of Polynex Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Polynex Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Polynex Injection:
Co-administration of Polynex Injection and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Polynex Injection with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Polynex Injection:
Using Polynex Injection together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Polynex Injection and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Polynex Injection:
Taking Tenofovir alafenamide with Polynex Injection can increase the chance of side effects.

How to manage the interaction:
Taking Tenofovir alafenamide with Polynex Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Polynex Injection:
Taking Cidofovir with Polynex Injection sulfate can increase the risk of kidney problems.

How to manage the interaction:
Although taking Polymyxin-b and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Polynex Injection:
Taking Kanamycin with Polynex Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Polynex Injection and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Polynex Injection:
When the BCG vaccine is used with Polynex Injection, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Polynex Injection and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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