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Samluta 40mg Capsule

Samluta 40mg Capsule is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Samluta 40mg Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.

Drug-Drug Interactions

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EnzalutamideRanolazine
Critical
EnzalutamideDronedarone
Critical

Drug-Drug Interactions

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EnzalutamideRanolazine
Critical
How does the drug interact with Samluta 40mg Capsule:
Taking Samluta 40mg Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Samluta 40mg Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideDronedarone
Critical
How does the drug interact with Samluta 40mg Capsule:
Co-administration of Samluta 40mg Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Samluta 40mg Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Samluta 40mg Capsule:
Taking Samluta 40mg Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Samluta 40mg Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideLurasidone
Critical
How does the drug interact with Samluta 40mg Capsule:
Co-administration of Lurasidone with Samluta 40mg Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Samluta 40mg Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideRegorafenib
Critical
How does the drug interact with Samluta 40mg Capsule:
Taking Samluta 40mg Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Samluta 40mg Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideGatifloxacin
Severe
How does the drug interact with Samluta 40mg Capsule:
Taking Samluta 40mg Capsule and Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Samluta 40mg Capsule and Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideDolasetron
Severe
How does the drug interact with Samluta 40mg Capsule:
Taking Samluta 40mg Capsule and Dolasetron together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Samluta 40mg Capsule and Dolasetron together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideGefitinib
Severe
How does the drug interact with Samluta 40mg Capsule:
Coadministration of Gefitinib with Samluta 40mg Capsule can alter the blood levels of Gefitinib which can lead to poor treatment outcomes.

How to manage the interaction:
Taking Gefitinib with Samluta 40mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
EnzalutamideOlaparib
Severe
How does the drug interact with Samluta 40mg Capsule:
Co-administration of Samluta 40mg Capsule and Olaparib may decrease the blood levels of Olaparib, which may make Olaparib less effective in treating your condition.

How to manage the interaction:
Although taking Samluta 40mg Capsule and Olaparib together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideImatinib
Severe
How does the drug interact with Samluta 40mg Capsule:
Taking Imatinib and Samluta 40mg Capsule together may possibly reduce the blood levels of Imatinib, which could reduce its capacity to treat cancer.

How to manage the interaction:
Although there is a possible interaction between Samluta 40mg Capsule and Imatinib, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's Wort products during Samluta 40mg Capsule treatment may lead to decrease in the effectiveness of Samluta 40mg Capsule. Avoid St. John's Wort products during Samluta 40mg Capsule treatment

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