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Satrogyl-O Dry Syrup is used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients. It contains two antibiotic medicines, namely: Ofloxacin and Satranidazole, which kill harmful bacteria and parasites (amoebae). In some cases, it may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, dizziness, and headaches. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Side effects of Satrogyl-O Dry Syrup 60 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

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Drug-Drug Interactions

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Drug-Drug Interaction: Satrogyl-O Dry Syrup may interact with blood thinners (such as acenocoumarol and warfarin), painkillers (such as aspirin), herbal products (such as ginkgo), respiratory drugs (such as albuterol), and medications used to treat alcohol addiction (such as disulfiram).

Drug-Food Interaction: The consumption of alcoholic beverages should be avoided as it may lead to flushing, drowsiness, and dizziness.

Drug-Disease Interaction: Inform your doctor before starting Satrogyl-O Dry Syrup if you have liver or kidney diseases, tendonitis, fits, blood dyscrasia, colitis, diabetes, myasthenia gravis, dehydration, dialysis, high blood pressure, nerve problems, and mental/mood disorders (depression).

Critical

Drug-Drug Interactions

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How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Thioridazine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Thioridazine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Saquinavir with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Saquinavir with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Pimozide with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Pimozide with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Amiodarone with Satranidazole and Ofloxacin can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Amiodarone with Satranidazole and Ofloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Ziprasidone with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Ziprasidone with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Dronedarone with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Dronedarone with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Quinidine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Quinidine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Bepridil with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Bepridil with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Mesoridazine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Mesoridazine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Satrogyl-O Dry Syrup 60 ml:
Co-administration of Disopyramide with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Disopyramide with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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OFLOXACIN-50MG/5ML+SATRANIDAZOLE-75MG/5MLCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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OFLOXACIN-50MG/5ML+SATRANIDAZOLE-75MG/5MLCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin can lead to decrease in blood levels of Ofloxacin. Avoid or limit consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin.

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