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Drug-Drug Interactions
Critical
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Coadministration of ketorolac together with Spifen MR 50mg/4mg Tablet may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulcers.
How to manage the interaction:
Taking Ketorolac with Spifen MR 50mg/4mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Coadministration of ketorolac together with Spifen MR 50mg/4mg Tablet may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulcers.
How to manage the interaction:
Taking Ketorolac with Spifen MR 50mg/4mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Coadministration of Piroxicam with Spifen MR 50mg/4mg Tablet can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.
How to manage the interaction:
Although there is a possible interaction between Piroxicam and Spifen MR 50mg/4mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Piroxicam with Spifen MR 50mg/4mg Tablet can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.
How to manage the interaction:
Although there is a possible interaction between Piroxicam and Spifen MR 50mg/4mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Taking Spifen MR 50mg/4mg Tablet with Prasugrel can increase the risk of bleeding and hemorrhage.
How to manage the interaction:
There may be a possibility of interaction between Prasugrel and Spifen MR 50mg/4mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Spifen MR 50mg/4mg Tablet with Prasugrel can increase the risk of bleeding and hemorrhage.
How to manage the interaction:
There may be a possibility of interaction between Prasugrel and Spifen MR 50mg/4mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Co-administration of Meloxicam with Spifen MR 50mg/4mg Tablet can increase the risk of side effects.
How to manage the interaction:
Although taking Meloxicam and Spifen MR 50mg/4mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like inflammation, bleeding, or stomach problems, unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Meloxicam with Spifen MR 50mg/4mg Tablet can increase the risk of side effects.
How to manage the interaction:
Although taking Meloxicam and Spifen MR 50mg/4mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like inflammation, bleeding, or stomach problems, unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Taking Spifen MR 50mg/4mg Tablet with Glimepiride may increase the risk of hypoglycemia (low blood sugar).
How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Spifen MR 50mg/4mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
Taking Spifen MR 50mg/4mg Tablet with Glimepiride may increase the risk of hypoglycemia (low blood sugar).
How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Spifen MR 50mg/4mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Coadministration of Spifen MR 50mg/4mg Tablet and Tenofovir disoproxil can increase the risk of developing kidney problems.
How to manage the interaction:
Taking Spifen MR 50mg/4mg Tablet and Tenofovir disoproxil together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Coadministration of Spifen MR 50mg/4mg Tablet and Tenofovir disoproxil can increase the risk of developing kidney problems.
How to manage the interaction:
Taking Spifen MR 50mg/4mg Tablet and Tenofovir disoproxil together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Coadministration of Spifen MR 50mg/4mg Tablet and Apixaban co-administration may raise the risk of bleeding.
How to manage the interaction:
Even though combining Spifen MR 50mg/4mg Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
Coadministration of Spifen MR 50mg/4mg Tablet and Apixaban co-administration may raise the risk of bleeding.
How to manage the interaction:
Even though combining Spifen MR 50mg/4mg Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Taking Spifen MR 50mg/4mg Tablet with etodolac may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases perforation).
How to manage the interaction:
Co-administration of Etodolac with Spifen MR 50mg/4mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Spifen MR 50mg/4mg Tablet with etodolac may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases perforation).
How to manage the interaction:
Co-administration of Etodolac with Spifen MR 50mg/4mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Coadministration of Naproxen and Spifen MR 50mg/4mg Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Naproxen and Spifen MR 50mg/4mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Coadministration of Naproxen and Spifen MR 50mg/4mg Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Naproxen and Spifen MR 50mg/4mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Spifen MR 50mg/4mg Tablet:
Taking Human immunoglobulin with Spifen MR 50mg/4mg Tablet, may raise the risk of kidney problems.
How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Spifen MR 50mg/4mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Taking Human immunoglobulin with Spifen MR 50mg/4mg Tablet, may raise the risk of kidney problems.
How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Spifen MR 50mg/4mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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शराब
Unsafe
स्पिफेन एमआर 50mg/4mg टैबलेट लेते समय शराब का सेवन न करें क्योंकि इससे उनींदापन बढ़ सकता है। इससे पेट से खून बहने का खतरा भी बढ़ सकता है।
गर्भावस्था
Unsafe
स्पिफेन एमआर 50mg/4mg टैबलेट को गर्भवती महिलाओं में उपयोग के लिए अनुशंसित नहीं किया जाता है। यदि आपको इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
स्तनपान
Caution
कृपया स्पिफेन एमआर 50mg/4mg टैबलेट लेने से पहले अपने चिकित्सक से परामर्श करें, आपका चिकित्सक केवल तभी दवा लिखेगा जब लाभ जोखिम से अधिक होंगे।
ड्राइविंग
Caution
स्पिफेन एमआर 50mg/4mg टैबलेट के कारण चक्कर आना, नींद आना और शरीर की हरकतें कम हो सकती हैं। जब तक आप सतर्क न हों, तब तक वाहन न चलाएं या मशीनरी न चलाएं।
जिगर
Caution
लीवर की खराबी वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की खराबी है या इससे संबंधित कोई चिंता है, तो कृपया अपने डॉक्टर से परामर्श करें।
किडनी
Caution
गुर्दे की खराबी वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की खराबी है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
Unsafe
स्पिफेन एमआर 50mg/4mg टैबलेट को बच्चों को नहीं दिया जाना चाहिए क्योंकि इसकी सुरक्षा और प्रभावशीलता स्थापित नहीं हुई है।
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