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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet together with budesonide may increase the risk of serious infections.
How to manage the interaction:
Co-administration of budesonide along with TFCT NIB Tablet can lead to an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Using TFCT NIB Tablet together with budesonide may increase the risk of serious infections.
How to manage the interaction:
Co-administration of budesonide along with TFCT NIB Tablet can lead to an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet together with fludrocortisone may increase the risk of serious infections.
How to manage the interaction:
Although taking Fludrocortisone and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Using TFCT NIB Tablet together with fludrocortisone may increase the risk of serious infections.
How to manage the interaction:
Although taking Fludrocortisone and TFCT NIB Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking TFCT NIB Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with TFCT NIB Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking TFCT NIB Tablet with Thiotepa may increase the risk of infection.
How to manage the interaction:
Co-administration of Thiotepa with TFCT NIB Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with TFCT NIB Tablet:
Co-administration of carboplatin with TFCT NIB Tablet can increase the risk of serous infections.
How to manage the interaction:
Although there is an interaction, carboplatin can be taken with TFCT NIB Tablet if prescribed by the doctor. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, breathing difficulty, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
Co-administration of carboplatin with TFCT NIB Tablet can increase the risk of serous infections.
How to manage the interaction:
Although there is an interaction, carboplatin can be taken with TFCT NIB Tablet if prescribed by the doctor. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, breathing difficulty, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
When TFCT NIB Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between TFCT NIB Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
When TFCT NIB Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between TFCT NIB Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking azacitidine with TFCT NIB Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azacitidine and TFCT NIB Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
Taking azacitidine with TFCT NIB Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azacitidine and TFCT NIB Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet with betamethasone may increase the risk of serious infections. It may also increase the risk of gastrointestinal bleeding.
How to manage the interaction:
Although there is an interaction between betamethasone and TFCT NIB Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Using TFCT NIB Tablet with betamethasone may increase the risk of serious infections. It may also increase the risk of gastrointestinal bleeding.
How to manage the interaction:
Although there is an interaction between betamethasone and TFCT NIB Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet together with methylprednisolone may increase the risk of serious infections.
How to manage the interaction:
Although taking Methylprednisolone and TFCT NIB Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
Using TFCT NIB Tablet together with methylprednisolone may increase the risk of serious infections.
How to manage the interaction:
Although taking Methylprednisolone and TFCT NIB Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or bleeding, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with TFCT NIB Tablet:
Taking Itraconazole with TFCT NIB Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between TFCT NIB Tablet and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
Taking Itraconazole with TFCT NIB Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between TFCT NIB Tablet and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
TofacitinibAbatacept
Severe
How does the drug interact with TFCT NIB Tablet:
Using TFCT NIB Tablet together with abatacept can increase the risk of serious infections.
How to manage the interaction:
Taking Abatacept with TFCT NIB Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Using TFCT NIB Tablet together with abatacept can increase the risk of serious infections.
How to manage the interaction:
Taking Abatacept with TFCT NIB Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, sore throat, muscle aches, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking TFCT NIB Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with TFCT NIB Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking TFCT NIB Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with TFCT NIB Tablet, as it can lead to an interaction.
Product Substitutes
शराब
सावधानी
यह ज्ञात नहीं है कि शराब TFCT NIB टैबलेट 10's के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान TFCT NIB टैबलेट 10's नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो TFCT NIB टैबलेट 10's के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
TFCT NIB टैबलेट 10's लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर TFCT NIB टैबलेट 10's आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए TFCT NIB टैबलेट 10's की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए TFCT NIB टैबलेट 10's की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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