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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tisol Eye/Ear Drops 5 ml contains ofloxacin, an antibiotic used to treat eye infections caused by bacteria such as conjunctivitis and corneal ulcers. This medicine stops the growth of bacteria by inhibiting the gyrase enzyme and thereby helps reduce bacterial eye infections. This medicine is not effective for treating viral infections. Sometimes, you may experience certain common side effects, such as eye discomfort, irritation, eye pain, and stinging sensation.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
The combination of Amiodarone and Tisol Eye/Ear Drops 5 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Tisol Eye/Ear Drops 5 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Using bepridil together with Tisol Eye/Ear Drops 5 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Using Mesoridazine together with Tisol Eye/Ear Drops 5 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Tisol Eye/Ear Drops 5 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Tisol Eye/Ear Drops 5 ml:
Coadministration of Tisol Eye/Ear Drops 5 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tisol Eye/Ear Drops 5 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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