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Xylistin 0.5MIU Injection is used to treat bacterial infections. It contains Colistimethate Sodium.  It effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, it destroys the bacteria and successfully treats the infection. Common side effects of Xylistin 0.5MIU Injection may include injection site reactions, renal damage, visual disturbances, GI disturbances, dizziness, nausea, vomiting and muscle weakness.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Xylistin 0.5MIU Injection is known to interact with selective skeletal muscle relaxants (e.g. cyclobenzaprine, metaxalone), antifungals (e.g. amphotericin B) and aminoglycosides (e.g. capreomycin, vancomycin)

Drug-Food Interactions: Xylistin 0.5MIU Injection is known to interact with alcohol and Grapefruit.

Drug-Disease Interactions: Xylistin 0.5MIU Injection is known to interact with disease conditions, including kidney problems, myasthenia gravis (a muscle disorder), and porphyria (a blood disorder).

ColistinBCG vaccine
Critical

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Coadministration of Xylistin 0.5MIU Injection 10 ml along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Xylistin 0.5MIU Injection 10 ml with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Coadministration of Atracurium with Xylistin 0.5MIU Injection 10 ml can increase the risk of Atracurium side effects.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Atracurium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, slurred speech, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Co-administration of Xylistin 0.5MIU Injection 10 ml with Gentamicin can increase the levels and risk of Xylistin 0.5MIU Injection 10 ml side effects.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Coadministration of Streptomycin with Xylistin 0.5MIU Injection 10 ml may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinCisatracurium
Severe
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Coadministration of Cisatracurium with Xylistin 0.5MIU Injection 10 ml may increase the risk of side effects of Cisatracurium.

How to manage the interaction:
Although there is a possible interaction of Cisatracurium with Xylistin 0.5MIU Injection 10 ml, it can be taken if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, Slurred speech, Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Combining Xylistin 0.5MIU Injection 10 ml with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Coadministration of Xylistin 0.5MIU Injection 10 ml with Amikacin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Amikacin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Using Vecuronium with Xylistin 0.5MIU Injection 10 ml can make Vecuronium more effective in therapy.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Vecuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Using Pancuronium with Xylistin 0.5MIU Injection 10 ml can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xylistin 0.5MIU Injection 10 ml:
Using Suxamethonium together with Xylistin 0.5MIU Injection 10 ml may increase the effects of Suxamethonium.

How to manage the interaction:
Although there is a possible interaction between Xylistin 0.5MIU Injection 10 ml and Suxamethonium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash Paresthesia (tingling or pricking sensation) Dizziness Slurred speech Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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