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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zoladex LA 10.8 mg Injection is indicated in the treatment of breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used to treat prostate cancer in men. It contains Goserelin, which acts on the brain's pituitary gland and decreases the production of certain sex hormones (testosterone in men and oestrogen in women) in the body. In some cases, Zoladex LA 10.8 mg Injection may cause hot flushes, sweating, decreased sex drive, and injection site reactions such as pain, redness, swelling, bleeding or bruising.

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Drug-Drug Interactions

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GoserelinAnagrelide
Critical
GoserelinHalofantrine
Critical

Drug-Drug Interactions

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GoserelinAnagrelide
Critical
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Anagrelide with Zoladex LA 10.8 mg Injection can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Anagrelide with Zoladex LA 10.8 mg Injection is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinHalofantrine
Critical
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Halofantrine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and halofantrine together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinAmiodarone
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Coadministration of Zoladex LA 10.8 mg Injection with amiodarone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Zoladex LA 10.8 mg Injection with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Arsenic trioxide with Zoladex LA 10.8 mg Injection can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking arsenic trioxide and Zoladex LA 10.8 mg Injection together is generally avoided as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinIvabradine
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Ivabradine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and ivabradine together can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinDofetilide
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Dofetilide can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and dofetilide together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinCabozantinib
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Cabozantinib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and Cabozantinib together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinIbutilide
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Ibutilide can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and ibutilide together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinQuinidine
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection with Quinidine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection with Quinidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinCrizotinib
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Crizotinib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and Crizotinib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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