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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zymmune 100 Capsule is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Side effects of Zymmune 100 Capsule
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.

Drug-Drug Interactions

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CiclosporinBaricitinib
Critical
CiclosporinCidofovir
Critical

Drug-Drug Interactions

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CiclosporinBaricitinib
Critical
How does the drug interact with Zymmune 100 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Zymmune 100 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Zymmune 100 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Zymmune 100 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinBosentan
Critical
How does the drug interact with Zymmune 100 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Zymmune 100 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSimvastatin
Critical
How does the drug interact with Zymmune 100 Capsule:
Combining Zymmune 100 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Zymmune 100 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinPitavastatin
Critical
How does the drug interact with Zymmune 100 Capsule:
Coadministration of pitavastatin with Zymmune 100 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Zymmune 100 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinClarithromycin
Severe
How does the drug interact with Zymmune 100 Capsule:
Co-administration of Clarithromycin with Zymmune 100 Capsule may increase the effects of Zymmune 100 Capsule.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Zymmune 100 Capsule if prescribed by the doctor. Consult the prescriber if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, tremors, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinLovastatin
Severe
How does the drug interact with Zymmune 100 Capsule:
Co-administration of lovastatin with Zymmune 100 Capsule may significantly increase the blood levels of lovastatin. This can raise the chance of side effects such as liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury.

How to manage the interaction:
Although taking lovastatin with cyclosporine together can possibly result in an interaction, they can be taken if your doctor has prescribed it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor.
CiclosporinSulfasalazine
Severe
How does the drug interact with Zymmune 100 Capsule:
Coadministration of sulfasalazine with Zymmune 100 Capsule may significantly increase the side effects on kidneys.

How to manage the interaction:
Although there is a possible interaction between sulfasalazine and Zymmune 100 Capsule, they can be taken together if your doctor has prescribed them. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without first talking to a doctor.
CiclosporinSulfamethizole
Severe
How does the drug interact with Zymmune 100 Capsule:
Coadministration of sulfamethizole with Zymmune 100 Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between sulfamethizole and Zymmune 100 Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinOrlistat
Severe
How does the drug interact with Zymmune 100 Capsule:
Coadministration of Zymmune 100 Capsule with Orlistat can reduce the levels and effects of Zymmune 100 Capsule.

How to manage the interaction:
Although there is a possible interaction between Orlistat and Zymmune 100 Capsule, you can take these medicines together when prescribed by your doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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