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  3. Jakavi 5 mg Tablet Substitute

Jakavi 5 mg Tablet Substitute

Medicine Composition:

RUXOLITINIB-5MG

All Substitutes & Brand Comparisons

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When Should You Consider Switching from Jakavi 5 mg Tablet ?

Patients may explore substitutes in the following scenarios:

  • High monthly cost of Jakavi 5 mg Tablet
  • Non-availability in local pharmacies
  • Generic recommendation by a doctor
  • Side effects or better tolerability with alternatives

What to Know Before Switching

Before you switch from Jakavi 5 mg Tablet to another medicine, here are some important points to keep in mind:

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Same salt, different brands:

Most substitutes contain the same active ingredient - RUXOLITINIB-5MG, but the fillers, coating, or manufacturing quality may vary slightly.

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Consult your doctor first:

Even if the salt is the same, your doctor can confirm if the substitute is right for your condition, dosage, and health history.

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Watch out for allergies or reactions:

Some people may react differently to certain brands due to inactive ingredients. If you notice any side effects, inform your doctor immediately.

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Price ≠ effectiveness:

A lower-priced substitute doesn't mean it's less effective. Many generic medicines work just as well as branded ones.

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Check the dosage form and strength:

Always match the substitute’s strength (e.g., 5mg, 10mg) and form (tablet, capsule, syrup) with what your doctor prescribed.

Uses

Jakavi 5 mg Tablet is used in the treatment of Myelofibrosis, polycythaemia vera (PV), and graft-versus-host disease (GVHD). The detailed uses of Jakavi 5 mg Tablet are as follows:

  • Treat myelofibrosis (MF): Jakavi 5 mg Tablet is used for intermediate or high-risk primary myelofibrosis, post-polycythemia vera MF, and post-essential thrombocythemia MF. It helps reduce spleen size and alleviate symptoms like fatigue and bone pain.
  • Manage polycythemia vera (PV): Jakavi 5 mg Tablet is used for patients who are intolerant to or have an inadequate response to hydroxyurea. It controls elevated red blood cell counts and reduces thrombotic risk.
  • Treat graft-versus-host disease (GVHD): Jakavi 5 mg Tablet is used in steroid-refractory acute and chronic GVHD in patients aged 12 years and older. It suppresses immune overactivity and reduces inflammation.

Medicinal Benefits

Jakavi 5 mg Tablet belongs to the group of medicines called kinase inhibitors indicated in the treatment of myelofibrosis and polycythaemia vera in adults. It is also used to treat graft-versus-host disease in adults and children above 12 years of age. Jakavi 5 mg Tablet contains Ruxolitinib, which works by blocking the action of Janus-associated kinase enzymes, reduces the size of the spleen in patients with myelofibrosis and relieves symptoms like fever, bone pain, night sweats, and weight loss. Jakavi 5 mg Tablet selectively blocks enzymes called Janus Associated Kinases (JAK1 and JAK2); this helps relieve the symptoms, reduce spleen size and the volume of red blood cells produced in patients with polycythaemia vera, thus potentially reducing the risk of serious blood or vascular complications. Jakavi 5 mg Tablet reduces signs and symptoms of the acute and chronic forms of graft-versus-host disease, leading to disease improvement and survival of the transplanted cells.

FAQs

The substitutes of Jakavi 5 mg Tablet contain the same active salt(s) - RUXOLITINIB-5MG. However, they may differ in price, manufacturing quality, and inactive ingredients. Speak to your doctor to find a suitable option.

Switching to a generic substitute medicine in the place of Jakavi 5 mg Tablet is often possible if it has the same salt, strength, and dosage form. But always check with your doctor before making any changes to your medication.

Generics versions of Jakavi 5 mg Tablet are typically more affordable because they don’t include the original brand's research, development, and marketing costs. They contain the same active ingredient and are approved for safety and effectiveness.

Most people don’t notice any difference. However, some may react to different fillers or coatings. If you notice any unusual symptoms after switching, consult your doctor.

Make sure the new medicine has the same active salt, strength, dosage form. Always confirm the change with your doctor or pharmacist.

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