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  3. 4PH 40 mg Tablet 10's

4PH 40 mg Tablet 10's, Pack of 10 TABLETS
4PH 40 mg Tablet 10's, Pack of 10 TABLETS
4PH 40 mg Tablet 10's, Pack of 10 TABLETS
4PH 40 mg Tablet 10's, Pack of 10 TABLETS
4PH 40 mg Tablet 10's, Pack of 10 TABLETS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

4PH 40 mg Tablet reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour). It helps in reducing the stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn. In some cases, it may cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About 4PH 40 mg Tablet

4PH 40 mg Tablet belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour).

4PH 40 mg Tablet helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. 4PH 40 mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take 4PH 40 mg Tablet 1-2 hours prior to food. You are advised to take 4PH 40 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, 4PH 40 mg Tablet might cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen. 

4PH 40 mg Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to 4PH 40 mg Tablet , or will have an endoscopy in the future. Prolonged intake of 4PH 40 mg Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium, and Vitamin D, leading to osteoporosis.

Uses of 4PH 40 mg Tablet

4PH 40 mg Tablet is used in the treatment of hyperacidity, heartburn, stomach ulcer and zollinger-ellison syndrome. The detailed uses of 4PH 40 mg Tablet are as follows:
• Management of Gastroesophageal Reflux Disease (GERD): 4PH 40 mg Tablet effectively reduces symptoms of GERD, such as heartburn and acid regurgitation, by lowering stomach acid production.
• Healing of Erosive Esophagitis: 4PH 40 mg Tablet is often prescribed to promote the healing of inflamed esophageal tissue caused by prolonged exposure to stomach acid.
• Treatment of Zollinger-Ellison Syndrome: 4PH 40 mg Tablet is used to manage Zollinger-Ellison syndrome, a condition that leads to excessive stomach acid production.
• Prevention of Peptic Ulcers: 4PH 40 mg Tablet helps prevent peptic ulcer formation, particularly in individuals undergoing long-term NSAID treatment.
• Eradication of Helicobacter pylori: 4PH 40 mg Tablet is sometimes included in combination therapy to eliminate Helicobacter pylori infections, which are associated with peptic ulcers.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take 4PH 40 mg Tablet in doses as prescribed by your doctor with the help of a measuring cup. Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

4PH 40 mg Tablet is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. 4PH 40 mg Tablet works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

How 4PH 40 mg Tablet Works

4PH 40 mg Tablet helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. 4PH 40 mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Storage

Store in a cool and dry place away from sunlight
Side effects of 4PH 40 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of 4PH 40 mg Tablet

Do not take more than the prescribed dose of 4PH 40 mg Tablet as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, sweating, nausea, fast heartbeat, dry mouth, headache or flushing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking 4PH 40 mg Tablet if you are allergic to 4PH 40 mg Tablet or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. 4PH 40 mg Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of 4PH 40 mg Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of 4PH 40 mg Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
EsomeprazoleCitalopram
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with 4PH 40 mg Tablet:
4PH 40 mg Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking 4PH 40 mg Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with 4PH 40 mg Tablet:
Combining 4PH 40 mg Tablet with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of 4PH 40 mg Tablet with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleGefitinib
Severe
How does the drug interact with 4PH 40 mg Tablet:
Taking gefitinib with 4PH 40 mg Tablet may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking 4PH 40 mg Tablet and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking 4PH 40 mg Tablet. Do not stop taking any medications without consulting a doctor.
EsomeprazoleAtazanavir
Severe
How does the drug interact with 4PH 40 mg Tablet:
4PH 40 mg Tablet reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between 4PH 40 mg Tablet and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with 4PH 40 mg Tablet:
4PH 40 mg Tablet may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking 4PH 40 mg Tablet with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with 4PH 40 mg Tablet:
Using Dasatinib together with 4PH 40 mg Tablet may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking 4PH 40 mg Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with 4PH 40 mg Tablet:
Coadministration of erlotinib and 4PH 40 mg Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and 4PH 40 mg Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with 4PH 40 mg Tablet:
Taking tacrolimus with 4PH 40 mg Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking 4PH 40 mg Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with 4PH 40 mg Tablet:
4PH 40 mg Tablet can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of 4PH 40 mg Tablet with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with 4PH 40 mg Tablet:
Coadministration of Clopidogrel with 4PH 40 mg Tablet may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and 4PH 40 mg Tablet together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

4PH 40 mg Tablet Substitute

Substitutes safety advice

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  • Nexpro Fast 40 Tablet 10's

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Product Substitutes

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Alcohol

Caution

Drinking alcohol with 4PH 40 mg Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of 4PH 40 mg Tablet .

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Pregnancy

Caution

4PH 40 mg Tablet isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake of 4PH 40 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

4PH 40 mg Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of 4PH 40 mg Tablet . Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

In some cases, 4PH 40 mg Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

4PH 40 mg Tablet should be taken with precaution in patients with liver disease.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking 4PH 40 mg Tablet .

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Children

Caution

4PH 40 mg Tablet should not be prescribed for children under 5 years of age. 4PH 40 mg Tablet is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

FAQs

4PH 40 mg Tablet is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.

4PH 40 mg Tablet is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

No. 4PH 40 mg Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes. 4PH 40 mg Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

There's no firm evidence to suggest that taking 4PH 40 mg Tablet will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

You can eat and drink normally while taking 4PH 40 mg Tablet . However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Prolonged intake of 4PH 40 mg Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

4PH 40 mg Tablet should be used in children only if prescribed by the doctor. Please consult the doctor before giving 4PH 40 mg Tablet to children.

4PH 40 mg Tablet should be taken an hour before meals.

4PH 40 mg Tablet is usually taken on an empty stomach, first thing in the morning. If you take 4PH 40 mg Tablet twice a day, take 1 dose in the morning and 1 dose in the evening.

Yes, 4PH 40 mg Tablet can be taken with domperidone if prescribed by the doctor.

Antacids can be taken along with 4PH 40 mg Tablet if prescribed by the doctor. However, it is advised to maintain a gap of 2 hours between 4PH 40 mg Tablet and antacid medicines.

It is advised to take 4PH 40 mg Tablet for the duration prescribed by the doctor. 4PH 40 mg Tablet is usually prescribed for a short term. However, it may be indicated for a long term use in cases like Zollinger-Ellison syndrome and ulcer disease.

Do not discontinue 4PH 40 mg Tablet without consulting your doctor. To treat your condition effectively, take 4PH 40 mg Tablet for the duration prescribed by the physician.

4PH 40 mg Tablet may cause weight gain in rare cases. Maintain a proper weight by eating healthy food and exercising regularly.

Yes, 4PH 40 mg Tablet is safe to use if prescribed by the doctor.

4PH 40 mg Tablet can be taken with ranitidine if prescribed by the doctor. No interactions were found between both the medicines.

Drinking alcohol with 4PH 40 mg Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So, try to avoid/limit alcohol consumption with 4PH 40 mg Tablet .

If you miss a dose of 4PH 40 mg Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

4PH 40 mg Tablet might cause side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen.

Consult the doctor before taking other medicines while using 4PH 40 mg Tablet to prevent interactions. Let the doctor know if you are taking blood thinners, antifungal agents, anti-HIV drugs, anti-viral drugs, iron supplements, antibiotics, cardiac medicines and anti-cancer drugs.

Country of origin

India

Manufacturer/Marketer address

A/201-202, Dipti Classic, 32/34 Surendra Road, Andheri (E), Mumbai Maharashtra 400093 India
Other Info - 4PH0002

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Author Details

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Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 21, 2025 | 2:28 PM IST

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Reference

  1. https://www.drugs.com/mtm/esomeprazole.html
  2. https://www.nhs.uk/medicines/esomeprazole/
  3. https://www.medicines.org.uk/emc/files/pil.3002.pdf
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