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  3. Abamune-L Tablet 30's

Abamune-L Tablet 30's, Pack of 1 TABLET
Abamune-L Tablet 30's, Pack of 1 TABLET
Abamune-L Tablet 30's, Pack of 1 TABLET
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Abamune-L Tablet is used to treat HIV infection. It contains Abacavir and Lamivudine which work by interfering with the working of certain enzymes necessary for virus reproduction. In some cases, this medicine may cause side effects such as headache, tiredness, dizziness, nausea, diarrhoea, rash, and fever. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ABACAVIR-600MG + LAMIVUDINE-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Abamune-L Tablet

Abamune-L Tablet belongs to a class of drugs called antiretrovirals used to treat HIV infection. Abamune-L Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Abamune-L Tablet is a combination of two drugs: Abacavir and Lamivudine. Both Abacavir and Lamivudine are nucleoside reverse transcriptase inhibitors. Abamune-L Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Abamune-L Tablet helps in treating HIV infection.

Take Abamune-L Tablet as prescribed by your doctor. You are advised to take Abamune-L Tablet for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience headaches, tiredness, dizziness, nausea, diarrhoea, rash, and fever. Most of these side effects of Abamune-L Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any components present in Abamune-L Tablet or other medicines or foods (e.g. soya or peanut). If you are pregnant or planning for pregnancy, please consult a doctor before taking Abamune-L Tablet . Avoid breastfeeding while taking Abamune-L Tablet as it may pass into breast milk. Abamune-L Tablet is not recommended for children below 18 years of age. You are advised to avoid alcohol consumption with Abamune-L Tablet as it may increase the risk of liver damage. Drive only if you are alert, as Abamune-L Tablet may cause dizziness.

Uses of Abamune-L Tablet

Treatment of HIV infection

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Directions for Use

• Abamune-L Tablet can be taken with or without food as prescribed by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Abamune-L Tablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Abamune-L Tablet is a combination of two drugs, Abacavir and Lamivudine, used to treat HIV infection. Both Abacavir and Lamivudine are nucleoside reverse transcriptase inhibitors. Abamune-L Tablet interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Thus, Abamune-L Tablet helps in treating HIV infection. Taking Abamune-L Tablet along with practising safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

How Abamune-L Tablet Works

Abamune-L Tablet is a combination of two drugs: Abacavir and Lamivudine. Both Abacavir and Lamivudine are nucleoside reverse transcriptase inhibitors. Abamune-L Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Abamune-L Tablet helps in treating HIV infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Abamune-L Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Abamune-L Tablet
  • Stop the medication if a healthcare professional confirms or suspects an allergy.
  • If an allergy to the specific drug is confirmed, your doctor will usually suggest an alternative medication.
  • Your doctor might recommend antihistamine medications (such as diphenhydramine) to help block the chemicals in the body that cause allergic reactions and corticosteroids for more serious reactions.
  • In cases where the allergy is not certain, doctors might administer gradually increasing amounts of the suspected drug (graded challenges) or slowly increase the dose over time to help the person safely build tolerance (drug desensitization), all under careful medical supervision.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

What if I have taken an overdose of Abamune-L Tablet

Take Abamune-L Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you are allergic to Abamune-L Tablet or other medicines, soya or peanut. If you are pregnant or planning for pregnancy, please consult a doctor before taking Abamune-L Tablet . Avoid breastfeeding while taking Abamune-L Tablet as it may pass into breast milk. Abamune-L Tablet is not recommended for children below 18 years of age. You are advised to take proper precautions if you are infected with HIV to prevent infection from spreading to others through sexual contact or body fluids. If you experience stomach pain, vomiting or nausea while taking Abamune-L Tablet , please consult a doctor immediately as these might be symptoms of a rare but severe side effect known as lactic acidosis (excess of lactic acid in the blood). You are recommended to avoid alcohol consumption with Abamune-L Tablet as it may increase the risk of liver damage. Drive only if you are alert, as Abamune-L Tablet may cause dizziness.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
LamivudineZalcitabine
Severe

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Abamune-L Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Abamune-L Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
LamivudineZalcitabine
Severe
How does the drug interact with Abamune-L Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Abamune-L Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Abamune-L Tablet:
Combining Abamune-L Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Abamune-L Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineBexarotene
Severe
How does the drug interact with Abamune-L Tablet:
Taking bexarotene together with Abamune-L Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Abamune-L Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Abamune-L Tablet:
Abamune-L Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Abamune-L Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
LamivudineLomitapide
Severe
How does the drug interact with Abamune-L Tablet:
Taking Abamune-L Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Abamune-L Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
LamivudineTeriflunomide
Severe
How does the drug interact with Abamune-L Tablet:
Teriflunomide can cause Abamune-L Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Abamune-L Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineMipomersen
Severe
How does the drug interact with Abamune-L Tablet:
Taking Abamune-L Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Abamune-L Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
AbacavirLeflunomide
Severe
How does the drug interact with Abamune-L Tablet:
Leflunomide can cause liver problems, and combining it with Abamune-L Tablet, may increase the risk.

How to manage the interaction:
Co-administration of Abamune-L Tablet with Leflunomide can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, joint pain, rash, or stomach problems, contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis, as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Abamune-L Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid alcohol consumption with Abamune-L Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Abamune-L Tablet is given to pregnant women if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Abamune-L Tablet as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Abamune-L Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Abamune-L Tablet .

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Liver

Caution

Take Abamune-L Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Abamune-L Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Abamune-L Tablet is not recommended for children below 18 years of age.

FAQs

Abamune-L Tablet contains Abacavir and Lamivudine. Abamune-L Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Abamune-L Tablet helps in treating HIV infection.

HIV infection may still be transmitted to other persons while using Abamune-L Tablet . Abamune-L Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to avoid transmission of HIV while taking Abamune-L Tablet .

Abamune-L Tablet does not cure HIV infection. Abamune-L Tablet reduces the amount of HIV in the body and improves the immune system's functioning.

Abamune-L Tablet may increase the risk of treatment failure. So Abamune-L Tablet should not be stopped without consulting your doctor.

Do not stop taking Abamune-L Tablet without consulting your doctor. Stopping Abamune-L Tablet before treatment may worsen your hepatitis. This can occur during the first few months after you stop taking Abamune-L Tablet . Take the Abamune-L Tablet strictly as instructed, and do not miss any dose.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ABA0012

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:28 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021652s022lbl.pdf
  2. https://www.drugs.com/drug-interactions/abacavir-lamivudine-index.html?filter=3

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