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Acalnib 100 mg Capsule 30's is used to treat Mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL). It contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.
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About Acalnib 100 mg Capsule 30's
Acalnib 100 mg Capsule 30's is a tyrosine kinase inhibitor or cancer growth inhibitor that is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy (cancer), as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Cancer is caused by a genetic mutation that causes our cells to divide uncontrollably and spread into neighbouring tissues.
Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.
To treat your condition effectually, continue using Acalnib 100 mg Capsule 30's for as long as your doctor has prescribed it. The most common adverse reactions are anaemia (lack of blood), neutropenia (low count of neutrophils), upper respiratory tract infection, thrombocytopenia (Low platelet level), headache, diarrhoea, and musculoskeletal pain. You should talk to your doctor if you persistently experience these side effects.
It is recommended not to use if you are hypersensitive to any component present in Acalnib 100 mg Capsule 30's and suffer from Severe Hepatic Impairment. Acalnib 100 mg Capsule 30's can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Acalnib 100 mg Capsule 30's. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.
Uses of Acalnib 100 mg Capsule 30's
Directions for Use
Medicinal Benefits
Acalnib 100 mg Capsule 30's is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy, as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that send signals to cells, directing them to grow and divide. Acalabrutinib blocks these signals to cancer cells. Cancer cells die when their signals are interrupted. This could help to delay the progression of the cancer.
How Acalnib 100 mg Capsule 30's Works
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What if I have taken an overdose of Acalnib 100 mg Capsule 30's
Drug Warnings
Before taking the Acalnib 100 mg Capsule 30's, inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Acalabrutinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Acalabrutinib and for at least one week after the last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements.
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Alcohol
Unsafe
Avoid alcohol consumption while on treatment with Acalnib 100 mg Capsule 30's.
Pregnancy
Unsafe
Acalnib 100 mg Capsule 30's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.
Breast Feeding
Unsafe
Acalnib 100 mg Capsule 30's should not be used in breastfeeding. Discuss with your doctor if you have any concerns.
Driving
Caution
Acalnib 100 mg Capsule 30's does not influence the ability to drive or use machines. However, go only if you are alert, as the Acalnib 100 mg Capsule 30's may cause tiredness in some people.
Liver
Caution
Avoid using Acalnib 100 mg Capsule 30's in patients with severe hepatic impairment. The safety of Acalnib 100 mg Capsule 30's has not been evaluated in patients with moderate or severe hepatic impairment. So, caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with liver impairment. If you have a pre-existing or a history of liver disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.
Kidney
Caution
Caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with kidney impairment. If you have a pre-existing or a history of kidney disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.
Children
Caution
Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.
Acalnib 100 mg Capsule 30's is used to treat Mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL).
Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that send signals to cells, directing them to grow and divide. Acalabrutinib blocks these signals to cancer cells. Cancer cells die when their signals are interrupted. This could help to delay the progression of the cancer.
While taking Acalnib 100 mg Capsule 30's, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Acalnib 100 mg Capsule 30's.
Mantle cell lymphoma (MCL) is diagnosed by taking a biopsy of tumour tissue and examining the cells under a microscope.
You can take the missed dose if you forget to take your acalabrutinib, which is less than 3 hours after your usual time. Then, take the next dose at the regular time. Do not take your missed dose if more than 3 hours have passed. Wait and take the next dose at the regular time. Do not take a double dose to make up for a missing one.
Acalnib 100 mg Capsule 30's may cause nausea as a side effect. If you experience nausea, you can manage it by drinking plenty of clear liquids like water, fruit juices, or flat soda to prevent dehydration. Eat smaller, more frequent meals of bland foods that are easy to digest, like crackers, toast, or bananas. Avoid greasy, fried, sweet, or spicy foods. However, consult your doctor if nausea persists or worsens.
To relieve diarrhoea caused by Acalnib 100 mg Capsule 30's, stay hydrated by drinking plenty of water and clear fluids. Follow a bland diet of bananas, rice, applesauce, and toast. Avoid spicy, fatty, or high-fiber foods that can make diarrhoea worse. Talk to the doctor if you experience severe diarrhoea.
Avoid eating grapefruit and drinking grapefruit juice while taking Acalnib 100 mg Capsule 30's, as it may interact with the medication. Limit intake of alcohol as it may increase the risk of bleeding.
Consult the doctor if you notice changes in your skin like rash, light bruising, and small red or purple spots on your skin after taking Acalnib 100 mg Capsule 30's.
Acalnib 100 mg Capsule 30's may cause bleeding gums due to reduced platelets. Try gentle brushing with a soft-bristled toothbrush. If the issue persists, consult your doctor for appropriate treatment.
After starting treatment with Acalnib 100 mg Capsule 30's, you may feel tired or weak. To cope with this, prioritize rest and pace yourself. Take breaks, nap if needed, and engage in gentle exercises like yoga or short walks. Stay hydrated, eat small, frequent meals, and avoid heavy lifting or strenuous activities.
The doctor may advise regular blood tests before and during the treatment with Acalnib 100 mg Capsule 30's to check blood count. Additionally, liver and kidney function tests may also be recommended by the doctor.
The common side effects of Acalnib 100 mg Capsule 30's include anaemia (lack of blood), neutropenia (low count of neutrophils), upper respiratory tract infection, thrombocytopenia (Low platelet level), headache, diarrhoea, and musculoskeletal pain. You should talk to your doctor if you persistently experience these side effects.
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