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  3. Accentrix Livi 0.5 mg Injection 1's

Accentrix Livi 0.5 mg Injection 1's, Pack of 1 INJECTION
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Composition :

RANIBIZUMAB-0.5MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Accentrix Livi 0.5 mg Injection

Accentrix Livi 0.5 mg Injection belongs to the group of medicines called anti-neovascularisation agents used to treat eye diseases causing vision impairment, such as neovascular (wet) age-related macular degeneration, macular oedema following retinal vein occlusion, diabetic macular oedema, proliferative diabetic retinopathy, and choroidal neovascularization. It is also used to treat retinopathy of prematurity in babies born prematurely.

Accentrix Livi 0.5 mg Injection contains Ranibizumab, a vascular endothelial growth factor A (VEGF-A) antagonist. It binds to VEGF-A (a protein that causes abnormal blood vessel growth and swelling, leading to vision impairment) present in the eyes, blocks its action, and prevents abnormal growth and swelling. It helps stabilise and improve vision.

In some cases, Accentrix Livi 0.5 mg Injection may cause side effects such as eye pain, inflammation, retinal bleeding, dry eye, eye irritation, and redness or itching of the eye. Most of these side effects may not require medical attention and resolve over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any components in Accentrix Livi 0.5 mg Injection. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy. Accentrix Livi 0.5 mg Injection is not recommended during breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Accentrix Livi 0.5 mg Injection

Accentrix Livi 0.5 mg Injection is used in the treatment of Neovascular (wet) age-related macular degeneration (AMD), macular oedema following retinal vein occlusion (RVO), diabetic macular oedema (DME), proliferative diabetic retinopathy (PDR), and choroidal neovascularization (CNV). Also used in premature babies to treat retinopathy of prematurity (ROP). The detailed uses of Accentrix Livi 0.5 mg Injection are as follows:<br/>• Treat wet age-related macular degeneration (AMD): Accentrix Livi 0.5 mg Injection inhibits abnormal blood vessel growth under the retina, helping preserve central vision and slow disease progression.<br/>• Manage diabetic macular edema (DME): Accentrix Livi 0.5 mg Injection reduces retinal swelling caused by fluid leakage in diabetic patients, improving visual acuity.<br/>• Treat macular edema due to retinal vein occlusion (RVO): Accentrix Livi 0.5 mg Injection helps restore vision by reducing fluid buildup in the retina following vein blockage.<br/>• Support therapy for diabetic retinopathy: Accentrix Livi 0.5 mg Injection improves retinal health and prevents further damage in patients with advanced diabetic eye disease.<br/>• Treat myopic choroidal neovascularization (mCNV): Accentrix Livi 0.5 mg Injection is used to manage vision loss in patients with severe nearsightedness due to abnormal blood vessel growth.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication, to improve effectiveness.• Accentrix Livi 0.5 mg Injection will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Accentrix Livi 0.5 mg Injection belongs to the group of medicines called anti-neovascularisation agents used to treat eye diseases causing vision impairment, such as neovascular (wet) age-related macular degeneration (AMD), macular oedema following retinal vein occlusion (RVO), diabetic macular oedema (DME), proliferative diabetic retinopathy (PDR), and choroidal neovascularization (CNV). Accentrix Livi 0.5 mg Injection contains Ranibizumab, a vascular endothelial growth factor A (VEGF-A) antagonist, which binds to VEGF-A (a protein which causes abnormal blood vessel growth and swelling, leading to vision impairment) present in the eyes, blocks its action and prevents abnormal growth and swelling. It helps stabilise and improve your vision. This medicine may also be indicated in preterm infants for the treatment of retinopathy of prematurity (ROP).

How Accentrix Livi 0.5 mg Injection Works

Accentrix Livi 0.5 mg Injection contains Ranibizumab, a vascular endothelial growth factor A (VEGF-A) antagonist. It binds to VEGF-A (a protein that causes abnormal blood vessel growth and swelling, leading to vision impairment) present in the eyes, blocks its action, and prevents abnormal growth and swelling. It helps stabilise and improve vision.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Accentrix Livi 0.5 mg Injection

As Accentrix Livi 0.5 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Accentrix Livi 0.5 mg Injection if you are allergic to any of its components, if you have an infection in or around the eye, severe intraocular inflammation (pain or redness in the eye) or if you are breastfeeding. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy. Seek immediate medical attention if you experience worsening eye redness, eye pain or increased discomfort, an increased number of small particles in your vision, blurred or decreased vision, or increased sensitivity to light. Inform the doctor if you have a history of eye conditions, eye treatments, or stroke. Let the doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, whole grains, and fruits in your diet.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

OPHTHALMOLOGIC AGENTS

Accentrix Livi 0.5 mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Accentrix Livi 0.5 mg Injection. Please consult the doctor.

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Pregnancy

Caution

Accentrix Livi 0.5 mg Injection should not be used during pregnancy unless the benefits outweigh the risks. Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

It is not known whether Accentrix Livi 0.5 mg Injection passes into breast milk. However, if you are breastfeeding, inform your doctor before receiving Accentrix Livi 0.5 mg Injection.

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Driving

Caution

Accentrix Livi 0.5 mg Injection may cause temporary vision blurring. Avoid driving or operating heavy machinery if you experience this.

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Liver

Caution

If you have a history of liver problems, inform the doctor before receiving Accentrix Livi 0.5 mg Injection.

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Kidney

Caution

Dose adjustment may not be needed in patients with renal impairment. However, if you have a history of kidney problems, inform the doctor before receiving Accentrix Livi 0.5 mg Injection.

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Children

Caution

Accentrix Livi 0.5 mg Injection is not recommended for children as the safety and effectiveness have not been established except for retinopathy of prematurity (ROP) in babies born prematurely. However, the safety profile in preterm infants has not been established beyond 2 years.

Have a query?

FAQs

Accentrix Livi 0.5 mg Injection is used to treat Neovascular (wet) age-related macular degeneration (AMD), macular oedema following retinal vein occlusion (RVO), diabetic macular oedema (DME), proliferative diabetic retinopathy (PDR), and choroidal neovascularization (CNV). Also used in premature babies to treat retinopathy of prematurity (ROP).

Accentrix Livi 0.5 mg Injection works by stopping abnormal blood vessel growth and leakage in the eyes that may cause vision loss.

Accentrix Livi 0.5 mg Injection may affect fertility. Fertility problems may interfere with the ability to get pregnant or father a child. Consult the doctor if you have any concerns.

Accentrix Livi 0.5 mg Injection can be used in the elderly aged 65 years or older if prescribed by the doctor. However, talk to the doctor if you have any concerns.

Accentrix Livi 0.5 mg Injection should not be used by individuals who are allergic to any of its active ingredients and those who have an eye infection, eye inflammation, or severe inflammation within the eye. Always consult your healthcare provider before using this medication.

The duration of treatment with Accentrix Livi 0.5 mg Injection depends on the condition being treated and your response to the medication. Your healthcare provider will determine the appropriate length of treatment.

After taking Accentrix Livi 0.5 mg Injection, inform your doctor if you experience eye pain, discomfort, redness, blurred vision, or increased sensitivity to light. Monitor for signs of infection or retinal detachment, and contact your doctor if these occur. Your doctor may also check eye pressure, as it can temporarily rise. Additionally, inform your doctor if you have a history of eye conditions or stroke-related symptoms.

Accentrix Livi 0.5 mg Injection causes side effects such as inflammation of eye, retinal bleeding (bleeding in the back of eye), eye pain, a bloodshot eye, small particles or spots in the vision, eye irritation, dry eye, redness or itching in eye, and increased eye pressure. However, please contact a doctor if these side effects persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - ACC0150

Disclaimer

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:06 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.307.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125156s105lbl.pdf
  3. https://www.novartis.com/sg-en/sites/novartis_sg/files/Lucentis-Feb2022.SIN-app180522-pdf.pdf
  4. https://medlineplus.gov/druginfo/meds/a607044.html
  5. https://www.drugs.com/cdi/ranibizumab.html

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