Ace-Coxib-90 Tablet 1 is used to treat pain, swelling and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout in people greater than 16 years of age. Besides this, it is also used to treat moderate pain after dental surgery. Osteoarthritis is a degenerative bone disease in which the tissue supporting the joints wears down. Rheumatoid arthritis is a condition in which the immune system attacks its tissue, leading to joint pain and inflammation. Ankylosing spondylitis is the inflammation of the spine and large joints. Gout is characterized by pain and inflammation in the joints due to the deposition of uric acid crystals.

Ace-Coxib-90 Tablet 1 contains ‘etoricoxib’, which works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, which is responsible for pain, swelling and inflammation. Ace-Coxib-90 Tablet 1 acts at the affected area and acts specifically at the pain site. The benefit of COX-2 inhibitors is that they protect the stomach lining from the ulcer effect caused by other painkillers, ibuprofen and aspirin.

Ace-Coxib-90 Tablet 1 is available in tablet form and injection. Take an oral form of Ace-Coxib-90 Tablet 1 as advised by your doctor. A healthcare professional will give the injection form of Ace-Coxib-90 Tablet 1, do not self-administer. Common side-effects of Ace-Coxib-90 Tablet 1 are stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, gastritis (inflammation of the lining of the stomach), heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, inflammation of the oesophagus (food pipe), mouth ulcers, general weakness and flu-like illness (fever, cold, cough, or sore throat).

Do not take Ace-Coxib-90 Tablet 1 if you are allergic to etoricoxib, other pain killers or other ingredients. Inform your doctor if you have ulcers or bleeding in your stomach, severe liver and/or kidney impairment, colitis (inflammation of the large intestine), uncontrolled blood pressure, or heart problems such as chest pain, heart attack, heart failure and stroke. Do not take it if you are under 16 years of age, pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you are dehydrated (because of vomiting or diarrhoea), have oedema (swelling due to fluid retention), have an infection, diabetes (high blood sugar) and high cholesterol, are a smoker or have an age above 65 years.

Swallow it as a whole with water; do not crush, break or chew it.

Ace-Coxib-90 Tablet 1 contains ‘etoricoxib’ which is a non-steroidal anti-inflammatory drug (NSAID). It acts as both analgesic (reduces pain) and an anti-inflammatory (reduces inflammation) agent. It is a selective COX-2 inhibitor. COX-2 enzymes are responsible for converting arachidonic acid to prostaglandins which are inflammatory mediators. The blocking of COX-2 reduces the production of prostaglandins, eventually decreasing pain and inflammation.

Before taking Ace-Coxib-90 Tablet 1, inform your doctor if you have a history of stomach bleeding or ulcer, liver or kidney diseases, dehydration because of prolonged vomiting or diarrhoea and swelling due to fluid retention. Inform your doctor if you have high blood pressure that is not treated or controlled, as Ace-Coxib-90 Tablet 1 may increase blood pressure in some cases. Do not take Ace-Coxib-90 Tablet 1 if you are treated for infection, as Ace-Coxib-90 Tablet 1 can mask fever (a sign of disease). Do not take Ace-Coxib-90 Tablet 1 if you smoke, have diabetes (high blood sugar), or high cholesterol, as Ace-Coxib-90 Tablet 1 increases the risk of heart attack or stroke. Avoid lying down for at least half an hour after using Ace-Coxib-90 Tablet 1. People who have had heart attacks and strokes should not take Ace-Coxib-90 Tablet 1.