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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Aciloc 300 Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. It is also used to prevent and treat stomach ulcers. It contains Ranitidine, which helps reduce stomach acid. It may cause common side effects like headache, diarrhoea, constipation, and shortness of breath. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

RANITIDINE-300MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Aciloc 300 Tablet

Aciloc 300 Tablet is used to treat indigestion, heartburn and acid reflux. Aciloc 300 Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Aciloc 300 Tablet is also used to prevent and treat stomach ulcers. Often, Aciloc 300 Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Aciloc 300 Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall. It is responsible for the release of gastric acid secretion - extra gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Take this medication exactly as prescribed by your doctor. It would help if you kept taking medicine for as long as your doctor recommends. If you stop early, your symptoms may come back, and your condition may worsen. Aciloc 300 Tablet might have common side effects like headache, diarrhoea, constipation, and shortness of breath. These side effects are temporary and may be resolved after some time. However, if these side effects persist, contact your doctor.

It is recommended not to take Aciloc 300 Tablet if you are allergic to any components present in Aciloc 300 Tablet . If you are pregnant, planning to become pregnant, or are breastfeeding, you should not take this medication unless your doctor says it is necessary. Inform your doctor if you have stomach or intestinal cancer, liver problems, or will have an endoscopy in the future. Also, let your doctor know about your health condition and all the medicines you are taking before taking Aciloc 300 Tablet to rule out any side effects.

Uses of Aciloc 300 Tablet

Aciloc 300 Tablet used in the treatment of Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, and Peptic Ulcer. The detailed uses of Aciloc 300 Tablet are as follows:
• Treatment of Heartburn: Aciloc 300 Tablet used to treat heartburn and acid reflux by reducing excess stomach acid, providing relief from discomfort.
• Management of Peptic Ulcers: Aciloc 300 Tablet is involved in managing peptic ulcers by reducing stomach acid production and allowing ulcers to heal.
• Gastroesophageal Reflux Disease (GERD): Aciloc 300 Tablet helps to manage GERD by reducing severe acid reflux symptoms and preventing esophageal damage.
• Prevention of Gastric Acid-related Issues: Aciloc 300 Tablet can prevent gastric acid-related issues before surgeries or procedures, reducing the risk of complications.
• Support in Treating Zollinger-Ellison Syndrome: Aciloc 300 Tablet manages Zollinger-Ellison syndrome by decreasing excessive stomach acid production.

Directions for Use

Aciloc 300 Tablet should be swallowed as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Aciloc 300 Tablet helps in reducing the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger-Ellison Syndrome, in which the stomach makes an exceptionally high amount of acid.

How Aciloc 300 Tablet Works

Aciloc 300 Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall. It is responsible for the release of gastric acid secretion - excessive gastric acid secretion damages the tissues in the food pipe, stomach, and duodenum.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aciloc 300 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Aciloc 300 Tablet

Do not take more than the prescribed dose of Aciloc 300 Tablet as it may cause an overdose. The symptoms of overdose include lack of coordination, fainting or lightheadedness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Aciloc 300 Tablet if you are allergic to Aciloc 300 Tablet or H2 receptor blockers, have gastric cancer, or have liver disease. If you are a pregnant woman or nursing mother, do not consume Aciloc 300 Tablet without first consulting your doctor. Aciloc 300 Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), or anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines. Intake of Aciloc 300 Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous), immediately consult the doctor.

Drug-Drug Interactions

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RanitidineAtazanavir
Severe
RanitidineRilpivirine
Severe

Drug-Drug Interactions

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RanitidineAtazanavir
Severe
How does the drug interact with Aciloc 300 Tablet:
Taking atazanavir with Aciloc 300 Tablet can reduce the effectiveness of atazanavir.

How to manage the interaction:
Although taking Aciloc 300 Tablet together with Atazanavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineRilpivirine
Severe
How does the drug interact with Aciloc 300 Tablet:
Coadministration of Rilpivirine with Aciloc 300 Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of Rilpivirine.

How to manage the interaction:
Although taking Aciloc 300 Tablet together with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. To reduce the chance of interaction, take Aciloc 300 Tablet at least 12 hours before or 4 hours after taking rilpivirine. Do not discontinue any medicine without consulting a doctor.
RanitidineGefitinib
Severe
How does the drug interact with Aciloc 300 Tablet:
Coadministration of Gefitinib with Aciloc 300 Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of gefitinib

How to manage the interaction:
Taking Gefitinib with Aciloc 300 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that gefitinib is either taken 6 hours before or 6 hours after Aciloc 300 Tablet to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
RanitidineMesalazine
Severe
How does the drug interact with Aciloc 300 Tablet:
Co-administration of Aciloc 300 Tablet with Mesalazine can decrease the levels of Mesalazine, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalazine with Aciloc 300 Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
RanitidinePazopanib
Severe
How does the drug interact with Aciloc 300 Tablet:
Using Pazopanib with Aciloc 300 Tablet can reduce the effectiveness of pazopanib

How to manage the interaction:
Although taking Aciloc 300 Tablet together with Pazopanib can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RanitidineLoperamide
Severe
How does the drug interact with Aciloc 300 Tablet:
Coadministration of loperamide with Aciloc 300 Tablet may significantly increase the blood levels of loperamide. This can increase the risk of serious side effect like irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Aciloc 300 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
RanitidineDasatinib
Severe
How does the drug interact with Aciloc 300 Tablet:
Taking Aciloc 300 Tablet and Dasatinib together reduces the effectiveness of Dasatinib.

How to manage the interaction:
Although taking Aciloc 300 Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience any unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineCefuroxime
Moderate
How does the drug interact with Aciloc 300 Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
vv
RanitidineCefditoren
Moderate
How does the drug interact with Aciloc 300 Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
v

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid acid or heartburn triggering foods or drinks, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, raise your bedhead so your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backflowing through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid from flowing back into the food pipe.
  • Include high fibre-containing foods like berries, cherries, leafy green veggies (kale, spinach), and black peppers.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pylori infections.
  • Avoid continuous sitting, as it can increase stomach acid production. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Aciloc 300 Tablet Substitute

Substitutes safety advice
  • Rantac 300 Tablet 30's

    by Others

    2.84per tablet
  • Rantac OD 300 Tablet 10's

    by Others

    7.11per tablet
  • Ranitin-300 Tablet 20's

    by AYUR

    2.25per tablet
  • Histac 300 Tablet 20's

    by Others

    1.89per tablet
  • Rand 300 mg Tablet 10's

    by Others

    2.61per tablet
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Alcohol

Caution

Drinking alcohol with Aciloc 300 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So try to avoid consuming alcohol.

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Pregnancy

Safe if prescribed

Aciloc 300 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Aciloc 300 Tablet should be used in nursing women only if clinically needed, and the benefits outweigh the risks.

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Driving

Caution

Aciloc 300 Tablet has no or negligible influence on the ability to drive and use machines. In some cases, Aciloc 300 Tablet may cause dizziness and sleep. If you observe these symptoms, do not drive or operate machinery until you feel better.

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Liver

Caution

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Caution

If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Safe if prescribed

The dose needs to be adjusted based on your child’s weight.

FAQs

Aciloc 300 Tablet is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Aciloc 300 Tablet is also used to prevent and treat stomach ulcers. Often Aciloc 300 Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Ranitidine belongs to a class of drugs known as H2 receptor antagonists (gastrointestinal agents). Aciloc 300 Tablet works by lessening the quantity of acid produced in your stomach.

You can take Aciloc 300 Tablet with or without food. However, if you get symptoms whenever you eat or drink, take your medicine 30 minutes before having a drink, snack, or meal.

Aciloc 300 Tablet starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.

Aciloc 300 Tablet may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, and difficulty in breathing. Inform your doctor in case you notice any of these side effects.

No, Aciloc 300 Tablet prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.

The duration of the Aciloc 300 Tablet treatment depends on your specific condition and the doctor's recommendation.

Aciloc 300 Tablet is a common treatment for gastritis. However, if you have gastritis, it's essential to consult with a healthcare professional before using Aciloc 300 Tablet , especially for the long term. They can provide an accurate diagnosis and recommend appropriate alternative therapies.

Aciloc 300 Tablet typically starts working within 30 minutes to 1 hour. However, achieving complete symptom relief may take several days of consistent use.

No, the Aciloc 300 Tablet is not used for loose motion.

Aciloc 300 Tablet typically starts working within 30 minutes. Individual responses may vary from person to person.

Aciloc 300 Tablet is a widely used over-the-counter antacid medication and is generally very well tolerated.

Yes, it can be used in children; the dose must be adjusted based on your child's weight. If your child is experiencing heartburn, acid reflux, or other digestive issues, it's important to consult with a paediatrician. They can provide an accurate diagnosis and recommend appropriate alternative treatments that are safe and effective for children.

Yes, Aciloc 300 Tablet can cause constipation in some people. While constipation is not a common side effect of Ranitidine, it can occur in some individuals.

Aciloc 300 Tablet contains Ranitidine (a histamine-2 (H2) receptor blocker), whereas PAN 40 contains Pantoprazole (proton-pump inhibitors). Both are used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.

Do not take Aciloc 300 Tablet for longer than two weeks unless your doctor tells you to. Long-term use of Ranitidine may increase the risk of side effects. If you're taking Ranitidine, discussing this with your doctor and exploring alternative options is essential.

Take Aciloc 300 Tablet with or without food as directed by your doctor.

Yes, Ranitidine was once considered an effective medication for treating conditions like heartburn, acid reflux, and ulcers. It works by reducing the amount of acid produced by the stomach.

To ensure safe medication use, always follow your doctor's instructions, read medication labels carefully, take medications at the right time, inform your doctor about allergies or medical conditions, report any side effects, store medications properly, and dispose of them safely. Avoid self-medication, combining medications without consulting your doctor, stopping medications suddenly, sharing medications, and taking expired medications. If you have any questions or concerns, consult with your healthcare provider.

Drinking alcohol with Aciloc 300 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So, try to avoid consuming alcohol.

Ranitidine and omeprazole are both used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - ACI0006

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