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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Acton Injection 5 ml is indicated for the treatment of infantile spasms in infants and children under two years of age. It can also be indicated for the treatment of exacerbations of multiple sclerosis in adults. Besides this, it is used to treat various chronic inflammatory or autoimmune conditions, including rheumatic, collagen disorders, dermatologic, allergic conditions, ophthalmic, respiratory, and oedema. Acton Injection 5 ml contains Corticotropin, a natural form of adrenocorticotropic hormone (ACTH). It interacts with melanocortin receptors and may affect cell activity relating to your condition. It also works with the body’s immune system to help reduce inflammation associated with certain chronic inflammatory or autoimmune diseases.

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Whats That

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Composition :

CORTICOTROPIN-60IU

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Acton Injection 5 ml

Acton Injection 5 ml belongs to a class of medications called adrenocorticotropic hormone (ACTH) analogue. It is indicated as monotherapy for the treatment of infantile spasms in infants and children under two years of age. It can also be indicated for the treatment of exacerbations of multiple sclerosis in adults. Besides this, it is used to treat various chronic inflammatory or autoimmune conditions, including rheumatic, collagen disorders, dermatologic, allergic conditions, ophthalmic, respiratory, and oedema. Infantile spasms, sometimes called West syndrome, are a type of seizure that occurs in babies.

Acton Injection 5 ml contains Corticotropin, a natural form of adrenocorticotropic hormone (ACTH). It interacts with melanocortin receptors and may affect cell activity relating to your condition. It also works with the body’s immune system to help reduce inflammation associated with certain chronic inflammatory or autoimmune diseases.

Acton Injection 5 ml will be administered by a healthcare professional; do not self-administer. The common side effects of Acton Injection 5 ml include fluid retention (accumulation of fluid in body tissues and cavities), elevation in blood pressure, behavioural and mood changes, increased appetite, weight gain, convulsions, high blood pressure, irritability, fever, increased risk of infection, insomnia (difficulty sleeping) and headache. Most of these side effects do not require medical attention and will resolve gradually. However, talk to your doctor if you experience these side effects persistently.

Before taking Acton Injection 5 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Inform your doctor if you are pregnant or planning to become pregnant. It is not known whether this drug is excreted in human milk. When treating a nursing mother with Acton Injection 5 ml, a decision should be made whether to discontinue nursing or to discontinue the drug, considering the risk and benefit to the mother. You should not breastfeed unless the doctor advises.

Uses of Acton Injection 5 ml

Treatment of Infantile spasms, Multiple sclerosis, Inflammatory or autoimmune conditions

Directions for Use

A healthcare professional will administer it; do not self-administer.

Medicinal Benefits

Acton Injection 5 ml contains Corticotropin, a natural adrenocorticotropic hormone (ACTH). It interacts with melanocortin receptors and may affect cell activity relating to your condition. Aside from that, it works with the body's immune system to help reduce inflammation associated with some chronic inflammatory or autoimmune disorders such as rheumatic disease, collagen disorders, dermatologic, allergic states, ophthalmic, respiratory, and edematous states (oedema).

How Acton Injection 5 ml Works

Acton Injection 5 ml contains Corticotropin, a natural form of adrenocorticotropic hormone (ACTH). It interacts with melanocortin receptors and may affect cell activity relating to your condition. It also works with the body’s immune system to help reduce inflammation associated with certain chronic inflammatory or autoimmune diseases.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Acton Injection 5 ml

As Acton Injection 5 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly

Drug Warnings

Before taking Acton Injection 5 ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially (+) tuberculin test (a tool for screening for tuberculosis), adrenal insufficiency (when the adrenal glands don't make enough of the hormone cortisol), electrolyte imbalance, fluid retention (oedema), GI perforation, Hyperadrenocorticism (A condition that occurs from exposure to high cortisol levels for a long time), Infections (Bacterial/Fungal/Protozoal/Viral), ocular herpes simplex, osteoporosis (bones become weak and brittle), Peptic Ulcer, and Scleroderma (Chronic hardening and tightening of the skin and connective tissues). The administration of live or live attenuated vaccines is contraindicated in patients receiving Acton Injection 5 ml.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Acton Injection 5 ml:
Coadministration of Acton Injection 5 ml with Baricitinibcan increases the risk of developing serious infections.

How to manage the interaction:
Co-administration of Baricitinib with Acton Injection 5 ml can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Acton Injection 5 ml:
When Clozapine is taken with Acton Injection 5 ml, can increase the effect of Clozapine.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Acton Injection 5 ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Acton Injection 5 ml:
Combining Acton Injection 5 ml with Leflunomide can increase the risk of negative side effects.

How to manage the interaction:
Although taking Leflunomide and Acton Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice symptoms like fever, chills, sore throat, or muscle aches, contact your doctor immediately. Other symptoms to look out for include diarrhea, shortness of breath, weight loss, and pain or burning while urinating." Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

HORMONES

Acton Injection 5 ml Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Acton Injection 5 ml. However, as a precautionary measure, it is advisable to avoid or limit alcohol consumption.

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Pregnancy

Caution

It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. So, inform your doctor before receiving Acton Injection 5 ml if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether this drug is excreted in human milk. When treating a nursing mother with Acton Injection 5 ml, a decision should be made whether to discontinue nursing or to discontinue the drug, considering the risk and benefit to the mother. You should not breastfeed unless the doctor advises.

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Driving

Caution

Acton Injection 5 ml may cause physical weakness and Convulsions; it may impact on your ability to drive or operate machinery; therefore, do not drive or operate machinery.

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Liver

Caution

If you have liver problems, inform your doctor before taking Acton Injection 5 ml. Your doctor will weigh the benefits and potential risks before prescribing Acton Injection 5 ml.

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Kidney

Caution

If you have kidney problems, inform your doctor before taking Acton Injection 5 ml. Your doctor will weigh the benefits and potential risks before prescribing Acton Injection 5 ml.

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Children

Safe if prescribed

It can be used in children over two years of age. Your doctor will weigh the benefits and risks before prescribing this medicine for your child.

Have a query?

FAQs

Acton Injection 5 ml is used to treat Infantile spasms, Multiple sclerosis, Inflammatory or autoimmune conditions.

Acton Injection 5 ml contains Corticotropin, a natural form of adrenocorticotropic hormone (ACTH). It interacts with melanocortin receptors and may affect cell activity relating to your condition. Aside from that, it works with the body's immune system to help reduce inflammation associated with some chronic inflammatory or autoimmune disorders.

Acton Injection 5 ml may cause behavioural and mood changes. People taking Acton Injection 5 ml should be closely monitored for their behaviour. Speak with your doctor immediately if you need to.

Common adverse reactions for Acton Injection 5 ml are fluid retention, alteration in glucose tolerance (Glucose levels are higher during the evening compared with morning), elevation in blood pressure, behavioural and mood changes, increased appetite and weight gain.

Country of origin

India

Manufacturer/Marketer address

K-28/1, Additional Midc , Anand Nagar , Ambernath - 421506 , India
Other Info - ACT0109

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