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  3. Admatop 2.5 Injection 1's

Admatop 2.5 Injection 1's, Pack of 1 INJECTION
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Composition :

TOPOTECAN-2.5MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Admatop 2.5 Injection

Admatop 2.5 Injection belongs to a group of medicines called 'anti-cancer/anti-neoplastic agents', used to treat ovarian and small cell lung cancer. On the other hand, it may use to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. It may sometimes be used to treat other cancers. Ovarian cancer begins in the ovaries (a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Admatop 2.5 Injection contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

The amount of medicine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule. Admatop 2.5 Injection is prescribed by a doctor experienced in the use of medications to treat cancer. You may sometimes experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses, and electrolyte disturbances. Most of these side effects of Admatop 2.5 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Admatop 2.5 Injection for as long as your doctor has prescribed. Do not stop using the Admatop 2.5 Injection midway. Talk to your doctor before taking Admatop 2.5 Injection if you have severe allergic reactions to Admatop 2.5 Injection or other medicines or suffer from severe lung problems, Infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Admatop 2.5 Injection if you are pregnant or breastfeeding because this Admatop 2.5 Injection can cause harmful effects on the unborn baby. Both women and men using this Admatop 2.5 Injection should use birth control to avoid pregnancy.

Directions for Use

• Admatop 2.5 Injection is prescribed and administered based on your medical condition and treatment plan as determined by your doctor.• This injection is given only by qualified healthcare professionals experienced in administering cancer therapies.• It must not be self-administered, as it requires careful handling and monitoring during and after administration.• You will be closely monitored during treatment to ensure your safety and treatment effectiveness.

Medicinal Benefits

Admatop 2.5 Injection contains 'Topotecan', which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or together with other chemotherapy drugs depending on the type of cancer you have.

How Admatop 2.5 Injection Works

Admatop 2.5 Injection contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Admatop 2.5 Injection
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Admatop 2.5 Injection

Admatop 2.5 Injection is a parenteral formulation, hence the chance of overdose may be less. However, keep track of your medicine as an overdose of Admatop 2.5 Injection may cause serious side effects such as myelosuppression, increased hepatic enzymes, etc. Seek immediate medical attention if you observe any of these side effects. If an overdose is suspected, observe the patient.

Drug Warnings

Admatop 2.5 Injection will be administered by a healthcare professional. To treat your condition effectually, continue taking Admatop 2.5 Injection for as long as your doctor has prescribed. Do not stop Admatop 2.5 Injection midway. Talk to your doctor before taking Admatop 2.5 Injection if you have severe allergic reactions to Admatop 2.5 Injection or other medicines or suffer from severe lung problems, Infections, renal dysfunction, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), hepatic disorders. Admatop 2.5 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Admatop 2.5 Injection if you are pregnant or breastfeeding because this Admatop 2.5 Injection can cause harmful effects on the unborn baby. Both women and men using this Admatop 2.5 Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Admatop 2.5 Injection treatment and appropriate until recovery is achieved. Do not receive any kind of immunization or vaccination without your doctor's approval while taking the Admatop 2.5 Injection.

Drug-Drug Interactions

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TopotecanBaricitinib
Severe
TopotecanCarboplatin
Severe

Drug-Drug Interactions

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TopotecanBaricitinib
Severe
How does the drug interact with Admatop 2.5 Injection:
Coadministration of baricitinib and Admatop 2.5 Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Admatop 2.5 Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TopotecanCarboplatin
Severe
How does the drug interact with Admatop 2.5 Injection:
When carboplatin is used with Admatop 2.5 Injection, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of carboplatin with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
TopotecanClozapine
Severe
How does the drug interact with Admatop 2.5 Injection:
When Clozapine is taken with Admatop 2.5 Injection, the effect of Clozapine in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Admatop 2.5 Injection and Clozapine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, weight loss, pain or burning during urination - it's important to contact your doctor right away. They may be able to recommend other options that won't cause any problems with your current medications. Do not stop using any medications without a doctor's advice.
TopotecanEtanercept
Severe
How does the drug interact with Admatop 2.5 Injection:
When Etanercept is used with Admatop 2.5 Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Admatop 2.5 Injection and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
TopotecanTofacitinib
Severe
How does the drug interact with Admatop 2.5 Injection:
Taking Tofacitinib with Admatop 2.5 Injection may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Admatop 2.5 Injection, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TopotecanInfliximab
Severe
How does the drug interact with Admatop 2.5 Injection:
Combining Infliximab with Admatop 2.5 Injection can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Admatop 2.5 Injection with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TopotecanThalidomide
Severe
How does the drug interact with Admatop 2.5 Injection:
Taking thalidomide together with Admatop 2.5 Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Admatop 2.5 Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Admatop 2.5 Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Admatop 2.5 Injection.

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Pregnancy

Unsafe

Admatop 2.5 Injection should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Admatop 2.5 Injection and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Admatop 2.5 Injection should not be used during breastfeeding as it passes into the breastmilk and may harm your baby. Hence, if you are breastfeeding, inform your doctor before receiving this medicine.

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Driving

Caution

Admatop 2.5 Injection may affect your reactions and your ability to drive.Note: Possible side effects of chemotherapy with Admatop 2.5 Injection may occur, such as nausea and vomiting. If you are affected by these side effects, do not drive and/or operate machines that require your alertness.

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Liver

Caution

If you have had a history or evidence of liver impairment, please inform your doctor before taking the Admatop 2.5 Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

If you have had a history or evidence of kidney diseases, please inform your doctor before taking the Admatop 2.5 Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Unsafe

The safety and effectiveness of Admatop 2.5 Injection in pediatric patients have not been established. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

Have a query?

FAQs

Admatop 2.5 Injection belongs to a group of medicines called anti-cancer drugs used in the treatment of ovarian cancer and small cell lung cancer. It is also used to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible.

Admatop 2.5 Injection contains 'Topotecan'. Topotecan works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

If you are allergic to topotecan or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Admatop 2.5 Injection.

Yes, Admatop 2.5 Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Avoid taking Admatop 2.5 Injection if you are pregnant because Admatop 2.5 Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Admatop 2.5 Injection.

The live vaccine may not work while on treatment with Admatop 2.5 Injection. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Admatop 2.5 Injection is used to treat ovarian or small cell lung cancer that has come back after chemotherapy. On the other hand, it can also treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. When treating cervical cancer, Admatop 2.5 Injection is used with another medication called cisplatin.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - ADM0077

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 17, 2025 | 10:57 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.4159.pdf
  2. https://www.drugs.com/drug-interactions/topotecan.htmlhttp://chemocare.com/chemotherapy/drug-info/Topotecan.aspx#:~:text=What%20Topotecan%20Is%20Used%20For,(small%20cell%20lung%20cancer).
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