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compositionComposition:ANASTROZOLE-1MG
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Prescription Medicine
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ANASTROZOLE-1MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Adnast Tablet

Adnast Tablet is a prescription oral tablet primarily used to treat hormone receptor-positive breast cancer in women who have completed menopause. It is prescribed both for early-stage breast cancer to prevent recurrence and for advanced-stage cancer to help control its spread. To achieve the best clinical outcomes, this medication must be taken consistently every single day at the same time.

You can take Adnast Tablet with or without food. To support your treatment, doctors often recommend certain lifestyle adjustments, such as eating a balanced diet rich in calcium and vitamin D, and participating in regular, low-impact weight-bearing exercises. These habits help maintain your bone strength and overall physical health during your therapy.

While taking Adnast Tablet, some people may experience mild side effects like hot flashes, joint stiffness, or fatigue. If you experience severe side effects, such as chest pain, severe skin rashes, or sudden shortness of breath, contact your doctor right away.

Before starting this medication, tell your doctor if you have a history of osteoporosis, high cholesterol, liver disease, or kidney issues. Do not take this if you are pregnant, planning to become pregnant, breastfeeding, or have not yet gone through menopause.

This medicine can interact with other treatments, particularly estrogen-containing therapies and tamoxifen, which can make it less effective. If you are taking any other medications, supplements, or herbal products, discuss them with your healthcare provider. Elderly individuals may require closer monitoring by their doctor during treatment.

Uses of Adnast Tablet

Adnast Tablet is used in the treatment of breast cancer in women after menopause. The detailed uses of Adnast Tablet are as follows:

  • Early Breast Cancer: Adnast Tablet helps reduce the risk of cancer returning in postmenopausal women who have hormone receptor-positive early breast cancer, typically after surgery or other primary treatments.
  • Advanced Breast Cancer: Adnast Tablet helps slow down or stop the progression of hormone receptor-positive breast cancer that has spread to other parts of the body in postmenopausal women.

Key Benefits

Adnast Tablet offers significant clinical benefits for postmenopausal women managing hormone-sensitive breast cancer. By targeting the hormones that fuel cancer cells, it helps patients manage their health and maintain their daily routines with confidence.

  • Lower Risk of Cancer Return: For early-stage breast cancer, it significantly decreases the chances of the disease coming back, supporting long-term recovery.
  • Slowing Disease Progression: In advanced cases, it works effectively to keep the cancer from spreading further, helping to extend and improve the quality of life.
  • Convenient Daily Tablet: As an oral medication taken at home, it offers a highly convenient treatment option that fits easily into your daily schedule without requiring frequent clinic visits for intravenous therapy.

Directions for Use

To get the full benefit of Adnast Tablet, follow these step-by-step instructions carefully:

  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
  • Take the medicine at the same time every day to keep a steady amount of the drug in your body.
  • You can take this medication with or without food, according to your preference.

Always follow your doctor's exact instructions regarding how long to take this medicine. Do not stop taking it suddenly or change your schedule without consulting your doctor first.
 

How Adnast Tablet Works

ANASTROZOLE is the active ingredient in this medicine is an aromatase inhibitor. It works by binding to and blocking the aromatase enzyme, which prevents the conversion of other hormones into estrogen. By significantly lowering estrogen levels in the body, Adnast Tablet starves the breast cancer cells of the fuel they need to grow, effectively halting or slowing down their spread. Many breast cancers in postmenopausal women are hormone receptor-positive, meaning they rely on the hormone estrogen to grow and multiply. After menopause, the ovaries stop producing estrogen, but the body continues to make small amounts of it. This process happens when an enzyme called aromatase converts other hormones in fat and muscle tissues into estrogen.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Adnast Tablet to avoid unpleasant side effects. Alcohol intake, along with Adnast Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Adnast Tablet should not be used during pregnancy because it causes harm to the fetus (newborn baby). Please discuss any concerns regarding this with your doctor.

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Breast Feeding

Unsafe

Adnast Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Unsafe

Adnast Tablet may cause dizziness and drowsiness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

Please consult your doctor if you have a history or evidence of any liver-related diseases.

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Kidney

Consult your doctor

Please consult your doctor if you have a history or evidence of any kidney-related diseases.

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Children

Unsafe

Adnast Tablet should not be used by children, as efficacy and safety have not been established.

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Heart

Unsafe

Adnast Tablet is not recommended for use in heart patients as it can lead to cardiovascular effects. However, consult your physician.

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Geriatrics

Safe if prescribed

Adnast Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Adnast Tablet

If you suspect an overdose or have taken more than your prescribed amount, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

Implementing targeted lifestyle adjustments can support your body and manage side effects during your treatment with Adnast Tablet:

  • Protect Your Bones: Since lowering estrogen can lead to bone thinning, include plenty of calcium-rich foods (like dairy, leafy greens, and fortified foods) in your diet. Ask your doctor if calcium and vitamin D supplements are right for you.
  • Stay Physically Active: Perform weight-bearing exercises like brisk walking, yoga, or light strength training at least three times a week to keep your bones strong and reduce joint stiffness.
  • Manage Cholesterol Levels: Eat a heart-healthy diet rich in whole grains, vegetables, and lean proteins, and low in saturated fats, as this medication can sometimes affect your lipid profile.
  • Stay Hydrated: Drink plenty of water throughout the day to help ease joint discomfort and maintain your energy levels.

Have a query?

How Soon It Starts Working

  • The time required for Adnast Tablet to start to work: The time required for Adnast Tablet to show its action is unknown.
  • The time for which the effects of Adnast Tablet last: The effect of Adnast Tablet lasts for 24 hours.

What if you forget to take Adnast Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and return to your regular dosing schedule. Do not take a double dose to make up for a missed tablet.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor Bone Density: Discuss getting a baseline bone density scan (DEXA scan) before starting therapy, and schedule regular follow-ups to monitor your bone health.
  • Use Non-Hormonal Contraception: If there is any chance you could be fertile, use highly effective non-hormonal birth control during treatment and for at least 5 weeks after stopping, as hormonal options can interfere with this medication.
  • Be Cautious Driving: If you experience dizziness, drowsiness, or fatigue while taking this medicine, avoid driving or operating heavy machinery until you know how it affects you.
  • Track Your Lab Work: Attend all scheduled appointments for blood tests, as your doctor will need to monitor your cholesterol and liver function periodically.
  • Report Skin Changes Immediately: Tell your doctor right away if you notice any peeling skin, painful mouth ulcers, or a spreading rash.

verifiedApollotooltip

Using Adnast Tablet alongside other substances can alter how the medication works or increase your risk of side effects. Always share a complete list of your current medicines with your healthcare provider.
Drug-Drug Interactions:

Estrogen-Containing Therapies: Medications such as hormone replacement therapy (HRT) or estrogen-containing birth control can prevent Adnast Tablet from working effectively.

Tamoxifen: Taking tamoxifen at the same time can lower the levels of Adnast Tablet in your blood, reducing its ability to treat the cancer.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions:

Osteoporosis: This medicine reduces estrogen, which can further lower your bone mineral density and increase your risk of bone fractures.

Liver or Kidney Disease: Severe liver damage or kidney issues may affect how your body processes this medicine, requiring extra monitoring from your doctor.

High Cholesterol: This medication can elevate blood lipid levels, which may require monitoring if you have pre-existing cardiovascular risks.

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Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Adnast Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menstrual periods).

Adnast Tablet works by blocking the aromatase enzyme, which is involved in producing the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Adnast Tablet prevents the growth of cancer cells. Together, Adnast Tablet helps prevent or stop the growth of tumours (cancer cells) in other body parts.

Do not stop taking Adnast Tablet on your own. Depending on your medical condition, you are advised to take Adnast Tablet for as long as your doctor has prescribed it for you. Do not hesitate to speak with your doctor if you experience difficulty while taking Adnast Tablet.

Adnast Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any signs of tendon pain or swelling while taking Adnast Tablet.

Adnast Tablet may cause weight gain due to an increase in appetite. However, it is not very common. If you gain weight, eat a low-calorie diet and exercise regularly to maintain proper weight.

Yes, Adnast Tablet commonly affects the hair by making it thin, which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Adnast Tablet. These effects are not long-lasting and may return after some time. If it matters to you, then inform your doctor of another alternative medicine to avoid harm to your hair.

The side effects of Adnast Tablet include headache, nausea, hot flashes, skin rashes, weakness, and musculoskeletal (bone, muscle, or joint) pain. If these side effects persist or worsen, please consult your doctor.

Adnast Tablet is used by bodybuilders who use anabolic steroids for bodybuilding to reduce estrogen production, which is a side effect of anabolic steroids. Increased estrogen levels in bodybuilders may result in shrinking of the testicles or penis, high pitched female voice, and breast enlargement. In order to avoid such characteristics, bodybuilders use Adnast Tablet.

Adnast Tablet can be taken at any time of the day. Take it exactly as advised by your doctor. It can be taken with or without food. Do not break, crush, or chew it.

While on Adnast Tablet, your doctor will recommend blood tests to check blood cell counts and investigate kidney and liver functions. In addition, if you are at risk for osteoporosis, which may also occur due to Adnast Tablet, your doctor may advise a bone scan.

You should contact your doctor if you experience any severe adverse reactions. In case of prolonged or severe vomiting or nausea, extreme pain and extreme weakness, inform your doctor. Additionally, if you have taken more than the recommended dose of Adnast Tablet, consult your doctor.

The most important information that you need to know while using Adnast Tablet is that it can cause heart disease. Women with early-stage breast cancer and blockage of arteries in the heart may have an increase in symptoms of decreased blood flow to their heart. If you experience shortness of breath or have new or worsening chest pain, seek medical help.

Adnast Tablet should not be used with tamoxifen as it may reduce its effectiveness. Medicines containing estrogen such as estrogen creams, birth control pills, vaginal rings, and vaginal suppositories may affect the working of Adnast Tablet.

No, Adnast Tablet is specifically designed and approved for postmenopausal women. It is not effective for women whose ovaries are still producing active levels of estrogen. Talk to your doctor to discuss appropriate options for premenopausal therapy.

The duration of treatment depends on your specific condition and response, but it is typically prescribed for 5 to 10 years for early-stage breast cancer. Do not stop taking this medication early without consulting your oncologist. Talk to your doctor if you have concerns about the length of your treatment.

Joint pain and stiffness are common side effects due to the reduction of estrogen. Staying physically active with low-impact exercises, maintaining a healthy weight, and staying hydrated can help manage these symptoms. Talk to your doctor before taking any over-the-counter pain relievers.

You should avoid estrogen-containing creams, rings, or patches, as they introduce estrogen back into your body and can stop this medication from working properly. Talk to your doctor about safe, non-hormonal ways to manage menopausal symptoms.

Always inform your surgeon, dentist, and entire healthcare team that you are taking this medication. While it does not typically need to be stopped before procedures, your overall bone health and safety must be assessed. Talk to your doctor before scheduling any surgical procedures.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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