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  3. Advin Injection 5 ml

Advin Injection 5 ml, Pack of 1 Injection
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Composition :

VINORELBINE-10MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Advin Injection 5 ml

Advin Injection 5 ml belongs to the group of medicines called vinca alkaloids used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer that has spread to other body parts and advanced breast cancer that has not responded to other medicines.

Advin Injection 5 ml contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body.

In some cases, Advin Injection 5 ml may cause side effects such as nausea, vomiting, constipation, injection site reactions, and a decrease in white and red blood cells. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Advin Injection 5 ml if you are pregnant, breastfeeding, or think you may be pregnant. Advin Injection 5 ml is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Advin Injection 5 ml

Treatment of Non-small cell lung cancer and breast cancer

Directions for Use

Advin Injection 5 ml will be administered by a doctor with experience in the use of chemotherapy medications.

Medicinal Benefits

Advin Injection 5 ml belongs to the group of medicines called vinca alkaloids used to treat locally advanced or metastatic non-small cell lung cancer and advanced breast cancer that has not responded to other medicines. It may also be used to treat cancer of the oesophagus and soft tissue sarcoma (cancer that forms in the muscles). Advin Injection 5 ml contains Vinorelbine, which works by stopping the growth and multiplication of cancer cells. 

How Advin Injection 5 ml Works

Advin Injection 5 ml contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Advin Injection 5 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

What if I have taken an overdose of Advin Injection 5 ml

As Advin Injection 5 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. No specific side effects have been reported under these circumstances.

Drug Warnings

Do not use Advin Injection 5 ml if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have a history of heart attack, severe chest pain, liver problems, and signs or symptoms of infection. Consult the doctor immediately if you become pregnant during treatment with Advin Injection 5 ml. Seek immediate medical attention if you experience symptoms of pulmonary embolism (chest pain, breathlessness, and fainting), posterior reversible encephalopathy syndrome (headaches, changed mental state which may lead to confusion and coma, convulsions, blurred vision and high blood pressure), infection (cough, fever, and chills), severe constipation with abdominal pain, acute respiratory distress syndrome (difficulty breathing), severe reduced blood pressure (severe dizziness and lightheadedness when you stand up), severe chest pain, or allergic reactions (dizziness, rash, swelling of the eyelids, face, lips or throat).

Drug-Drug Interactions

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VinorelbineInfliximab
Severe
VinorelbineCladribine
Severe

Drug-Drug Interactions

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VinorelbineInfliximab
Severe
How does the drug interact with Advin Injection 5 ml:
When Advin Injection 5 ml and Infliximab are taken together, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Advin Injection 5 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VinorelbineCladribine
Severe
How does the drug interact with Advin Injection 5 ml:
Combining Cladribine with Advin Injection 5 ml can increase the risk and severity of developing serious infections.

How to manage the interaction:
Taking Cladribine with Advin Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
VinorelbineEtanercept
Severe
How does the drug interact with Advin Injection 5 ml:
When Etanercept is used with Advin Injection 5 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Advin Injection 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
VinorelbinePosaconazole
Severe
How does the drug interact with Advin Injection 5 ml:
Combining posaconazole and Advin Injection 5 ml can raise the levels of Advin Injection 5 ml in the blood and increase its effects.

How to manage the interaction:
Although using Posaconazole and Advin Injection 5 ml together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, seizures, unusual or excessive bleeding, easy bruising, paleness, fatigue, fainting, fever, chills, sore throat, or other flu-like symptoms. Do not stop taking any medications without consulting a doctor.
VinorelbineClarithromycin
Severe
How does the drug interact with Advin Injection 5 ml:
When Advin Injection 5 ml is taken with Clarithromycin, it can cause a decrease in the metabolism of Advin Injection 5 ml.

How to manage the interaction:
Although taking Clarithromycin and Advin Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like constipation, stomach pain, or difficulty peeing, it's important to let your doctor know. They can recommend other options that won't cause these problems. You should also contact your doctor right away if you notice any numbness, weakness, trouble walking, or hearing loss. Other symptoms like seizures, bleeding, fatigue, or fever should also be reported to your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods like spinach, lettuce, squashes, broccoli, nuts, seeds, beans, whole wheat pasta, whole wheat bread, brown rice and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Advin Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol affects Advin Injection 5 ml. Please consult your doctor.

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Pregnancy

Unsafe

Do not use Advin Injection 5 ml if you are pregnant or think you may be pregnant. Consult the doctor immediately if you become pregnant during treatment with Advin Injection 5 ml.

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Breast Feeding

Unsafe

Do not take Advin Injection 5 ml if you are breastfeeding. Breastfeeding must be discontinued if treatment with Advin Injection 5 ml is necessary.

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Driving

Caution

In a few people, Advin Injection 5 ml may cause dizziness or lightheadedness. Do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Advin Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Advin Injection 5 ml.

bannner image

Children

Unsafe

Advin Injection 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

Advin Injection 5 ml is used to treat Non-small cell lung cancer and breast cancer.

Advin Injection 5 ml works by stopping or slowing the growth of cancer cells in the body.

Use effective contraception and avoid fathering a child during treatment with Advin Injection 5 ml and four months after the end of the treatment. Discuss with the doctor about sperm conservation prior to treatment with Advin Injection 5 ml, as it may alter your fertility.

Advin Injection 5 ml may cause a severe decrease in white blood cells in the bone marrow. This might increase the risk of developing serious infections. Your doctor may advise regular tests to check the number of white blood cells in your body. Consult the doctor immediately if you experience fever, cough, congestion, sore throat or other signs of infection.

Advin Injection 5 ml may cause constipation. Consult your doctor if you experience constipation; the doctor may advise about changing your diet or using medicines to prevent/treat constipation.

Advin Injection 5 ml is a vesicant. It can cause injection site reactions and extravasation hazards. These can be reduced by shortening the infusion time and flushing with IV fluid.

Yes, Advin Injection 5 ml is effective in the treatment of non-small cell lung cancer and breast cancer. However, its effectiveness may vary from person to person.

Generally, Advin Injection 5 ml is administered intravenously by a doctor with experience in using chemotherapy medications. Do not self-administer.

Advin Injection 5 ml may cause hair loss. If you experience hair loss while on treatment with Advin Injection 5 ml consult your doctor.

The common side effects of Advin Injection 5 ml may include nausea, vomiting, constipation, injection site reactions, bleeding gums, constipation, cough, and stomach pain or tenderness. Do not be reluctant to talk with your doctor if any side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

2/236, KAMBRATH THAZAM, PULLALUR, KURUVATTOOR PO, NA KOZHIKODE Kozhikode Kerala 673012
Other Info - ADV0109

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Keep Refrigerated. Do not freeze.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:32 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3912.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
  3. https://www.nps.org.au/assets/medicines/f2eaaa81-8529-4e70-860c-a53300ff0493.pdf
  4. https://medlineplus.gov/druginfo/meds/a695013.html

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