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  3. AFINITOR 10 MG TABLET 10'S

AFINITOR 10 MG TABLET 10'S, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
AFINITOR 10 MG TABLET is used to treat cancer and to prevent organ rejection. It contains Everolimus which works by stopping cancer cells from reproducing and decreasing the activity of the immune system. In some cases, this medicine may cause side effects such as weakness, infection, cough, diarrhoea, fever, and fatigue. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

EVEROLIMUS

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About AFINITOR 10 MG TABLET

AFINITOR 10 MG TABLET belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

AFINITOR 10 MG TABLET contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take AFINITOR 10 MG TABLET as prescribed by your doctor. You are advised to take AFINITOR 10 MG TABLET for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of AFINITOR 10 MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking AFINITOR 10 MG TABLET for as long as your doctor has prescribed. If you are known to be allergic to AFINITOR 10 MG TABLET or any other medicines, please tell your doctor. Do not take AFINITOR 10 MG TABLET if you are pregnant or planning for pregnancy as AFINITOR 10 MG TABLET may harm the unborn baby. AFINITOR 10 MG TABLET should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. AFINITOR 10 MG TABLET causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of AFINITOR 10 MG TABLET

Treatment of Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

• AFINITOR 10 MG TABLET can be taken with or without food.• It is recommended to take AFINITOR 10 MG TABLET once daily at the same time each day or as advised by your doctor.• Swallow AFINITOR 10 MG TABLET as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

AFINITOR 10 MG TABLET is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. AFINITOR 10 MG TABLET travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

How AFINITOR 10 MG TABLET Works

AFINITOR 10 MG TABLET contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Afinitor 10 Mg Tablet
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.

What if I have taken an overdose of AFINITOR 10 MG TABLET

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to AFINITOR 10 MG TABLET or any other medicines, please tell your doctor. AFINITOR 10 MG TABLET should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take AFINITOR 10 MG TABLET if you have recent surgery, infection and hepatitis B. AFINITOR 10 MG TABLET may weaken your immune system, inform your doctor before taking AFINITOR 10 MG TABLET . AFINITOR 10 MG TABLET may also impair your kidney function. Therefore, monitor your kidney function regularly while taking AFINITOR 10 MG TABLET . AFINITOR 10 MG TABLET may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your AFINITOR 10 MG TABLET . AFINITOR 10 MG TABLET may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take AFINITOR 10 MG TABLET if you are pregnant or planning for pregnancy as AFINITOR 10 MG TABLET may harm the unborn baby. AFINITOR 10 MG TABLET should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. AFINITOR 10 MG TABLET causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusKetorolac
Severe
EverolimusCiclosporin
Severe

Drug-Drug Interactions

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EverolimusKetorolac
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Coadministration of Afinitor 10 Mg Tablet with ketorolac may increase the risk of kidney problems.

How to manage the interaction:
Although taking Ketorolac and Afinitor 10 Mg Tablet together can result in an interaction, but it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, pain, weakness, tiredness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
EverolimusCiclosporin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking Afinitor 10 Mg Tablet with cyclosporine may significantly increases the blood levels of Afinitor 10 Mg Tablet.

How to manage the interaction:
Although taking Afinitor 10 Mg Tablet and ciclosporin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusNeomycin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Afinitor 10 Mg Tablet can cause kidney issues, and taking it with Neomycin, can enhance the risk.

How to manage the interaction:
Although taking Afinitor 10 Mg Tablet and Neomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusIopamidol
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Injections of iopamidol and related contrast agents can occasionally cause kidney damage and mixing it with Afinitor 10 Mg Tablet, may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Afinitor 10 Mg Tablet and Iopamidol, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EverolimusBacitracin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Afinitor 10 Mg Tablet can cause kidney issues, and taking it with bacitracin, can enhance the risk.

How to manage the interaction:
Although taking Bacitracin and Afinitor 10 Mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medication without consulting a doctor.
EverolimusFosamprenavir
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking Afinitor 10 Mg Tablet with Fosamprenavir can considerably raise blood levels of Afinitor 10 Mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Taking Afinitor 10 Mg Tablet with Fosamprenavir together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusClarithromycin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking clarithromycin with Afinitor 10 Mg Tablet may increase the blood levels of Afinitor 10 Mg Tablet, which might make you more likely to develop serious side effects (pneumonitis - inflammation of the lungs, mouth ulcers, infection, anemia, or bleeding).

How to manage the interaction:
Although taking clarithromycin and Afinitor 10 Mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue the medication without consulting a doctor.
EverolimusFlurbiprofen
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Using Afinitor 10 Mg Tablet and Flurbiprofen can increase the risk of kidney problems.

How to manage the interaction:
Although taking Afinitor 10 Mg Tablet and Flurbiprofen together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
EverolimusRifabutin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking Afinitor 10 Mg Tablet and Rifabutin may reduce the blood levels of Afinitor 10 Mg Tablet, which may make it less effective.

How to manage the interaction:
Co-administration of Afinitor 10 Mg Tablet with Rifabutin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EverolimusFosaprepitant
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
When Afinitor 10 Mg Tablet and Fosaprepitant are taken together, can increase the levels of Afinitor 10 Mg Tablet in the body. This can increase the risk of serious side effects like serious.

How to manage the interaction:
Taking Afinitor 10 Mg Tablet with Fosaprepitant together can result in an interaction, but it can be taken if a doctor has advised it. If you're having symptoms like mouth sores, unusual bleeding, shortness of breath, tiredness, or coughing it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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EVEROLIMUSGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUSGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Afinitor 10 Mg Tablet with grapefruit juice can raise blood levels and enhance the effects of Afinitor 10 Mg Tablet. Since the co-administration of Afinitor 10 Mg Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Afinitor 10 Mg Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking AFINITOR 10 MG TABLET to avoid unpleasant side-effects.

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Pregnancy

Unsafe

AFINITOR 10 MG TABLET is belonging to pregnancy C category. It is not safe in pregnancy as it may causes harm to the unborn baby. Do not conceive a baby while taking AFINITOR 10 MG TABLET .

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Breast Feeding

Unsafe

AFINITOR 10 MG TABLET should not be taken by breastfeeding mothers as it may harm to the new-born baby.

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Driving

Caution

AFINITOR 10 MG TABLET may cause tiredness (fatigue), do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

AFINITOR 10 MG TABLET should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

AFINITOR 10 MG TABLET is likely unsafe in patients with severe kidney disease as it may cause kidney failure which can be dangerous, use AFINITOR 10 MG TABLET only when prescribed by a doctor.

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Children

Unsafe

AFINITOR 10 MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established.

Have a query?

FAQs

AFINITOR 10 MG TABLET is used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer.

AFINITOR 10 MG TABLET is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.

There is no specific duration of treatment with AFINITOR 10 MG TABLET . AFINITOR 10 MG TABLET is continued till benefit is seen or undesirable toxicity or side effects occur.

You should prevent grapefruit or grapefruit juice while taking AFINITOR 10 MG TABLET . This is because taking them together may rise the levels of AFINITOR 10 MG TABLET in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.

AFINITOR 10 MG TABLET can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.

It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.

AFINITOR 10 MG TABLET contains Everolimus, which belongs to the group of medicines known as kinase inhibitors.

Regular monitoring is essential when using AFINITOR 10 MG TABLET . Your doctor may check your blood tests, blood sugar, blood pressure, and kidney function. They may also adjust your dose based on your response to treatment or any side effects that occur. It's essential to report any changes or concerns to your doctor to ensure safe and effective treatment.

While taking AFINITOR 10 MG TABLET , avoiding certain things is essential to ensure your safety. Avoid consuming grapefruit juice and products and St. John's Wort, as they can interact with the medication. Certain antibiotics, antifungals, and medications can also interact with Everolimus, so consult your doctor before taking any new medications. Additionally, consult your doctor before receiving any vaccinations and avoid high-risk activities that may increase the risk of infections and bleeding. It's also important to avoid getting pregnant or fathering a child while taking Everolimus, as well as breastfeeding. Finally, limit your sun exposure to avoid increasing the risk of skin cancer. Always consult your doctor or pharmacist for a comprehensive list of medications and activities to avoid while taking Everolimus.

Before using any medication, including AFINITOR 10 MG TABLET , you should know its purpose, usage, safety profile, precautions, and limitations.

AFINITOR 10 MG TABLET is administered orally in the form of a tablet. Take Everolimus with or without food, as advised by your doctor. Swallow the tablet whole with water; do not crush, break, or chew it. Note: It's important to follow your doctor's instructions and take AFINITOR 10 MG TABLET exactly as prescribed

By regularly monitoring your progress through brain scans and other evaluations, your doctor can determine if AFINITOR 10 MG TABLET is effectively shrinking your brain tumor.

AFINITOR 10 MG TABLET is indeed considered a cytotoxic medication, but it's a targeted therapy that specifically targets cancer cells and inhibits their growth. It's not a traditional chemotherapy medication, but it can still have side effects and be harmful to healthy cells to some extent. If you have any concerns or questions, please consult your doctor or healthcare team to discuss potential risks and benefits and manage any side effects.

Common side effects of AFINITOR 10 MG TABLET may include weakness, infection, sinus inflammation, cough, diarrhoea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of AFINITOR 10 MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - AFI0010

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.drugs.com/mtm/everolimus.html
  2. https://www.medicines.org.uk/emc/files/pil.11084.pdf

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