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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Amaryl MV Tablet is used to treat type 2 diabetes mellitus. It acts by increasing the amount of insulin released by the pancreas. Thus, prevent the blood glucose levels from rising to very high levels and keeps your diabetes under control. It may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE+VOGLIBOSE

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amaryl MV Tablet

Amaryl MV Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. People with type 2 diabetes either do not produce enough insulin or, if any insulin is produced, it is unable to perform its function in the body (insulin resistance).

Amaryl MV Tablet is a combination of Glimepiride, Metformin and Voglibose which help control blood sugar levels. This medicine works by increasing the amount of insulin released by the pancreas. You must continue following the diet and exercise recommended for you whilst on treatment with Amaryl MV Tablet .

Not everyone who is taking Amaryl MV Tablet will get these side effects. The most common side effect of Amaryl MV Tablet is hypoglycemia (low blood glucose levels), characterised by dizziness, sweating, hunger pangs, dry mouth and skin, etc. Other side effects include changes in taste, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Amaryl MV Tablet should be taken with food to avoid an upset stomach. For optimal results, it is recommended to take it at the same time each day. For better advice, your doctor will determine the appropriate dose, which can change quickly depending on your condition. Do not skip your meals, and also carry a form of sugar with you to prevent low blood sugar levels.

Avoid taking Amaryl MV Tablet if you are allergic to it. Amaryl MV Tablet should not be stopped even if you feel better without consulting your doctor, as sugar levels may change. If you stop taking Amaryl MV Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy) and nerve damage (neuropathy). Amaryl MV Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or are planning to get pregnant or breastfeed.

Uses of Amaryl MV Tablet

Amaryl MV Tablet is used in the treatment of Type 2 diabetes mellitus. The detailed uses of Amaryl MV Tablet are as follows: <br/>

  • Management of Type 2 Diabetes: Amaryl MV Tablet effectively controls blood sugar levels in adults with type 2 diabetes, regulating glucose metabolism and maintaining optimal sugar levels.<br/>
  • Enhanced Insulin Sensitivity: Amaryl MV Tablet improves the body's insulin response, facilitating glucose uptake and reducing insulin resistance.<br/>
  • Prevention of Diabetes-Related Complications: Amaryl MV Tablet helps to prevent long-term complications associated with diabetes, such as kidney damage, nerve damage, and vision problems.<br/>

Directions for Use

• Amaryl MV Tablet should be taken before meals or as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Amaryl MV Tablet as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

  • Amaryl MV Tablet contains Glimepiride, Metformin and Voglibose used to treat type 2 diabetes mellitus.
  • Metformin acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin.
  • Voglibose prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine.
  • Amaryl MV Tablet prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.
  • Amaryl MV Tablet also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), and loss of sensation in your hands and feet (diabetic neuropathy).
  • Amaryl MV Tablet also helps to reduce your chance of having a heart attack or stroke.
  • Being a combination of three drugs, Amaryl MV Tablet  reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

How Amaryl MV Tablet Works

Amaryl MV Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Together, these prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Amaryl MV Tablet

Do not take more than the prescribed dose of Amaryl MV Tablet as it may cause overdose resulting in mild hypoglycemia (low blood sugar). If you suspect you have taken overdose or have symptoms of overdose, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor if you are allergic to Amaryl MV Tablet .
  • This medicine should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. Some diabetic patients, while taking Amaryl MV Tablet , might develop a rare but serious condition called lactic acidosis (too much lactic acid accumulated in the blood) that can damage the working of your liver and kidneys, which are required for the elimination of excess lactic acid from the blood.
  • Before you start taking Amaryl MV Tablet , tell your doctor if you’ve ever had pancreatitis (inflammation of the pancreas), kidney disease, or a low vitamin B12 level.
  • Amaryl MV Tablet , when used with insulin, may extremely lower the blood sugar level, leading to a hypoglycemic condition, which can be fatal.
  • Prolonged intake of Amaryl MV Tablet may lower your thyroid-stimulating hormone (TSH); hence, an annual check-up of TSH is recommended.
  • In rare cases, you may also develop a serious skin reaction known as bullous pemphigoid that requires immediate medical attention.
  • It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIodamide
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Amaryl MV Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Amaryl MV Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Amaryl MV Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Amaryl MV Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iopamidol with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iopromide with Amaryl MV Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Amaryl MV Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iomeprol with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Ioversol with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iopentol with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iohexol with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Iopanoic acid with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Amaryl MV Tablet:
Co-administration of Ioglycamic acid with Amaryl MV Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amaryl MV Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, quarter with proteins and quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with wholegrain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

Taking Amaryl MV Tablet with alcohol can cause hypoglycaemia and can also lead to a rare but life-threatening condition known as lactic acidosis. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Consult your doctor

As the data around the use of Amaryl MV Tablet in pregnant women is limited, the use of Amaryl MV Tablet in pregnancy is unknown. Please consult your doctor for advice before using Amaryl MV Tablet .

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Breast Feeding

Consult your doctor

The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take Amaryl MV Tablet without a doctor's advice.

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Driving

Unsafe

Drive only if you are physically stable and mentally focussed, If you experience drowsiness after taking these medications you should not drive or operate any machinery or vehicles.

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Liver

Caution

Amaryl MV Tablet to be taken with caution, especially if you have a history of liver disease.

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Kidney

Caution

Amaryl MV Tablet to be taken with caution, especially if you have a history of Kidney disease

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Children

Unsafe

Amaryl MV Tablet is not recommended for children below the age of 18 years as the safety and effectiveness of Amaryl MV Tablet has not been established in children due to limited evidence.

Have a query?

FAQs

Amaryl MV Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

Hypoglycaemia refers to low blood sugar levels. The symptoms of hypoglycaemia include nausea, headache, irritability, hunger, sweating, dizziness. Amaryl MV Tablet can cause hypoglycaemia. Hypoglycaemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other anti-diabetic medicine along with Amaryl MV Tablet . Diabetics are advised to keep a quick source of sugar like glucose tablets, honey or fruit juice with them.

Amaryl MV Tablet should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

If you feel thirsty after taking Amaryl MV Tablet , it may be because of dehydration as Amaryl MV Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.

If you have been affected with diabetes, you should have a test of HbA1c once in three months.

Yes, long-term usage of Amaryl MV Tablet can cause vitamin B12 deficiency as it interferes with the absorption of vitamin B12 in the stomach. The symptoms can be managed by taking Vitamin B12 supplements as advised by your doctor.

No. Till date there is no clinical evidence that states that Amaryl MV Tablet affects fertility in either men or women.

Lactic acidosis is rare but life threatening condition when, there is too much of lactic acid build up in the bloodstream. Long term intake of Amaryl MV Tablet may lead to lactic acidosis when cells get deprived of the oxygen levels. Symptoms of lactic acidoisis includes burning sensation of muscle, muscle ache, fast breathing, nausea and stomach pain. Immediately contact doctor if you experience any of these symptoms when on Amaryl MV Tablet .

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugar beverages. It will help to balance blood sugar level in your body. So, it is advisable to keep sugar candies with you and consult a doctor immediately.

Follow a diet rich in fibre, low in fat with sufficient carbohydrates, protein, vitamins and minerals. Maintain the regular meal timings and try to have 2-3 healthy snacks between meals such as salads and soups. Use edible oils moderately and drink at least 8-10 glasses of water every day.

You are recommended to avoid white bread, maida, poori, naan, noodles, biryani, fried rice, carrot juice, soups, deep-fried vegetables, creams and vegetable curries with excess oil. Also, avoid mango, seetaphal, jack fruit, fruit salads with ice cream, and fruit-based desserts. Avoid overeating. Avoid shopping when you are hungry. You could be tempted to purchase oil and fried food.

Amaryl MV Tablet acts by encouraging insulin secretion from the β-cells of the pancreas and increase the amount of insulin released by the pancreas. Also, it helps to restore the body's proper response to the insulin it naturally produces.

The symptoms of diabetes include increased hunger, increased urine frequency, and increased thirst. To know the exact condition, your doctor may recommend blood tests, such as fasting blood glucose, post-meal blood glucose and HbA1C.

Store Amaryl MV Tablet at room temperature. Protect from light and moisture. Keep it out of reach of children.

Amaryl MV Tablet may cause side effects such as hypoglycemia (low blood sugar level), taste change, stomach pain, nausea, diarrhea, and headache. If these side effects persist or worsen, please consult your doctor.

No, it is not safe to take alcohol while taking Amaryl MV Tablet as it may cause hypoglycaemia (low blood sugar) and can also lead to a rare but life-threatening condition known as Lactic Acidosis.

Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - AMA0076

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