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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ambistryn S 0.75 gm Injection is an antibiotic used to treat and prevent bacterial infections like tuberculosis (TB), pneumonia, influenza, plague and other infections. It contains Streptomycin, which kills bacteria and treats infection. It may cause common side effects such as vomiting, nausea, vertigo, skin rash, and fever.
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Whats That

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Composition :

STREPTOMYCIN-0.75GM

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ambistryn S 0.75 gm Injection

Ambistryn S 0.75 gm Injection belongs to the group of medicines called 'anti-tuberculosis', primarily used to treat and prevent bacterial infections like tuberculosis (TB), pneumonia, influenza, plague and other infections. Tuberculosis is an infectious bacterial disease that mainly affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Ambistryn S 0.75 gm Injection does not work against infections caused by the virus.

Ambistryn S 0.75 gm Injection contains Streptomycin, an antibiotic that prevents the production of an enzyme known as mycolic acids by bacteria essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism. Thus, Ambistryn S 0.75 gm Injection is effective against Mycobacterium tuberculosis, which causes TB (tuberculosis) and prevents further infection.

Take Ambistryn S 0.75 gm Injection as prescribed by your doctor. You are advised to use Ambistryn S 0.75 gm Injection for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience a skin rash, vomiting, nausea, vertigo, fever and dizziness. Most of these side effects of Ambistryn S 0.75 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Ambistryn S 0.75 gm Injection or other medicines. Disclose your doctor before taking Ambistryn S 0.75 gm Injection if you are pregnant or breastfeeding. Ambistryn S 0.75 gm Injection may cause nerve problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience these symptoms after taking Ambistryn S 0.75 gm Injection. If you have diabetes, dehydration, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking Ambistryn S 0.75 gm Injection.

Uses of Ambistryn S 0.75 gm Injection

Treatment of Bacterial infections

Directions for Use

Ambistryn S 0.75 gm Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Ambistryn S 0.75 gm Injection contains Streptomycin, primarily used to treat and prevent bacterial infections like tuberculosis (TB), pneumonia, influenza and plague. It is an antibiotic that prevents the production of an enzyme known as mycolic acids by bacteria essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism. Thus, Ambistryn S 0.75 gm Injection acts against a bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), and prevents further infection.

How Ambistryn S 0.75 gm Injection Works

Ambistryn S 0.75 gm Injection contains Streptomycin, an antibiotic that prevents the production of an enzyme known as mycolic acids by bacteria essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ambistryn S 0.75 gm Injection
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Ambistryn S 0.75 gm Injection

Injection sites should be alternated as higher doses or prolonged therapy with Ambistryn S 0.75 gm Injection may cause adverse effects. The doctor should take necessary measures to be immediately aware of any toxic signs or symptoms occuring in the patient due to Ambistryn S 0.75 gm Injection.

Drug Warnings

If you are known to be allergic to Ambistryn S 0.75 gm Injection or any other medicines, please tell your doctor. If pregnant or breastfeeding, please inform your doctor before taking the Ambistryn S 0.75 gm Injection. Ambistryn S 0.75 gm Injection may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience these symptoms after taking Ambistryn S 0.75 gm Injection. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking Ambistryn S 0.75 gm Injection. You must regularly undergo blood, urine and hearing tests while taking Ambistryn S 0.75 gm Injection.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ambistryn S 0.75 gm Injection:
Using cidofovir with Ambistryn S 0.75 gm Injection can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ambistryn S 0.75 gm Injection with Cidofovir is not recommended, please consult your doctor before taking it. If you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Ambistryn S 0.75 gm Injection:
Coadministration of Ambistryn S 0.75 gm Injection and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Ambistryn S 0.75 gm Injection and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
StreptomycinEtacrynic acid
Severe
How does the drug interact with Ambistryn S 0.75 gm Injection:
Co-administration of Ambistryn S 0.75 gm Injection with Etacrynic can increase the risk or severity of hearing loss, ringing in the ears, vertigo, and kidney problems.

How to manage the interaction:
Co-administration of Ambistryn S 0.75 gm Injection with Etacrynic acid can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, increased or decreased urination, swelling, body pains, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
StreptomycinMannitol
Severe
How does the drug interact with Ambistryn S 0.75 gm Injection:
Taking Ambistryn S 0.75 gm Injection with Mannitol can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ambistryn S 0.75 gm Injection with Mannitol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, increased or decreased urination, or swelling, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ambistryn S 0.75 gm Injection:
Coadministration of Deferasirox and Ambistryn S 0.75 gm Injection can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Deferasirox and Ambistryn S 0.75 gm Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience a fast heartbeat, anxiety, constipation, cough, dark urine, diarrhea, dizziness, lightheadedness, fainting, fever, hives or welts, itching skin or rash consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ambistryn S 0.75 gm Injection:
Coadministration of Ambistryn S 0.75 gm Injection and Furosemide may increase the risk or severity of hearing or kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Ambistryn S 0.75 gm Injection and Furosemide, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, hearing difficulty, swelling, body aches, increased or decreased urination, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
StreptomycinTubocurarine
Severe
How does the drug interact with Ambistryn S 0.75 gm Injection:
Co-administration of Ambistryn S 0.75 gm Injection with Tubocurarine may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ambistryn S 0.75 gm Injection and Tubocurarine, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or increased heart rate, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
StreptomycinBumetanide
Severe
How does the drug interact with Ambistryn S 0.75 gm Injection:
Co-administration of Ambistryn S 0.75 gm Injection with Bumetanide can increase the levels and side effects of Ambistryn S 0.75 gm Injection like hearing loss, ringing in the ears, vertigo, and kidney problems.

How to manage the interaction:
Co-administration of Ambistryn S 0.75 gm Injection with Bumetanide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience blurred vision, ringing in the ears, muscle cramps, loss of appetite, swelling via feet and ankles, dry, itchy skin, shortness of breath, trouble sleeping, decreased or increased urination, headaches, dizziness, nausea, vomiting, and diarrhea contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ambistryn S 0.75 gm Injection:
Coadministration of Ambistryn S 0.75 gm Injection and Everolimus can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Ambistryn S 0.75 gm Injection and Everolimus together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
StreptomycinCisatracurium
Severe
How does the drug interact with Ambistryn S 0.75 gm Injection:
Co-administration of Ambistryn S 0.75 gm Injection with Cisatracurium may increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Co-administration of Ambistryn S 0.75 gm Injection with Cisatracurium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Caution

Alcohol should not be taken along with Ambistryn S 0.75 gm Injection, it might lead to excessive sleepiness, coughing and mucus formation.

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Pregnancy

Caution

Ambistryn S 0.75 gm Injection should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ambistryn S 0.75 gm Injection.

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Breast Feeding

Caution

Ambistryn S 0.75 gm Injection is excreted in breast milk. Inform the doctor if you are a breastfeeding mother. Ambistryn S 0.75 gm Injection is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Drive with caution if you have taken Ambistryn S 0.75 gm Injection as it might cause dizziness and make driving difficult.

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Liver

Caution

Inform your doctor before receiving the Ambistryn S 0.75 gm Injection if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Ambistryn S 0.75 gm Injection if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Ambistryn S 0.75 gm Injection should only be given to children if required. The dose should be monitored closely as an overdose to children may lead to unpleasant side effects.

Have a query?

FAQs

Ambistryn S 0.75 gm Injection is used to treat bacterial infections.

Ambistryn S 0.75 gm Injection belongs to the group of medicines called 'anti-tuberculosis', containing Streptomycin, primarily used to treat and prevent tuberculosis (TB). It works by preventing the production of an enzyme known as mycolic acids by bacteria essential for cell wall formation (protective coating). Thus, Ambistryn S 0.75 gm Injection acts against a bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis) and prevents the further spread of infection.

Ambistryn S 0.75 gm Injection should be taken with caution in elderly patients. Generally, the doctor will adjust the dose depending on your medical condition.

In some cases, Ambistryn S 0.75 gm Injection may cause allergic reactions. If you get a rash, itchy skin, swelling of the face and mouth or difficulty breathing, immediately stop taking Ambistryn S 0.75 gm Injection and contact your doctor.

Before starting treatment with Ambistryn S 0.75 gm Injection, audiometry and kidney function tests must be done. Also, the current situation of ear and kidney function should be done before starting Ambistryn S 0.75 gm Injection. Therefore, patients with known kidney disease should be given the Ambistryn S 0.75 gm Injection only if the benefits overweight the harms. Inform your doctor about all other medicines you are using.

Ambistryn S 0.75 gm Injection may cause severe nerve problems, and the risk is even higher if you have kidney problems. Also, in older people and infants, the risk is higher. Please closely monitor your hearing and kidney function while using Ambistryn S 0.75 gm Injection.

The dose of Ambistryn S 0.75 gm Injection is determined by a healthcare professional, taking into account several factors, including the type and severity of the infection, the patient's age, weight, and kidney function, as well as their medical history and current medications.

Ambistryn S 0.75 gm Injection is usually given by injection into a muscle or vein. This medication should only be administered by a healthcare professional, who will determine the appropriate dosage and method of administration based on individual patient needs.

Regular symptomatic monitoring is essential to monitor the effects of Ambistryn S 0.75 gm Injection. Audiology tests (audiometry) should also be conducted to detect potential hearing loss. Blood tests, including serum creatinine, should be done to assess kidney function. Furthermore, electrolyte levels (potassium, calcium, and magnesium) should be monitored to detect any imbalances. These investigations help healthcare professionals to identify and address potential side effects and toxicity associated with treatment.

No Ambistryn S 0.75 gm Injection is not an addictive or habit-forming medication.

Ambistryn S 0.75 gm Injection is typically administered through injection, either intravenously (into a vein) or intramuscularly (into a muscle), and is usually given by a healthcare professional.

Ambistryn S 0.75 gm Injection is a parenteral therapy that should only be administered by a healthcare professional. They will determine the appropriate treatment dosage and duration based on your medical condition. Using a higher dose than recommended can lead to serious side effects such as ototoxicity (permanent hearing loss), nephrotoxicity (kidney damage), and neurotoxicity (nerve damage). Follow their instructions carefully to ensure safe and effective treatment.

If you do not experience any improvement in your condition after using Ambistryn S 0.75 gm Injection, you should consult your healthcare practitioner. They can analyse your condition and may modify your dose or treatment method, which is more effective.

The common side effects of the Ambistryn S 0.75 gm Injection are skin rash, vomiting, nausea, vertigo, fever, and dizziness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Resting after taking Ambistryn S 0.75 gm Injection is better because it may cause dizziness, a common side effect. So, drive only if you are alert and omit driving and operating machinery if you feel dizzy.

Ambistryn S 0.75 gm Injection is generally considered safe when you strictly follow the doctor's instructions. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - AMB0003

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