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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amikef 250mg Vial Injection is used to treat bacterial infections. It contains Amikacin sulphate, which works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of the bacterial cell. Thus, it helps treat bacterial infections. In some cases, you may experience certain common side effects such as irritation at the site of application, skin rash, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Synonym :

AMIKACIN

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Amikef 250mg Vial Injection

Amikef 250mg Vial Injection is used to treat bacterial infections. Bacterial infection can be defined as the proliferation/multiplication of harmful strains of bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Amikef 250mg Vial Injection works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, Amikef 250mg Vial Injection helps treat bacterial infections.

Amikef 250mg Vial Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side effects, such as irritation at the site of application, skin rash, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amikef 250mg Vial Injection. Your doctor may advise you to get urine, blood, and hearing tests before and during the treatment to check for signs of side effects. Depending upon the results of these tests, your doctor may adjust the dose of Amikef 250mg Vial Injection. You are advised to be well hydrated before and during the treatment with Amikef 250mg Vial Injection.

Uses of Amikef 250mg Vial Injection

Treatment of Bacterial infections

Directions for Use

Amikef 250mg Vial Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Amikef 250mg Vial Injection belongs to the group of antibiotic medicines called aminoglycosides. Amikef 250mg Vial Injection is used to treat serious bacterial infections caused by bacteria. Amikef 250mg Vial Injection works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. This leads to the death of bacteria.

How Amikef 250mg Vial Injection Works

Amikef 250mg Vial Injection works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, Amikef 250mg Vial Injection helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Amikef 250mg Vial Injection
  • Eat nutrient-rich foods, including carrots, potatoes, fruits, vegetables, and healthy fats.
  • Stay hydrated by drinking plenty of fluids to flush out waste from the body.
  • Exercise regularly for overall wellness.
  • Avoid harmful substances, including excessive alcohol and smoking.
  • Be cautious with medications like ibuprofen, naproxen, and aspirin - consult your doctor before taking them.
  • Seek medical advice to identify and address underlying health issues.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.

What if I have taken an overdose of Amikef 250mg Vial Injection

The overdose of Amikef 250mg Vial Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Amikef 250mg Vial Injection, please inform your doctor immediately.

Drug Warnings

Do not take Amikef 250mg Vial Injection if you are allergic to any of the components, antibiotics related to aminoglycosides, sulphites, if you are suffering from a disorder called myasthenia gravis (severe weakness of muscles in the body), and dehydration. Talk to your doctor before taking Amikef 250mg Vial Injection if you have any kidney problems, or hearing problems such as tinnitus (buzzing or ringing in the ears). You are advised not to drive or operate heavy machinery after taking Amikef 250mg Vial Injection as it may cause dizziness. If you are pregnant or breastfeeding, talk to your doctor before taking Amikef 250mg Vial Injection. The doctor will prescribe you Amikef 250mg Vial Injection only if the benefits outweigh the potential risks.

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of BCG vaccine with Amikef 250mg Vial Injection can reduce its effectiveness.

How to manage the interaction:
Taking Amikef 250mg Vial Injection with the BCG vaccine can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Co-administration of cidofovir with Amikef 250mg Vial Injection can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidofovir with Amikef 250mg Vial Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of tacrolimus with Amikef 250mg Vial Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and tacrolimus together can result in an interaction but can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, irregular urination, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Co-administration of Amikef 250mg Vial Injection with Atracurium can increase the risk of developing breathing difficulties.

How to manage the interaction:
Taking Atracurium with Amikef 250mg Vial Injection together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, palpitations, chest discomfort, or dizziness. Do not discontinue any medications without consulting a doctor.
AmikacinBacitracin
Severe
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Amikef 250mg Vial Injection with Bacitracin can increase the risk of developing side effects like hearing loss, difficulty breathing, or kidney problems.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and bacitracin together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience ringing in the ears, difficulty breathing, vomiting, increased or decreased urination, swelling, muscle cramps, dizziness, or palpitations. Do not stop using any medications without talking to a doctor.
AmikacinMannitol
Severe
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Mannitol with Amikef 250mg Vial Injection can increase the risk of developing side effects. Elderly patients, those who are dehydrated, and those who already have renal disease may be most vulnerable.

How to manage the interaction:
Although taking Mannitol and Amikef 250mg Vial Injection together can cause an interaction, it can be taken if your doctor has suggested it. Consult a doctor if you experience shortness of breath, muscle weakness, irregular urination, palpitations, or vomiting Do not stop using any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Tenofovir disoproxil with Amikef 250mg Vial Injection can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and Tenofovir disoproxil together can result in an interaction, it can be taken when a doctor has prescribed it. Consult the doctor if you experience vomiting, loss of appetite, irregular urination, sudden weight gain or loss, shortness of breath, weakness, or dizziness. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Amikef 250mg Vial Injection with Furosemide can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and furosemide together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Sirolimus with Amikef 250mg Vial Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and sirolimus together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience vomiting, irregular urination, swelling, difficulty breathing, muscle pain, weakness, or palpitation, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amikef 250mg Vial Injection:
Coadministration of Amikef 250mg Vial Injection with Deferasirox can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Amikef 250mg Vial Injection and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience vomiting, irregular urination, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, seek immediate medical attention. Make sure to hydrate while taking these medications. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food such as whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

You are advised not to consume alcohol while taking Amikef 250mg Vial Injection as it may lead to unwanted side-effects.

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Pregnancy

Caution

Amikef 250mg Vial Injection belongs to pregnancy category-D. If you are pregnant, the doctor will prescribe Amikef 250mg Vial Injection only if the benefits outweigh the potential risks.

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Breast Feeding

Caution

If you are breastfeeding, talk to your doctor before taking Amikef 250mg Vial Injection. The doctor will prescribe Amikef 250mg Vial Injection only if the benefits outweigh the potential risks.

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Driving

Caution

Amikef 250mg Vial Injection may cause dizziness, therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Safe if prescribed

Amikef 250mg Vial Injection is safe to be used in people with liver problems if prescribed by a doctor.

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Kidney

Caution

Amikef 250mg Vial Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

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Children

Safe if prescribed

Amikef 250mg Vial Injection can be given to children if prescribed by the doctor. Dose adjustment may be required as per the age and weight of the child.

Have a query?

FAQs

Amikef 250mg Vial Injection is used to treat bacterial infections.

Amikef 250mg Vial Injection belongs to the group of antibiotic medicines called as aminoglycosides. Amikef 250mg Vial Injection is used to treat serious bacterial infections. Amikef 250mg Vial Injection works by inhibiting the production of bacterial proteins which are necessary for the existence of the bacteria. Thereby, leads to the death of bacteria.

Yes, Amikef 250mg Vial Injection may lead to changes in kidney function. Your doctor will advise you to get blood and urine tests to evaluate the levels of protein or white/red blood cells and creatinine or nitrogen in blood samples. Amikef 250mg Vial Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

Yes, Amikef 250mg Vial Injection may cause dizziness. You are advised not to drive or operate heavy machinery after taking Amikef 250mg Vial Injection as it may cause dizziness and can affect vision. Drive or operate machinery only if you are alert.

Yes, antibiotics may cause diarrhoea. Include foods containing probiotics such as yoghurt, cheese, and buttermilk in your diet as it would help in proper digestion. Also, eat fibre-rich food like whole grain, beans, peas, and bananas. Consult your doctor if you have severe diarrhoea. Do not take any anti-diarrheal medicine without consulting your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AMI0130

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